Surface Sampling Method, Device, and System for Enhanced Detection of Chemical and Biological Agents

Patent metadata

Field	Value
Publication number	US-2016349172-A1
Application number	US-201514723628-A
Country	US
Kind code	A1
Filing date	May 28, 2015
Priority date	May 28, 2015
Publication date	Dec 1, 2016
Grant date	—

Abstract

A system, method, and device for analyzing a sample using spectroscopy. The system includes a spectroscope, a sample vial with a swab removably sealable within a transparent enclosure, the swab including an absorbent collection substrate. The system further includes a sample vial adaptor configured to affix to the spectroscope, and a sample vial receptacle that receives the sample vial. The adaptor is configured to position the sample vial such that the transparent portion of the enclosure is between the swab and the laser of the Raman instrument, and such that the swab is positioned at the focal distance of the laser.

First claim

What is claimed is:

1 . A system for analyzing a sample using spectroscopy, the system comprising:
a spectroscope; a sample vial comprising a swab removably sealable within an enclosure, the enclosure comprising at least one transparent portion to allow transmission of electromagnetic radiation; and a sample vial adaptor configured to affix to the spectroscope, and further comprising a sample vial receptacle configured to receive the sample vial, wherein the adaptor is configured to position the sample vial such that the transparent portion of the enclosure is between the swab and a laser of the spectroscope, and such that the swab is positioned at the focal distance of the laser.

2 . The system of claim 1 , wherein the sample vial adaptor is configured to reversibly affix to the spectroscope.

3 . The system of claim 1 , wherein the spectroscope comprises a sample chamber, and wherein the sample vial adaptor is configured to insert into the sample chamber of the spectroscope.

4 . The system of claim 1 , wherein the sample vial further comprises a removable cap with a stem extending outwardly, the stem comprising the swab at the end distal to the cap, and further wherein the stem is suspended in the sample vial when the cap is affixed to the sample vial.

5 . The system of claim 4 , wherein the stem comprises an angle at the distal end to position the swab at an approximately 20 degree angle compared to the end of the stem proximal the cap.

6 . The system of claim 1 , wherein the swab comprises an absorbent collection substrate.

7 . The system of claim 1 , wherein the sample vial comprises a positioning tab, and wherein the sample vial receptacle comprises a positioning slot complementary to the positioning tab of the sample vial.

8 . The system of claim 1 , wherein the sample vial adaptor further comprises a probe receptacle configured to receive a probe of Raman instrument.

9 . A method for analyzing a sample using spectroscopy, the method comprising the steps of:
providing a transparent sample vial, the sample vial comprising a collection substrate; swabbing the collection substrate on a surface to be sampled; inserting the collection substrate within the sample vial such that the collection substrate is suspended within the sample vial; placing the sample vial in a sample vial receptacle of a sample vial adaptor, wherein the adaptor is affixed to the spectroscope and is configured to position the sample vial such that the swab is positioned at the focal distance of a laser of the spectroscope; and analyzing the collection substrate using the spectroscope.

10 . The method of claim 9 , wherein the adaptor comprises a mounting post configured to insert into a sample chamber of a spectroscope.

11 . The method of claim 9 , wherein the sample vial comprises a swab removably sealable within an enclosure, the enclosure comprising at least one transparent portion to allow transmission of radiation.

12 . The method of claim 11 , wherein the sample vial further comprises a removable cap with a stem extending outwardly, the stem comprising the swab at the end distal to the cap, and further wherein the stem is vertically suspended in the sample vial when the cap is affixed to the sample vial.

13 . The method of claim 12 , wherein the stem comprises an angle at the distal end to position the collection substrate at an approximately 20 degree angle compared to the end of the stem proximal the cap.

14 . The method of claim 9 , wherein the sample vial comprises a positioning tab, and wherein the sample vial receptacle comprises a positioning slot complementary to the positioning tab of the sample vial.

15 . The method of claim 9 , wherein the sample vial adaptor comprises a probe receptacle configured to receive a probe of spectroscope.

16 . A device for swabbing a surface, the device comprising:
an enclosure, wherein at least a portion of the enclosure is transparent; a cap configured to removably affix to the transparent enclosure; and a stem extending outwardly from the cap, the stem comprising a collection substrate at the end distal to the cap, and further comprising an angle at the distal end to position the collection substrate at an angle compared to the end of the stem proximal the cap; wherein the stem is suspended in the sample vial when the cap is affixed to the transparent enclosure.

17 . The device of claim 16 , wherein the collection substrate comprises quartz fiber.

18 . The device of claim 16 , wherein the angle is approximately 20 degrees.

19 . A sample vial adaptor, the adaptor comprising a sample vial receptacle configured to receive a sample vial comprising a swab removably sealable within an at least partially transparent enclosure, wherein the sample vial adaptor is configured to affix to a spectroscope, and further wherein the sample vial adaptor is configured to position the sample vial such that the transparent portion of the enclosure is positioned between the swab and a laser of the spectroscope, and such that the swab is positioned at the focal distance of the laser.

20 . A system for analyzing a sample using spectroscopy, the system comprising:
a spectroscope; a sample collector comprising a swab at a distal end of a stem; and a sample collector adaptor configured to affix to the spectroscope, and further comprising a sample collector receptacle configured to receive the sample collector, wherein the adaptor is configured to position the swab of the sample collector at the focal distance of the laser.

21 . The system of claim 20 , wherein the stem comprises an angle at the distal end to position the swab at an approximately 20 degree angle compared to a proximal end of the stem.

22 . The system of claim 20 , wherein the swab comprises an absorbent collection substrate.

23 . The system of claim 22 , wherein the absorbent collection substrate comprises quartz fiber.

24 . The system of claim 20 , wherein the sample collector comprises a positioning tab, and wherein the sample collector receptacle comprises a positioning slot complementary to the positioning tab of the sample collector.

25 . The system of claim 20 , wherein the sample collector adaptor further comprises a probe receptacle configured to receive a probe of Raman instrument.

26 . A sample collector adaptor, the adaptor comprising a sample collector receptacle configured to receive a sample collector comprising a swab, wherein the sample collector adaptor is configured to affix to a spectroscope, and further wherein the sample collector adaptor is configured to position the sample collector such that the swab is positioned at the focal distance of the laser.

27 . The sample collector adaptor of claim 26 , wherein the stem comprises an angle at the distal end to position the swab at an approximately 20 degree angle compared to a proximal end of the stem.

28 . The sample collector adaptor of claim 26 , wherein the swab comprises an absorbent collection substrate.

29 . The sample collector adaptor of claim 28 , wherein the absorbent collection substrate comprises quartz fiber.

30 . The sample collector adaptor of claim 26 , wherein the sample collector receptacle comprises a positioning slot complementary to a positioning tab of the sample collector.

31 . Th

Assignees

• Src Inc

Inventors

• Houghton Stephen R
• Roberts Marc P
• Surace Clayton Nicole J
• Mclean James W
• Cannon Robert M

Classifications

• G01N1/10

  in the liquid or fluent state {(burettes, pipettes B01L3/02; sampling of ground water E02D1/06; metering by volume of fluids or fluent solid material G01F11/00, G01F13/00)} · CPC title

• G01N21/65

  Raman scattering · CPC title

• G01N33/227 Primary

  Explosives, e.g. combustive properties thereof · CPC title

• G01N2001/028

  Sampling from a surface, swabbing, vaporising · CPC title

• G01N21/0303 Primary

  Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment (G01N21/031 - G01N21/15 take precedence) · CPC title