Method of forming dihydroferulic acid

Patent metadata

Field	Value
Publication number	US-2018135083-A1
Application number	US-201615563990-A
Country	US
Kind code	A1
Filing date	Mar 24, 2016
Priority date	Apr 9, 2015
Publication date	May 17, 2018
Grant date	—

Abstract

The present invention relates to a method of forming dihydroferulic acid comprising providing ferulic acid and incubating the ferulic acid with a bacterial preparation of Lactobacillus johnsonii CNCM 1-1225 or a bacterial preparation of natural derivatives of Lactobacillus johnsonii CNCM 1-1225. An aspect of the invention is a composition comprising dihydroferulic acid and a bacterial preparation of Lactobacillus johnsonii CNCM 1-1225 or its natural derivatives. A further aspect of the invention is a composition comprising ferulic acid and a bacterial preparation of Lactobacillus johnsonii CNCM 1-1225 or its natural derivatives for use in the treatment or prevention of metabolic disease. Further aspects of the invention are the use of a bacterial preparation of Lactobacillus johnsonii CNCM 1-1225 or its natural derivatives; and a kit for preparing a food product.

First claim

1 . Method of forming dihydroferulic acid, comprising providing ferulic acid and incubating the ferulic acid with a bacterial preparation selected from the group consisting of Lactobacillus johnsonii CNCM I-1225 and natural derivatives of Lactobacillus johnsonii CNCM I-1225.

2 . A method according to claim 1 wherein the bacterial preparation comprises a fermentation broth or extract of a fermentation broth of Lactobacillus johnsonii CNCM I-1225 or natural derivatives of Lactobacillus johnsonii CNCM I-1225.

3 . A method according to claim 2 wherein the Lactobacillus johnsonii CNCM I-1225 or natural derivatives of Lactobacillus johnsonii CNCM I 1225 have been at least partially removed from the fermentation broth.

4 . A method according to claim 1 wherein the ferulic acid is obtained by the hydrolysis of bran.

5 . Composition comprising dihydroferulic acid and a bacterial preparation selected from the group consisting of Lactobacillus johnsonii CNCM I-1225 and a natural derivative of Lactobacillus johnsonii CNCM I-1225.

6 . A method for use in the treatment or prevention of metabolic disease comprising administering a composition comprising ferulic acid and a bacterial preparation selected from the group consisting of Lactobacillus johnsonii CNCM I-1225 and a natural derivative of Lactobacillus johnsonii CNCM I-1225 to an individual in need of same.

7 . A method according to claim 6 wherein the metabolic disease is selected from the group consisting of diabetes, hyperlipidemia, hypertension and cardiovascular disease.

8 . A method according to claim 6 wherein the ferulic acid is from a natural source.

9 . A method according to claim 6 wherein the ferulic acid is comprised within hydrolyzed bran.

10 . A composition according to claim 5 wherein the bacterial preparation is a fermentation broth or extract of a fermentation broth of Lactobacillus johnsonii CNCM I-1225 or natural derivatives of Lactobacillus johnsonii CNCM I-1225.

11 . A composition according to claim 5 wherein the bacterial preparation has been spray dried.

12 . A composition according to claim 5 wherein the composition forms part of a food product.

13 . A composition according to claim 12 wherein the food product is selected from the group consisting of beverages, dairy products, petfood, and food supplements.

14 - 15 . (canceled)

Assignees

• Nestec Sa

Inventors

• Bel-Rhlid Rachid
• Minehira Castelli Kaori
• Duboux Stephane
• Poquet Laure

Classifications

• A23C9/1232

  in powdered, granulated or dried solid form · CPC title

• A23K20/111

  Aromatic compounds · CPC title

• A23K50/40

  for carnivorous animals, e.g. cats or dogs · CPC title

• A23L7/104

  Fermentation of farinaceous cereal or cereal material; Addition of enzymes or microorganisms · CPC title

• A23L7/115

  Cereal fibre products, e.g. bran, husk · CPC title