Porous biocompatible polymer material and methods

Patent metadata

Field	Value
Publication number	US-2016184483-A1
Application number	US-201615066195-A
Country	US
Kind code	A1
Filing date	Mar 10, 2016
Priority date	Feb 1, 2008
Publication date	Jun 30, 2016
Grant date	—

Abstract

Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described a spacer for spinal fusion, craniornaxillofacial (CMF) structures, and other structures for tissue implants.

First claim

1 . A porous structure for promoting tissue ingrowth, comprising:
a network of polymer granules that are melted together at contact points; a plurality of interstitial spaces between the polymer granules; and a coating of particles substantially lining a surface of the polymer granules.

2 . The porous structure of claim 1 , wherein the structure is a spacer for spinal fusion.

3 . The porous structure of claim 1 , wherein the structure is a craniomaxillofacial (CMF) structure.

4 . The porous structure of claim 1 , wherein the structure is a scaffold structure.

5 . The porous structure of claim 1 , wherein the polymer granules comprise PAEK family polymers.

6 . The porous structure of claim 1 , wherein the polymer granules comprise PEEK.

7 . The porous structure of claim 1 , wherein the polymer granules comprise PCL, PLA, PGA, or a mixture thereof.

8 . The porous structure of claim 1 , wherein the polymer granules comprise polyphenylene, self-reinforced polyphenylene, polyphenylsulphone, polysulphone, PET, polyethylene, polyurethane, or a mixture thereof.

9 . The porous structure of claim 1 , wherein the coating particles comprise calcium powders, bone powder, hydroyapatite, titanium alloys and oxides, barium salts, zirconium oxide, or mixtures thereof.

10 . The porous structure of claim 1 , wherein the coating particles comprise beta-tricalcium phosphate.

11 . The porous structure of claim 1 , further including a biological substance.

12 . The porous structure of claim 11 , wherein the biological substance is autologous.

13 . The porous structure of claim 11 , wherein the biological substance is allogenic.

14 . The porous structure of claim 1 , further including a synthetic small molecule.

15 . The porous structure of claim 1 , further including a hydrolytically degradable coating.

16 . The porous structure of claim 1 , further including a reinforcing structure.

17 . The porous structure of claim 16 , wherein the reinforcing structure is incorporated through the porous structure.

18 . The porous structure of claim 1 , further including one or more radiopaque materials.

19 . The porous structure of claim 1 , wherein the porous structure includes one or more areas of selective compression.

Assignees

• Depuy Synthes Products Inc

Inventors

• Kerr Sean Hamilton
• Recber Ali
• Pepe Thomas
• Messerli Dominique
• Laurence Lawton
• Walsh Ryan
• Kueenzi Thomas
• Randall Brandon

Classifications

• A61P19/08

  for bone diseases, e.g. rachitism, Paget's disease · CPC title

• C08J9/24 Primary

  by surface fusion and bonding of particles to form voids, e.g. sintering (of expandable particles C08J9/232) · CPC title

• A61F2002/30604

  modular · CPC title

• A61L27/18

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• A61F2002/30387

  Dovetail connection · CPC title