Centrifugal field-flow fractionation device

Patent metadata

Field	Value
Publication number	US-2020122158-A1
Application number	US-201616471878-A
Country	US
Kind code	A1
Filing date	Dec 22, 2016
Priority date	Dec 22, 2016
Publication date	Apr 23, 2020
Grant date	—

Abstract

Provided is a centrifugal field-flow fractionation device in which a liquid sample is less likely to leak from a channel and attachment and detachment work of a channel member is facilitated. By integrally forming an outer peripheral surface 162 and an inner peripheral surface 163 of a channel member 16, the channel member 16 is configured as one hollow member having a channel 161 formed inside. Thus, pressure resistance performance of the channel member 16 is improved, formation of a gap in the channel 161 can be prevented, and deterioration in sealing performance due to secular change is not generated. Accordingly, a liquid sample is less likely to leak from the channel 161. Further, since the channel member 16 can be handled as one member, attachment and detachment work of the channel member 16 is facilitated.

First claim

1 . A centrifugal field-flow fractionation device comprising:
a rotor that rotates about a rotation axis and has an annular shape; a channel member that is provided along an inner peripheral surface of the rotor and has an arc shape, the channel member having an outer peripheral surface that is formed on a side of the rotor and has an arc shape, an inner peripheral surface that is formed on a side of the rotation axis and has an arc shape, a channel for a liquid sample formed inside, an inlet through which the liquid sample flows to the channel, and an outlet through which the liquid sample flows out from the channel; and a rotation drive unit that rotates the rotor so that particles in the liquid sample in the channel are classified by a centrifugal force, wherein the channel member includes a hollow member having the channel formed inside by integrally forming the outer peripheral surface and the inner peripheral surface, wherein the channel member includes a laminate formed of a plurality of layers joined to each other, the plurality of layers including an outer surface layer on which the outer peripheral surface is formed and an inner surface layer on which the inner peripheral surface is formed, wherein the plurality of layers are joined to each other by diffusion bonding.

2 . The centrifugal field-flow fractionation device according to claim 1 , further comprising a fixing member that is provided along the inner peripheral surface of the channel member, and presses and fixes the channel member to the rotor.

3 . (canceled)

4 . (canceled)

5 . The centrifugal field-flow fractionation device according to claim 1 , wherein the plurality of layers are formed of a same kind of material.

6 . The centrifugal field-flow fractionation device according to claim 1 , wherein the channel has a bending portion or a curved portion that changes a flowing direction of the liquid sample in a plane parallel to the outer peripheral surface and the inner peripheral surface.

7 . The centrifugal field-flow fractionation device according to claim 1 , wherein
the channel member has a plurality of divided channels extending in an arc shape and arranged in a radial direction, and the channel is configured by the divided channels communicating with each other.

8 . The centrifugal field-flow fractionation device according to claim 1 , wherein
the channel member has a plurality of the channels formed in a same plane parallel to the outer peripheral surface and the inner peripheral surface, and the inlet and the outlet are formed in a manner corresponding to each of channels.

Assignees

• Shimadzu Corp

Inventors

• Aoki Kengo
• Kato Haruhisa

Classifications

• B01D21/262

  by using a centrifuge · CPC title

• B04B11/06

  Arrangement of distributors or collectors in centrifuges · CPC title

• B03B5/28 Primary

  by sink-float separation · CPC title

• B04B15/00

  Other accessories for centrifuges · CPC title

• B04B11/02

  Continuous feeding or discharging; Control arrangements therefor · CPC title