Method of performing an analytical measurement using a mobile device

Patent metadata

Field	Value
Publication number	US-12529657-B2
Application number	US-202318150551-A
Country	US
Kind code	B2
Filing date	Jan 5, 2023
Priority date	Jul 6, 2020
Publication date	Jan 20, 2026
Grant date	Jan 20, 2026

Abstract

A method of performing an analytical measurement includes using a camera of a mobile device to capture a time series of images of at least a part of a medical article. From this, image-derived position information on a relative position of the mobile device and the medical article is derived, thereby generating a first time series of position information. A sensor captures measurement information on the relative position of the mobile device and the medical article. Measurement-derived position information is used to generate a second time series of position information, and the first and second time series of position information are combined to generate an augmented time series of position information. From this, guidance is provided to a user to move the mobile device and the medical article into a relative target position. A mobile device, a kit and a computer program are also disclosed.

First claim

What is claimed is:

1 . A method of performing an analytical measurement using a mobile device having a camera, the method comprising:
i) using the camera to capture a time series of images of at least a part of a medical article; ii) deriving, from the time series of images, image-derived position information on a relative position of the mobile device and the medical article, thereby generating a first time series of position information; iii) using a sensor of the mobile device to capture measurement information on the relative position of the mobile device and the medical article; iv) deriving, from the measurement information alone or in combination with the image-derived position information, measurement-derived position information on the relative position of the mobile device and/or the medical article, thereby generating a second time series of position information; v) generating an augmented time series of position information by combining the first time series of position information and the second time series of position information; and vi) providing guidance to a user, based on the augmented time series of position information, for changing the relative position of the mobile device and the medical article in order to have the user bring the mobile device into a relative target position of the mobile device and the medical article.

2 . The method according to claim 1 , wherein step vi) comprises deriving an item of current position information from the augmented time series of position information and comparing the item of current position information with the relative target position.

3 . The method according to claim 2 , wherein step vi) comprises determining a current point in time and determining whether the current point in time corresponds to a capturing time at which an image of the time series of images is captured, and, if so, using the first time series of position information for deriving the item of current position information, and, if not, using the second time series of position information.

4 . The method according to claim 1 , wherein the relative target position of the mobile device and the medical article comprises a non-parallel relative orientation of the mobile device and the medical article.

5 . The method according to claim 1 , wherein the analytical measurement comprises determining the concentration of an analyte in a sample of a body fluid, wherein the medical article comprises an optical test strip having a reagent test field.

6 . The method according to claim 5 , wherein the medical article further comprises a color reference card comprising at least one of (i) a plurality of different color reference fields having known reference color values and (ii) a plurality of different gray reference fields.

7 . The method according to claim 1 , wherein the first time series comprises image-derived position information as a function of capturing times of the images, wherein the second time series comprises measurement-derived position information as a function of time, wherein the measurement-derived position information of the second time series is given for points in time differing from the capturing times of the images.

8 . The method according to claim 1 , wherein step iv) further comprises using an item of position information from the first time series of position information and estimating an item of measurement-derived position information on the basis of the item of position information from the first time series of position information and at least one item of measurement information captured in step iii).

9 . The method according to claim 8 , wherein the estimating comprises at least one of:
interpolating position information based on image-derived position information derived in step ii) and measurement information captured in step iii); extrapolating position information based on image-derived position information derived in step ii) and measurement information captured in step iii); determining a prospective trajectory of the relative position of the mobile device and the medical article based on the item of position information from the first time series of position information and at least one item of measurement information captured in step iii).

10 . The method according to claim 1 , wherein the user guidance comprises information for the user indicating at least one of (i) a direction into which the mobile device is to be moved in order to achieve the target position, and (ii) an orientation into which the mobile device is to be oriented in order to achieve the target position.

11 . A mobile device, comprising:
a camera; and a sensor configured for capturing position information; wherein the mobile device is configured for performing the method according to claim 1 .

12 . A kit for determining the concentration of an analyte in a body fluid sample, the kit comprising:
the mobile device according to claim 11 ; and the medical article comprising an optical test strip having a reagent test field.

13 . The kit according to claim 12 , further comprising a color reference card that comprises a plurality of different gray reference fields locally assigned to the test field, wherein the color reference card further comprises a plurality of different color reference fields having known reference color values and a plurality of different gray reference fields locally assigned to the color reference fields.

14 . A non-transitory computer readable medium having stored thereon computer-executable instructions for performing the method of claim 1 .

Assignees

• Roche Diabetes Care Inc

Inventors

• Alperowitz Lukas
• Berg Max
• Hailer Fredrik
• Limburg Bernd

Classifications

• G01N2201/0221

  Portable; cableless; compact; hand-held · CPC title

• G01N2021/8488

  the band presenting reference patches · CPC title

• G01N2021/7759

  Dipstick; Test strip · CPC title

• G01N21/78

  producing a change of colour · CPC title

• G06T2207/10024

  Color image · CPC title