Improved process for the humanization of animal skim milk

Patent metadata

Field	Value
Publication number	US-2016205960-A1
Application number	US-201415022815-A
Country	US
Kind code	A1
Filing date	Sep 19, 2014
Priority date	Sep 19, 2013
Publication date	Jul 21, 2016
Grant date	—

Abstract

Claimed is the preparation of an infant formula base product, comprising: (a) microfiltration (ME) of animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer and operating with a volume concentration factor of 1.5-8, resulting in a retentate (MFR) and a permeate (MFP); (b) ultrafiltration (UF) of the MEP originating from step (a) over a membrane having a molecular weight cut-off of at most 25 kDa and operating with a volume concentration factor of 1.5-8, resulting in a retentate (UFR) and a permeate fUEP); (c) combining the MFR from step (a) and the UFR from step (b), to obtain a defined casein/whey ratio. Alternatively, the product of step (a) is used as a protein source. Claimed is also a composition comprising 40-50 g casein, 30-40 g lactose and 5-16 g ash per 100 g dry weight.

First claim

1 .- 23 . (canceled)

24 . A process for the preparation of an infant formula base product, comprising:
(a) microfiltering (MF) animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer and at a volume concentration factor of 1.5-8, resulting in a retentate (MFR) and a permeate (MFP); (b) ultrafiltering (UF) the MFP over a membrane having a molecular weight cut-off of at most 25 kDa at a volume concentration factor of 1.5-8, resulting in a retentate (UFR) and a permeate (UFP); (c) combining part of the MFR and the UFR to obtain a composition having a casein/whey protein weight ratio of 20/80-70/30 for use in a first nutritional product,
wherein a remainder of the MFR is used in the manufacture of a second nutritional product suitable for feeding infants from 6-36 months of age, wherein the second nutritional product comprises less than 50 wt % of protein from a different source.

25 . The process according to claim 24 , wherein step (a) is enhanced with diafiltration, optionally using 50-500 wt % diafiltration water, based on the total volume of the animal skim milk used in step (a).

26 . The process according to claim 24 , wherein step (a) is performed over a ceramic membrane having a porosity of 0.10-0.30 micrometer or over a spiral wound organic membrane having a porosity of 0.10-0.35 micrometer.

27 . The process according to claim 26 , wherein step (a) is performed over a spiral wound organic membrane having a porosity of 0.15-0.25 micrometer.

28 . The process according to claim 24 , wherein step (a) is performed at a temperature from 5-25° C.

29 . The process according to claim 24 , further comprising:
(d) demineralizing at least part of the UFP, resulting in a demineralized UFP,
wherein the demineralized UFP originating from step (d) is subjected to combining step (c).

30 . The process according to claim 29 , wherein the demineralizing comprises:
(d1)nanofiltration (NF) of at least part of the UFP originating from step (b), resulting in a retentate (NF3R) and a permeate (NF3P); (d2) subjecting the NF3R originating from step (d1) to calcium phosphate salt precipitation; (d3)removing the precipitated salts, preferably by filtration, resulting in the demineralized UFP.

31 . The process according to claim 24 , further comprising:
(e) concentrating the UFR, optionally by nanofiltration (NF) over a membrane having a molecular weight cut-off of at most 500 Da, resulting in a retentate (NF2R) and a permeate (NF2P),
wherein the NF2R originating from step (e) is used as UFR in step (c).

32 . The process according to claim 24 , further comprising:
(f) concentrating the MFR, optionally by
(f1) reverse osmosis (RO), resulting in a retentate (ROR) and a permeate (ROP); or
(f2) ultrafiltration (UF) over a membrane having a molecular weight cut-off of at most 25 kDa and operating with a volume concentration factor of 1.5-5, resulting in a retentate (UF2R) and a permeate (UF2P),

wherein the UF2R or the ROR is used as MFR in step (c).

33 . The process according to claim 24 , further comprising:
(g) concentrating the MFP, optionally by reverse osmosis (RO), resulting in a retentate (RO2R) and a permeate (RO2P),
wherein the RO2R is used as MFR in step (b).

34 . The process according to claim 24 , further comprising spray-drying the a combined product of step (c).

35 . The process according to claim 24 , further comprising processing the combined product of step (c) into an infant formula, follow-on formula or growing-up milk.

36 . The process according to claim 34 , further comprising:
(h) combining a part of the MFR with UFP originating from step (b).

37 . The process according to claim 36 , wherein step (h) further comprises combining with an NFP or an ROR as obtained in any of optional steps (d1), (e), (f1) and (g).

38 . A process for the manufacture of a nutritional product suitable for feeding infants from 6-36 months of age, comprising:
(i) microfiltering (MF) animal skim milk over a membrane having a porosity of 0.10-0.35 micrometer at a volume concentration factor of 1.5-8, resulting in a retentate (MFR) and a permeate (MFP); (ii) optionally subjecting the MFR to reverse osmosis (RO), resulting in a retentate (RO2R) and a permeate (RO2P); (iii) combining at least part of an MFR or an RO2R as protein source with one or more additional ingredients selected from whey protein, further lactose, sucrose, fat, vitamins, minerals, an UFP originating from step (iv), prebiotics and probiotics,
wherein the nutritional product comprises at most 50 wt % of protein from a different source than the protein comprised in the MFR originating from step (i).

39 . The process according to claim 38 , further comprising:
(iv) ultrafiltering (UF) an MFP over a membrane having a molecular weight cut-off of at most 25 kDa at a volume concentration factor of 1.5-8, resulting in a retentate (UFR) and a permeate (UFP),
wherein at least part of an UFP originating from step (ii) is used as additional ingredient in combining step (iii).

40 . The process according to claim 38 , wherein the nutritional product comprises less than 10 wt % of protein from a different source than the protein comprised in the MFR originating from step (i).

41 . A casein rich composition comprising
i) 40-50 g casein per 100 g dry weight, ii) 30-40 g lactose per 100 g dry weight iii) 5-16 g ash per 100 g dry weight.

42 . The casein rich composition according to claim 41 , further comprising
iv) 0-10 g whey per 100 g dry weight, v) 0.1-2 g fat per 100 g dry weight, vi) 0.1-5 g non-protein-nitrogen per 100 g dry weight.

43 . The casein rich composition according to claim 41 , comprising:
(a) 1-9 mg sodium per g dry weight, (b) 15-30 mg potassium per g dry weight, (c) 4-14 mg chlorine per g dry weight, (d) 14-24 mg calcium per g dry weight, (e) 0.5-2.5 mg magnesium per g dry weight, (f) 9-19 mg phosphorus per g dry weight.

Assignees

• Nutricia Nv

Inventors

• Tobin John
• Verdurmen Rudolph Eduardus Maria

Classifications

• A23J1/202

  Casein or caseinates · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A23C9/1427

  by dialysis, reverse osmosis or hyperfiltration, e.g. for concentrating or desalting · CPC title

• A23J3/08

  Dairy proteins · CPC title

• A23C9/1425 Primary

  by ultrafiltration, microfiltration or diafiltration of whey, e.g. treatment of the UF permeate · CPC title