Calcium propane-2-sulfinate dihydrate
US-9757367-B2 · Sep 12, 2017 · US
Complexes of agomelatine and sulphonic acids, a process for their preparation and pharmaceutical compositions containing them
US2016159735A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016159735-A1 |
| Application number | US-201414907670-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jul 28, 2014 |
| Priority date | Jul 29, 2013 |
| Publication date | Jun 9, 2016 |
| Grant date | — |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Complexes of agomelatine and sulphonic acids of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
First claim
Opening claim text (preview).
1 - 16 . (canceled) 17 . A complex of agomelatine and sulphonic acids of formula (I): wherein x represents 0 or 1, and RSO 3 H represents 1,5-naphthalenedisulphonic acid or benzenesulphonic acid. 18 . The agomelatine complex according to claim 17 , which is the agomelatine/1,5-naphthalenedisulphonic acid (2/1) complex. 19 . The agomelatine complex according to claim 18 , having the following X-ray powder diffraction diagram expressed in terms of interplanar distance d, Bragg's angle 2 theta (expressed in °±0.2), and relative intensity: 2-Theta (°) exp. d (Å) exp. Intensity (%) 6.3716 13.87229 18.97 11.3804 7.77552 17.98 11.9227 7.42299 36.06 12.5064 7.07784 100.00 12.6590 6.99288 13.75 14.5508 6.08767 44.17 15.5658 5.69292 11.96 16.2029 5.47051 42.63 16.9421 5.23346 25.85 17.6267 5.03171 18.67 19.4300 4.56857 49.04 20.2146 4.39301 22.77 21.4353 4.14550 17.80 21.6713 4.10090 22.84 22.2180 4.00121 64.19 22.4174 3.96607 10.83 24.0749 3.69664 29.61 24.5048 3.63275 13.33 25.1744 3.53763 20.58 25.7599 3.45853 23.59 including the forms whose diffraction angles correspond to within ±0.2°. 20 . The agomelatine complex according to claim 17 , which is the agomelatine/1,5-naphthlenedisulphonic acid (2/1) monohydrate complex. 21 . The agomelatine complex according to claim 20 , having the following X-ray powder diffraction diagram expressed in terms of interplanar distance d, Bragg's angle 2 theta (expressed in °±0.2), and relative intensity: 2-Theta (°) exp. d (Å) exp. Intensity (%) 9.6680 9.14852 12.45 12.4885 7.08796 57.23 12.6164 7.01639 28.61 14.5042 6.10715 57.42 16.2684 5.44863 25.67 16.4624 5.38484 32.93 16.8967 5.24739 90.90 19.3772 4.58091 10.50 22.4767 3.95573 100.00 23.4111 3.79992 20.49 23.5330 3.78051 44.02 23.6735 3.75840 21.92 24.0477 3.70076 13.67 24.5716 3.62303 13.43 25.1240 3.54460 12.46 26.6602 3.34374 19.10 28.1333 3.16930 12.07 28.2443 3.15971 22.49 including, the forms whose diffraction angles correspond to within ±0.2°. 22 . The agomelatine complex according to claim 17 , which is the agomelatine/benzenesulphonic acid (2/1) complex. 23 . The agomelatine complex according to claim 22 , having the following X-ray powder diffraction diagram expressed in terms of interplanar distance d, Bragg's angle 2 theta (expressed in °±0.2), and relative intensity: 2-Theta (°) exp. d (Å) exp. Intensity (%) 8.0711 10.95469 35.25
Assignees
Inventors
Classifications
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US2016159735A1 cover?
- Complexes of agomelatine and sulphonic acids of formula (I): Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
- Who is the assignee on this patent?
- Servier Lab, Shanghai Inst Pharm Industry
- What technology area does this patent fall under?
- Primary CPC classification C07C309/35. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Jun 09 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).