Stent including anti-migration capabilities

Patent metadata

Field	Value
Publication number	US-12370067-B2
Application number	US-202017082693-A
Country	US
Kind code	B2
Filing date	Oct 28, 2020
Priority date	Oct 29, 2019
Publication date	Jul 29, 2025
Grant date	Jul 29, 2025

Abstract

A medical device for treating a body lumen, such as a medical stent, includes an expandable scaffold configured to shift from a radially collapsed state to a radially expanded state. The stent includes a coating disposed along the outer surface of the expandable scaffold in which a portion of the coating includes a plurality of anti-migration members and one or more preferential separation regions. Each preferential separation region is configured to permit first and second regions of the coating to separate from one another along the preferential separation region therebetween as the expandable scaffold shifts from the radially collapsed state to the radially expanded state.

First claim

What is claimed is:

1. A medical stent for treating a body lumen, comprising:
an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface, wherein the expandable scaffold is configured to shift from a radially collapsed state to a radially expanded state; and
a coating disposed along the outer surface of the expandable scaffold, wherein at least a portion of the coating includes a plurality of anti-migration elements, and wherein the coating further includes a separation region, the separation region positioned between a first region of the coating and a second region of the coating;
wherein the separation region is configured to permit the first region of the coating to separate from the second region of the coating along the separation region therebetween as the expandable scaffold shifts from the radially collapsed state to the radially expanded state, wherein the separation of the first region of the coating from the second region of the coating creates a plurality of apertures in the coating along the separation region, wherein the plurality of apertures shift between a closed configuration when the expandable scaffold is in the radially collapsed state to an open configuration when the expandable scaffold is in the radially expanded state;
wherein the coating comprises a base coating disposed along the expandable scaffold and a micro-pattern coating layer disposed over the base coating, the micro-pattern coating layer being formed from the plurality of anti-migration elements and including a wall, the separation region extending within the wall of the micro-pattern coating layer, wherein at least some of the plurality of apertures in the separation region do not extend through the base coating.

2. The medical stent of claim 1 , wherein the separation region is configured to prevent the coating from separating from the outer surface of the expandable scaffold when the expandable scaffold shifts from the radially collapsed state to the radially expanded state.

3. The medical stent of claim 1 , wherein at least some of the plurality of apertures extend entirely through the wall of the micro-pattern coating layer and the base coating.

4. The medical stent of claim 1 , wherein the wall of the micro-pattern coating layer has a radial thickness defined between an outermost surface of the wall and an outer surface of the base coating, wherein at least some of the plurality of apertures extend only partially through the radial thickness of the wall of the micro-pattern coating layer.

5. The medical stent of claim 1 , wherein the plurality of apertures are aligned along a longitudinal axis of the stent.

6. The medical stent of claim 5 , wherein the alignment of the plurality of apertures of the separation regions create a perforated separation region.

7. The medical stent of claim 1 , wherein the separation region extends continuously along a longitudinal axis of the stent from the first end region to the second end region.

8. The medical stent of claim 7 , wherein the separation region extends linearly along the longitudinal axis of the stent.

9. The medical stent of claim 7 , wherein the preferential separation region extends non-linearly along the longitudinal axis of the stent.

10. The medical stent of claim 1 , wherein the expandable scaffold includes a plurality of interwoven filaments, and wherein the plurality of filaments are arranged to define a plurality of cells therebetween, and wherein the separation region is positioned within one of the plurality of cells.

11. A medical stent for treating a body lumen, comprising:
an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface, wherein the expandable scaffold is configured to shift from a radially collapsed state to a radially expanded state; and
a coating disposed along the outer surface of the expandable scaffold, wherein at least a portion of the coating includes a plurality of anti-migration elements disposed thereon;
wherein the coating further includes a plurality of separation regions, each of the separation regions spaced apart from one another, and wherein each of the separation regions is configured to define an aperture in the coating that shifts from a closed configuration to an open configuration when the expandable scaffold shifts from the radially collapsed state to the radially expanded state;
wherein the coating comprises a base coating disposed along the expandable scaffold and a micro-pattern coating layer disposed over the base coating, the micro-pattern coating layer being formed from the plurality of anti-migration elements and including a wall, the separation region extending within the wall of the micro-pattern coating layer, wherein the aperture in at least some of the plurality of separation regions does not extend through the base coating.

12. The medical stent of claim 11 , wherein each of the separation regions is positioned between a first region of the coating and a second region of the coating, and wherein each of the separation regions is configured to permit the first region of the coating to separate from the second region of the coating along each separation region therebetween as the expandable scaffold shifts from the radially collapsed state to the radially expanded state.

13. The medical stent of claim 11 , wherein each of the plurality of separation regions is configured to prevent the coating from separating from the outer surface of the expandable scaffold when the expandable scaffold shifts from the radially collapsed state to the radially expanded state.

14. The medical stent of claim 11 , wherein the aperture of each of the preferential separation regions extends entirely through the wall of the micro-pattern coating layer.

15. The medical stent of claim 11 , wherein the wall of the micro-pattern coating layer has a radial thickness defined between an outermost surface of the wall and an outer surface of the base coating, wherein the aperture of at least some of the separation regions extends only partially through the radial thickness of the wall of the micro-pattern coating layer.

16. The medical stent of claim 11 , wherein each of the separation regions extends continuously along a longitudinal axis of the stent from the first end region to the second end region.

17. The medical stent of claim 11 , wherein each of the separation regions are spaced apart from one another along a longitudinal axis of the stent.

18. The medical stent of claim 11 , wherein the expandable scaffold includes a plurality of interwoven filaments, and wherein the plurality of filaments are arranged to define a plurality of cells therebetween, and wherein each of the separation regions is positioned within a corresponding cell of the plurality of cells.

19. A medical stent, comprising:
an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface, wherein the expandable scaffold is configured to shift from a radially collapsed state to a radially expanded state, and wherein the expandable scaffold includes a plurality of interwoven filaments defining a plurality of cell openings located therebetween; and
a coating disposed along the outer surface of the expandable scaffold, wherein at least a portion of the coating includes a micro-pattern, the micro-pattern including a plurality of individual spaced-apart anti-migration elements;
wherein the micro-pattern is disposed within the

Assignees

• Boston Scient Scimed Inc

Inventors

• Henchie Travis
• Ryan Shawn

Classifications

• A61F2/0077

  Special surfaces of prostheses, e.g. for improving ingrowth (A61F2/30767 takes precedence) · CPC title

• A61F2210/0076

  multilayered, e.g. laminated structures · CPC title

• A61F2002/825

  having longitudinal struts · CPC title

• A61F2250/0039

  differing in diameter · CPC title

• A61F2250/0026

  differing in surface structures · CPC title