Adsorbates

Patent metadata

Field	Value
Publication number	US-12465064-B2
Application number	US-201917298765-A
Country	US
Kind code	B2
Filing date	Dec 3, 2019
Priority date	Dec 4, 2018
Publication date	Nov 11, 2025
Grant date	Nov 11, 2025

Abstract

The present invention relates to storage stable adsorbates of 3-nitrooxypropanol and derivatives thereof as well as to the production of such adsorbates.

First claim

The invention claimed is:

1 . A method of producing a storage stable adsorbate comprising:
(a) forming a mixture which comprises:
(a1) 1 to 25 wt-%, based on total weight of the adsorbate, of 3-nitrooxypropanol (3-NOP), and
(a2) 5 to 25 wt-%, based on total weight of the adsorbate, of a gelatin, wherein
the 3-NOP and the gelatin are present in amounts to provide a weight ratio (w/w) of the 3-NOP to the gelatin of 0.1 to 1;
(b) applying the mixture of step (a) to at least 30 wt-%, based on total weight of the adsorbate, of a porous precipitated silica carrier, and thereafter (c) allowing at least 50 wt-% of the mixture of step (a) to be adsorbed within internal pores of the silica carrier, wherein the gelatin is present in the mixture in an amount sufficient such that 98.7% to 100% of the 3-NOP is retained within the internal pores of the silica carrier after a storage time of 3 months in a polypropylene container at 25° C. and 50% relative humidity.

2 . The method according to claim 1 , wherein the mixture further comprises (a3) at least one edible solvent selected from the group consisting of propylene glycol, corn oil, rapeseed oil, sunflower oil, middle chain triglyceride (MCT), water, glycerol and combinations thereof.

3 . The method according to claim 2 , wherein the adsorbate comprises, based on the total weight of the adsorbate:
from 5 to 45 wt-% of the at least one edible solvent, and from 0 to 10 wt-%, based on the total weight of the adsorbate, of an additive.

4 . The method according to claim 2 , wherein the mixture consists essentially of (a1) the 3-NOP, (a2) the gelatin and (a3) the edible solvent.

5 . The method according to claim 4 , wherein the edible solvent is propylene glycol or water.

6 . The method according to claim 5 , wherein the adsorbate comprises, based on the total weight of the adsorbate:
(i) 2 to 12 wt-% of the 3-NOP, (ii) 20 to 40 wt-% of the propylene glycol or the water, (iii) from 10 to 18 wt-% of the gelatin, and (vi) at least 40 wt-% of the precipitated silica carrier.

7 . The method according to claim 1 , wherein the gelatin has a bloom value in a range of 0 to 50.

8 . The method according to claim 1 , wherein the weight ratio (w/w) of the 3-NOP to the gelatin is from 0.25 to 0.8.

9 . The method according to claim 1 , wherein the weight ratio (w/w) of the 3-NOP to the gelatin is from 0.3 to 0.7.

10 . The method according to claim 1 , wherein step (c) is practiced such that at least 60 wt. % of the mixture of step (a) is adsorbed within the internal pores of the silica carrier.

11 . The method according to claim 1 , wherein step (c) is practiced such that at least 70 wt. % of the mixture of step (a) is adsorbed within the internal pores of the silica carrier.

12 . The method according to claim 1 , wherein step (c) is practiced such that at least 80 wt. % of the mixture of step (a) is adsorbed within the internal pores of the silica carrier.

Assignees

• Dsm Ip Assets Bv

Inventors

• Vidoni Olivia Brigitte
• Gothscheck Christine
• Urban Kai

Classifications

• A23K50/10

  for ruminants · CPC title

• A23K40/35

  Making capsules specially adapted for ruminants · CPC title

• A23K20/28

  Silicates, e.g. perlites, zeolites or bentonites · CPC title

• A23K20/158

  Fatty acids; Fats; Products containing oils or fats · CPC title

• Y02P60/22

  Methane [CH4], e.g. from rice paddies · CPC title