Device for manufacturing cell-derived vesicles and manufacturing method using same
US-2024200008-A1 · Jun 20, 2024 · US
US2017321176A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2017321176-A1 |
| Application number | US-201515525280-A |
| Country | US |
| Kind code | A1 |
| Filing date | Nov 9, 2015 |
| Priority date | Nov 11, 2014 |
| Publication date | Nov 9, 2017 |
| Grant date | — |
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The present invention relates to a cell sheet manufacturing device and a manufacturing method therefor. More specifically, the present invention relates to a cell sheet manufacturing device comprising a support layer made of silicon rubber, a patterned electrode formed adjacent to the support layer and a graphene layer formed adjacent to the electrode, and a manufacturing method therefor.
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1 - 17 . (canceled) 18 . A cell sheet manufacturing device comprising: a support layer; a first sensor disposed on the support layer; and a graphene nanoribbon pattern disposed adjacent to the first sensor on the support layer, wherein cells are attached to the graphene nanoribbon pattern to be cultured. 19 . The cell sheet manufacturing device of claim 18 , further comprising a second sensor disposed adjacent to the first sensor on the support layer. 20 . The cell sheet manufacturing device of claim 19 , wherein the first sensor is an impedance sensor and the second sensor is a temperature sensor. 21 . The cell sheet manufacturing device of claim 20 , wherein the first and second sensors check a state of cell growth and proliferation on the graphene nanoribbon pattern in real time. 22 . The cell sheet manufacturing device of claim 19 , wherein the first and second sensors comprise a serpentine metal pattern. 23 . The cell sheet manufacturing device of claim 22 , wherein the metal pattern and the graphene nanoribbon pattern stretch in the same direction. 24 . The cell sheet manufacturing device of claim 22 , wherein at least a part of the graphene nanoribbon pattern is disposed on the metal pattern. 25 . The cell sheet manufacturing device of claim 18 , wherein the graphene nanoribbon pattern comprise a plurality of micro patterns stretching in a fixed direction and spaced apart from each other. 26 . The cell sheet manufacturing device of claim 18 , wherein the support layer is formed of silicon rubber.
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