Method for surface-modifying neural electrode

Patent metadata

Field	Value
Publication number	US-2016258070-A1
Application number	US-201615056948-A
Country	US
Kind code	A1
Filing date	Feb 29, 2016
Priority date	Mar 4, 2015
Publication date	Sep 8, 2016
Grant date	—

Abstract

In a method for surface-modifying a neural electrode, a neural electrode array is formed, first and second metal nanoparticles having different solubilities with respect to an etching solution are simultaneously electrode-deposited on a surface of the neural electrode array, and the second metal nanoparticles are selectively etched using the etching solution, thereby forming a porous structure including the first metal nanoparticles on the surface of the neural electrode array.

First claim

What is claimed is:

1 . A method for surface-modifying a neural electrode, the method comprising:
forming a neural electrode array; simultaneously electrode-depositing, on a surface of the neural electrode array, first and second metal nanoparticles having different solubilities with respect to an etching solution; and selectively etching the second metal nanoparticles using the etching solution, thereby forming a porous structure including the first metal nanoparticles on the surface of the neural electrode array.

2 . The method of claim 1 , wherein the first metal nanoparticle includes a gold nanoparticle, and the second metal nanoparticle includes a silver nanoparticle.

3 . The method of claim 2 , further comprising combining molecules including a thiol-functional group with the porous structure including the gold nanoparticles.

4 . The method of claim 1 , wherein the first metal nanoparticle includes a platinum nanoparticle, and the second metal nanoparticle includes a gold nanoparticle.

5 . The method of claim 1 , wherein the electrode-depositing is performed by providing, in an electrolyte solution, the neural electrode array as a working electrode, a counter electrode, and a reference electrode.

6 . The method of claim 5 , wherein a platinum plate is used as the counter electrode, and an Ag/AgCl electrode in a KCl saturated solution is used as the reference electrode.

7 . The method of claim 5 , wherein, in the electrode-depositing, an alloy of the first and second metal nanoparticles is formed by applying a voltage ranging from −1.5 V to 1 V to the counter electrode and the working electrode for 0 to 1200 seconds.

8 . The method of claim 5 , wherein the electrolyte solution is selected as a solution in which the different first and second nanoparticles are simultaneously formed using the electrode-depositing.

9 . The method of claim 8 , wherein the electrolyte solution includes 50 mM KAu(CN) 2 , 50 mM K 2 Ag(CN) 3 , 0.2 M KCN, and 0.5 M KOH.

10 . The method of claim 1 , wherein the selectively etching of the second metal nanoparticles includes etching the second metal nanoparticles using the etching solution with 25° C. to 90° C. for 0 to 60 minutes.

11 . The method of claim 10 , wherein the etching solution includes a nitric acid (HNO 3 ) solution.

12 . The method of claim 10 , wherein the etching solution includes a KI solution.

Assignees

• Electronics & Telecommunications Res Inst

Inventors

• Kim Yong Hee
• Jung Sang-Don

Classifications

• A61B5/24 Primary

  Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof · CPC title

• C25D3/48

  of gold · CPC title

• A61B2562/125

  characterised by the manufacture of electrodes · CPC title

• C25D5/10

  Electroplating with more than one layer of the same or of different metals (for bearings C25D7/10) · CPC title

• C25D7/00

  Electroplating characterised by the article coated · CPC title