Single container preparation of peritoneal dialysis fluid

Patent metadata

Field	Value
Publication number	US-12329893-B2
Application number	US-202117208251-A
Country	US
Kind code	B2
Filing date	Mar 22, 2021
Priority date	Mar 22, 2021
Publication date	Jun 17, 2025
Grant date	Jun 17, 2025

Abstract

The invention relates to systems and methods for generation and use of peritoneal dialysis fluid. The peritoneal dialysis fluid is generated by dissolving solids or diluting concentrated liquids in a single container having all components of the final peritoneal dialysis fluid.

First claim

What is claimed is:

1. A system, comprising:
a water source;
a dialysate container,
wherein the dialysate container initially contains solid material or a concentrated liquid;

a recirculation line,
wherein the recirculation line has an inlet and an outlet fluidly connected to the dialysate container; and

a control system,
wherein the control system is programmed to pump a predetermined volume or a predetermined mass of water into the dialysate container to generate a peritoneal dialysis fluid.

2. The system of claim 1 , further comprising a water purification module between the water source and the dialysate container.

3. The system of claim 2 , wherein the water purification module comprises one or more selected from the group consisting of a sorbent cartridge, activated carbon, a reverse osmosis module, an electrodialysis module, a carbon filter, and a nanofilter.

4. The system of claim 1 , further comprising a mixing element in the dialysate container.

5. The system of claim 4 , wherein the mixing element comprises a venturi tube in an inlet of the dialysate container.

6. The system of claim 5 , the venturi tube comprising:
a first section distal to an interior portion of the dialysate container, the first section having a first diameter,
a second section distal to the first section and proximal to the interior portion of the dialysate container, the second section having a second diameter smaller than the first diameter forming a constriction, and
a third section distal to the second section and extending inwardly into the interior portion of the dialysate container, the third section having a third diameter larger than the second diameter, and having a suction port exposing an interior of the venturi tube to the interior portion of the dialysate container.

7. The system of claim 1 , further comprising a cycler fluidly connectable to the dialysate container.

8. The system of claim 7 , the control system further programmed to pump a predetermined volume of the peritoneal dialysis fluid into the cycler.

9. The system of claim 7 , further comprising a sterilization module between the dialysate container and the cycler.

10. The system of claim 1 , wherein the solid material or concentrated liquid comprises sodium chloride, calcium chloride, magnesium chloride, sodium lactate, sodium bicarbonate, and an osmotic agent.

11. The system of claim 10 , wherein the osmotic agent is dextrose.

12. The system of claim 1 , wherein the water source is a tap water source.

13. The system of claim 1 , wherein the water source is a purified water source.

14. The system of claim 1 , wherein the dialysate container initially contains the solid material.

15. The system of claim 1 , further comprising at least one sensor in communication with the control system, the control system determining a concentration of at least one solute in the peritoneal dialysis fluid based on data from the at least one sensor.

16. The system of claim 1 , further comprising at least one heater between the water source and the dialysate container.

17. The system of claim 1 , further comprising a heater in the recirculation line.

18. A system, comprising:
a water source;
a dialysate container,
wherein the dialysate container initially contains solid material or a concentrated liquid;
wherein the dialysate container is fluidly connected to an inlet and an outlet of a recirculation line; and

a control system,
wherein the control system is programmed to pump a predetermined volume or a predetermined mass of water into the dialysate container to generate a peritoneal dialysis fluid.

19. The system of claim 18 , further comprising a water purification module between the water source and the dialysate container.

20. The system of claim 19 , wherein the water purification module comprises at least one of a sorbent cartridge, activated carbon, a reverse osmosis module, an electrodialysis module, a carbon filter, a nanofilter, or any combination thereof.

21. The system of claim 18 , further comprising a cycler fluidly connectable to the dialysate container.

22. The system of claim 21 , the control system further programmed to pump a predetermined volume of the peritoneal dialysis fluid into the cycler.

23. The system of claim 21 , further comprising a sterilization module between the dialysate container and the cycler.

24. The system of claim 18 , wherein the solid material or concentrated liquid comprises sodium chloride, calcium chloride, magnesium chloride, sodium lactate, sodium bicarbonate, and an osmotic agent.

25. The system of claim 24 , wherein the osmotic agent is dextrose.

26. The system of claim 18 , wherein the water source is a tap water source.

27. The system of claim 18 , wherein the water source is a purified water.

28. The system of claim 18 , further comprising at least one sensor in communication with the control system, the control system determining a concentration of at least one solute in the peritoneal dialysis fluid based on data from the at least one sensor.

29. The system of claim 28 , further comprising a heater in the recirculation line.

30. The system of claim 18 , further comprising at least one heater between the water source and the dialysate container.

Assignees

• Mozarc Medical Us Llc

Inventors

• Hobot Christopher M
• Meyer Thomas E

Classifications

• A61M1/1694

  with recirculating dialysing liquid · CPC title

• A61M1/1656

  Apparatus for preparing dialysates · CPC title

• A61M1/1696 Primary

  with dialysate regeneration · CPC title

• A61M1/287

  Dialysates therefor · CPC title

• A61M1/1666

  by dissolving solids · CPC title