Method of treating migraines and headaches
US-11865139-B2 · Jan 9, 2024 · US
Amino acid compositions
US12473261B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12473261-B2 |
| Application number | US-202519030439-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 17, 2025 |
| Priority date | Sep 18, 2007 |
| Publication date | Nov 18, 2025 |
| Grant date | Nov 18, 2025 |
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- Title
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- Abstract
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- First independent claim
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- CPC / IPC classifications
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Abstract
Official abstract text for this publication.
Semisolid supplement compositions are disclosed comprising at least one non-ester nitrate compound and at least one isolated amino acid compound. The at least one isolated amino acid compound is a separate compound than the at least one non-ester nitrate compound. The composition contains at least about 0.05625 mg nitrate ion (NO 3 − ).
First claim
Opening claim text (preview).
We claim: 1 . A semisolid supplement composition comprising: at least one non-ester nitrate compound; and at least one isolated amino acid compound selected from Creatine and Citrulline; wherein the at least one isolated amino acid compound is a separate compound than the at least one non-ester nitrate compound; and wherein the semisolid supplement composition comprises an amount of nitrate ion (NO 3 − ) that is at least about 0.05625 mg. 2 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is least about 0.33125 mg. 3 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is least about 0.33125 mg. 4 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is least about 1 mg. 5 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is least about 1 mg. 6 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is least about 5 mg. 7 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is least about 5 mg. 8 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is least about 10 mg. 9 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is least about 10 mg. 10 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is least about 20 mg. 11 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is least about 20 mg. 12 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is about 0.33125 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ). 13 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is about 0.33125 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ). 14 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is about 1 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ). 15 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is about 1 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ). 16 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the amount of nitrate ion (NO 3 − ) is about 5 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ). 17 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the amount of nitrate ion (NO 3 − ) is about 5 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ). 18 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the semisolid supplement composition comprises one or more of the following: beetroot, spinach, and rocket. 19 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the semisolid supplement composition comprises one or more of the following: beetroot, spinach, and rocket. 20 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the semisolid supplement composition comprises at least one isolated non-ester nitrate compound. 21 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the semisolid supplement composition comprises at least one isolated non-ester nitrate compound. 22 . The composition of claim 1 , wherein the semisolid supplement composition contains a pharmaceutically effective amount of Creatine. 23 . The composition of claim 1 , wherein the semisolid supplement composition contains a pharmaceutically effective amount of Citrulline. 24 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the semisolid supplement composition is ready for distribution to a consumer. 25 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the semisolid supplement composition is ready for distribution to a consumer. 26 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and is isolated from a botanical source. 27 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and is isolated from a botanical source. 28 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Creatine and the at least one non-ester nitrate compound is from a vegetable nitrate source. 29 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Citrulline and the at least one non-ester nitrate compound is from a vegetable nitrate source. 30 . The composition of claim 1 , wherein the amount of nitrate ion (NO 3 − ) is about 5 mg to no more than about 10 mg of nitrate ion (NO 3 − ).
Assignees
Inventors
Classifications
with compounds having an amino group, e.g. acetylcholine, acetylcarnitine · CPC title
Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine · CPC title
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids (hydroxamic acids A61K31/16; peroxy acids A61K31/327) · CPC title
the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid (carnitine A61K31/205) · CPC title
Medicinal preparations containing inorganic active ingredients · CPC title
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Frequently asked questions
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- What does patent US12473261B2 cover?
- Semisolid supplement compositions are disclosed comprising at least one non-ester nitrate compound and at least one isolated amino acid compound. The at least one isolated amino acid compound is a separate compound than the at least one non-ester nitrate compound. The composition contains at least about 0.05625 mg nitrate ion (NO 3 − ).
- Who is the assignee on this patent?
- Thermolife Int Llc
- What technology area does this patent fall under?
- Primary CPC classification C07D233/64. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 18 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 11 related publications on this page (citations in our corpus or others sharing the same primary CPC).