Sensor and method of sensing for dialysis machine

Patent metadata

Field	Value
Publication number	US-9731059-B2
Application number	US-201313933828-A
Country	US
Kind code	B2
Filing date	Jul 2, 2013
Priority date	Jul 2, 2013
Publication date	Aug 15, 2017
Grant date	Aug 15, 2017

Abstract

A dialysis machine useful in hemodialysis can process or treat a reverse osmosis water flow received through the machine to prepare a dialysate. The machine can include an additive source to introduce an additive, such as bicarbonate, to the reverse osmosis water flow. The machine can include a sensor in fluid communication with the additive introduction point that can measure the conductivity or similar characteristic of the solution. During a first time period when additive is actively introduced to the reverse osmosis water flow, the sensor can measure a relatively high conductivity value. During a second time period when additive is not introduced to the reverse osmosis water flow, the sensor can measure a relatively low conductivity value. The dialysis machine can include a controller that processes these measurements to assist control and operation of the machine.

First claim

The invention claimed is:

1. A method of measuring dialysate characteristics in a dialysis system comprising:
receiving a substantially pure water flow upstream of a mixing chamber;
diverting a portion of the substantially pure water flow through a diverting branch having an additive source to form an additive solution;
mixing the additive solution with the undiverted substantially pure water flow the mixing chamber to form fresh dialysate;
measuring an electrical characteristic of the additive in the fresh dialysate during a first time period using a sensor downstream of the mixing chamber and upstream of an exit port of the dialysis system configured to communicate with a dialyzer;
ceasing introduction of the additive to the diverted portion during a second time period; and
measuring the electrical characteristic of the pure water flow during the second time period using the sensor.

2. The method of claim 1 , further comprising comparing the electrical characteristic of the substantially pure water flow to a predetermined threshold.

3. The method of claim 2 , wherein the sensor is a conductivity cell and the electrical characteristic is conductivity.

4. The method of claim 3 , further comprising:
measuring a conductivity of a mixture of the additive and the substantially pure water flow;
comparing the conductivity of the mixture with the conductivity of the substantially pure water flow; and
determining a quantity of the additive introduced to the substantially pure water flow.

5. The method of claim 3 , wherein the conductivity cell is selected from the group consisting of a two-electrode cell, a three-electrode cell, and a four-electrode cell.

6. The method of claim 1 , wherein the additive is bicarbonate or a bicarbonate solution.

7. The method of claim 1 , further comprising introducing a second additive to the fresh dialysate at a second additive source disposed downstream of the sensor and upstream of the exit port of the dialysis system.

8. A dialysis machine comprising:
a substantially pure water introduction port for receiving a substantially pure water flow from a substantially pure water source;
an additive source for supplying an additive to form an additive solution;
a diverting branch for diverting a portion of the substantially pure water flow to the additive source;
an additive introduction point downstream of the substantially pure water introduction port and fluidly communicating with the additive source;
a mixing chamber proximate the additive introduction pint for mixing the additive solution and the undiverted substantially pure water flow;
a sensor downstream of the mixing chamber and upstream of an exit port of the dialysis machine configured to communicate with a dialyzer; and
a controller electrically communicating with the sensor and including executable instructions to measure an electrical characteristic during a first time period using the sensor when the additive solution is introduced to the substantially pure water flow and to measure the electrical characteristic during a second time period using the sensor when the additive solution is not introduced to the substantially pure water flow.

9. The dialysis machine of claim 8 , wherein the sensor is a conductivity cell and the electrical characteristic is conductivity.

10. The dialysis machine of claim 9 , wherein the conductivity cell is selected from the group consisting of a two-electrode cell, a three-electrode cell, and a four-electrode cell.

11. The dialysis machine of claim 10 , further comprising an additive pump fluidly communicating with the additive source and the additive introduction point.

12. The dialysis machine of claim 11 , wherein the additive pump is in electronic communication with the controller and the controller further includes executable instructions to intermittently and selectively activate the additive pump to introduce the additive to the substantially pure water flow through the additive introduction point.

13. The dialysis machine of claim 12 , wherein the controller further includes executable instructions to compare conductivity during the second time period with a predetermined threshold.

14. The dialysis machine of claim 13 , wherein the controller further includes an executable instruction to compare conductivity during the second time period with conductivity of a mixture of the additive solution and the substantially pure water flow and to compare conductivity of the substantially pure water with a conductivity of the mixture.

15. The dialysis machine of claim 14 , wherein the controller further determines a quantity of the additive introduced into the substantially pure water flow.

16. The dialysis machine of claim 8 , wherein the additive in the additive source is bicarbonate or a bicarbonate solution.

17. A method of controlling a dialysis machine comprising:
directing a substantially pure water flow through the dialysis machine;
selectively diverting a portion of the substantially pure water flow through a diverting branch to an additive source to prepare an additive solution;
intermittently introducing the additive solution to the substantially pure water flow in a mixing chamber and mixing with undiverted substantially pure water flow to prepare fresh dialysate;
measuring a conductivity of the substantially pure water flow with a sensor in fluid communication with the mixing chamber and with an exit port of the dialysis machine configured to communicate with a dialyzer; and
determining a high conductivity value at a first time period and a low conductivity value at a second time period for the substantially pure water flow, wherein the low conductivity value corresponds to the conductivity of the substantially pure water flow absent or substantially absent the additive.

18. The method of claim 17 , further comprising comparing the low conductivity value with a predetermined threshold.

19. The method of claim 17 , further comprising:
measuring a mixture conductivity value of a mixture of the additive and the substantially pure water flow;
comparing the mixture conductivity value with the low conductivity value; and
determining a quantity of the additive introduced into to the substantially pure water flow.

20. The method of claim 17 , wherein the additive is bicarbonate.

Assignees

• Fresenius Medical Care Holdings Inc

Inventors

• Crnkovich Martin
• Wang Aiyuan
• Wang Fei

Classifications

• A61M1/1605

  Physical characteristics of the dialysate fluid · CPC title

• C02F2209/05

  Conductivity or salinity · CPC title

• C02F1/441

  by reverse osmosis · CPC title

• C02F1/008

  Control or steering systems not provided for elsewhere in subclass C02F · CPC title

• A61M2205/3317

  Electromagnetic, inductive or dielectric measuring means · CPC title