Ruthenium alloys for biosensors

Patent metadata

Field	Value
Publication number	US-2020309724-A1
Application number	US-202016867705-A
Country	US
Kind code	A1
Filing date	May 6, 2020
Priority date	Nov 21, 2016
Publication date	Oct 1, 2020
Grant date	—

Abstract

The present disclosure relates to metal alloys for biosensors. An electrode is made from ruthenium metal or a ruthenium-based alloy. The resulting electrode has physical and electrical property advantages when compared with existing pure metal electrodes.

First claim

1 . A metal alloy for forming an electrode for measuring an analyte, comprising ruthenium and a first alloying element.

2 . The alloy of claim 1 , wherein the first alloying element is selected from the group consisting of aluminum, chromium, copper, nickel, rhenium, and tungsten.

3 . The alloy of claim 1 , wherein the alloy comprises from about 5 at % to about 95 at %, or from about 5 at % to about 45 at %, or from about 50 at % to about 95 at %, or from about 50 at % to about 65 at %, or from about 55 at % to about 75 at %, or from about 65 at % to about 85 at %, or from about 75 at % to about 95 at %, or from about 85 at % to about 95 at %, or from about 95 at % to less than 100 at % ruthenium.

4 . The alloy of claim 3 , wherein the alloy is a binary alloy and the first alloying element is selected from the group consisting of aluminum, chromium, copper, nickel, rhenium, and tungsten.

5 . The alloy of claim 3 , wherein the alloy is a ternary alloy and consists essentially of ruthenium, the first alloying element, and a second alloying element, wherein the first alloying element and the second alloying element are each selected from the group consisting of aluminum, chromium, copper, nickel, rhenium, and tungsten.

6 . A biosensor comprising an electrode made from ruthenium metal or a ruthenium based metal alloy.

7 . An electrode comprising ruthenium metal or a ruthenium based metal alloy.

8 . The electrode of claim 7 , wherein the alloy is a binary alloy consisting essentially of (a) about 55 at % to about 65 at % ruthenium and (b) about 35 at % to about 45 at % of either chromium or tungsten.

9 . The electrode of claim 7 , wherein the alloy is a binary alloy consisting essentially of (a) about 75 at % to about 85 at % ruthenium and (b) about 15 at % to about 25 at % of either chromium or tungsten.

10 . The electrode of claim 7 , wherein the alloy is a binary alloy consisting essentially of (a) about 60 at % to about 70 at % ruthenium and (b) about 30 at % to about 40 at % of aluminum.

11 . The electrode of claim 7 , wherein the alloy is a binary alloy consisting essentially of (a) about 5 at % to about 25 at % ruthenium and (b) about 75 at % to about 95 at % of nickel.

12 . The electrode of claim 7 , wherein the alloy is a ternary alloy consisting essentially of (a) about 20 at % to about 55 at % ruthenium and (b) about 45 at % to about 80 at % combined of nickel and aluminum.

13 . The electrode of claim 7 , wherein the alloy is a ternary alloy consisting essentially of (a) about 20 at % to about 55 at % ruthenium and (b) about 45 at % to about 80 at % combined of chromium and tungsten.

14 . A method of creating a biosensor for measuring an analyte in a biological fluid, comprising:
forming a first electrode from ruthenium metal or a ruthenium based metal alloy on a surface of a substrate.

15 . The method of claim 14 , wherein the ruthenium based metal alloy comprises from about 5 at % to less than 100 at % ruthenium.

16 . The method of claim 15 , wherein the ruthenium based metal alloy further comprises at least one alloying element selected from the group consisting of aluminum, chromium, copper, nickel, rhenium, and tungsten.

17 . The method of claim 14 , wherein the first electrode is formed by co-sputtering.

18 . The method of claim 14 , further comprising forming a reaction chamber in the substrate, the reaction chamber contacting the first electrode.

19 . The method of claim 14 , further comprising forming a reagent layer on the first electrode to form a working electrode.

20 . The method of claim 14 , wherein the first electrode operates as a reference electrode, and further comprising forming a second electrode on the substrate from the ruthenium-based alloy, and placing a reagent layer on the second electrode to form a working electrode.

Assignees

• Materion Corp

Inventors

• Goodwin Kevin V
• Newton Robert R
• Tribick Ian S
• Fontaine Ethan

Classifications

• C23C14/352

  using more than one target (C23C14/56 takes precedence) · CPC title

• C23C14/205 Primary

  by cathodic sputtering · CPC title

• G01N27/301

  Reference electrodes · CPC title

• C22C5/04

  Alloys based on a platinum group metal · CPC title

• C12Q1/001 Primary

  Enzyme electrodes · CPC title