Materials and methods for the selective recovery of monovalent products from aqueous solutions using continuous ion exchange

Patent metadata

Field	Value
Publication number	US-2016297747-A1
Application number	US-201615094791-A
Country	US
Kind code	A1
Filing date	Apr 8, 2016
Priority date	Apr 8, 2015
Publication date	Oct 13, 2016
Grant date	—

Abstract

This document describes a process for the high purity and high concentration recovery of monovalent products via continuous ion exchange from aqueous solution for further down-stream purification.

First claim

What is claimed is:

1 . A method of recovering at least one monovalent product from an aqueous solution using continuous ion exchange comprising:
a. adsorbing at least one monovalent product on an ion exchange resin at a pH of approximately the logarithm of a first acid dissociation constant of the at least one monovalent product; b. eluting the at least one monovalent product from the ion exchange resin; and c. charging adsorbent sites on the ion exchange resin with a sufficient amount of protons or proton donors to provide buffering capacity towards the pH of approximately the logarithm of the at least one monovalent product's first acid dissociation constant.

2 . The method of claim 1 , wherein the at least one monovalent product is chosen from fatty acids, monoamines, and amino acids.

3 . The method of claim 2 , wherein the monoamines comprise at least one of 4-aminobutyrate, 5-aminopentanoate, 6-aminohexanoate, and 7-aminoheptanoate.

4 . The method of claim 1 , wherein the at least one monovalent product is eluted from the ion exchange resin with a solution comprising at least one compound chosen from ammonia, ammonium carbonate, and ammonium bicarbonate.

5 . The method of claim 1 , comprising charging the adsorbent site on the ion exchange resin with an acidic solution.

6 . The method of claim 5 , wherein the acidic solution comprises sulphuric acid.

7 . The method of claim 1 , comprising charging the adsorbent sites on the ion exchange resin with an ammonium bicarbonate solution.

8 . The method of claim 1 , further comprising at least one wash step after at least one of steps (a), (b), and (c).

9 . The method of claim 8 , wherein the at least one wash step comprises washing the ion exchange resin with an aqueous solution.

10 . An apparatus for recovering at least one monovalent product from aqueous solutions comprising:
a. an absorption zone to adsorb at least one monovalent product on an ion exchange resin at a pH of approximately the logarithm of a first acid dissociation constant of the at least one monovalent product; b. an elution zone to elute the at least one monovalent product from the ion exchange resin; and c. a proton buffer zone for charging adsorbent sites on the ion exchange resin with a sufficient amount of protons or proton donors to provide buffering capacity towards the pH of approximately the logarithm of the at least one monovalent product's first acid dissociation constant.

11 . The apparatus of claim 10 , wherein the at least one monovalent product is chosen from fatty acids, monoamines, and amino acids.

12 . The apparatus of claim 11 , wherein the monoamines comprise at least one of 4-aminobutyrate, 5-aminopentanoate, 6-aminohexanoate and 7-aminoheptanoate.

13 . The apparatus of claim 10 , wherein the elution zone comprises at least one eluent chosen from ammonia, ammonium carbonate, and ammonium bicarbonate.

14 . The apparatus of claim 10 , wherein the proton buffer zone comprises an ammonium bicarbonate solution for charging the adsorbent sites on the ion exchange resin.

15 . The apparatus of claim 10 , wherein the proton buffer zone comprises an acidic solution for charging the adsorbent site on the ion exchange resin

16 . The apparatus of claim 15 , wherein the acidic solution comprises sulphuric acid.

17 . The apparatus of claim 10 , further comprising at least one wash step zone after at least one of zones (a), (b), and (c).

18 . The apparatus of claim 17 , wherein the at least one wash step zone comprises an aqueous solution for washing the ion exchange resin.

Assignees

• Invista North America Sarl

Inventors

• Conradie Alex

Classifications

• C07C227/40 Primary

  Separation; Purification · CPC title

• B01D15/362 Primary

  Cation-exchange · CPC title

• B01D15/361

  Ion-exchange · CPC title

• B01D15/1892

  the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds or centrifugal chromatography · CPC title

• C07C67/58

  by liquid-liquid treatment · CPC title