Medical leads and techniques for manufacturing the same

Patent metadata

Field	Value
Publication number	US-12318619-B2
Application number	US-202217663601-A
Country	US
Kind code	B2
Filing date	May 16, 2022
Priority date	May 27, 2021
Publication date	Jun 3, 2025
Grant date	Jun 3, 2025

Abstract

In some examples, the disclosure relates to a medical device such as an implantable medical lead. The medical lead may include: a lead body including an electrically conductive lead wire; an electrical contact on a proximal portion of the lead body, the electrical contact including a contact substrate; and an electrode on a distal portion of the lead body, the electrode including an electrode substrate, wherein the electrode substrate is electrically coupled to the contact substrate via the electrically conductive lead wire, wherein the lead wire is formed of a composition comprising titanium or titanium alloys, wherein the electrode substrate is formed of a first beta-titanium alloy, and wherein the contact substrate is formed of a second beta-titanium alloy.

First claim

The invention claimed is:

1. A medical lead comprising:
a lead body including an electrically conductive lead wire;
an electrical contact on a proximal portion of the lead body, the electrical contact comprising a contact substrate; and
an electrode on a distal portion of the lead body, the electrode comprising an electrode substrate,
wherein the electrode substrate is electrically coupled to the contact substrate via the electrically conductive lead wire,
wherein the lead wire is formed of a composition comprising titanium or titanium alloys,
wherein the electrode substrate is formed of a first beta-titanium alloy, wherein the first beta-titanium alloy comprises a TiTaSn alloy, and
wherein the contact substrate is formed of a second beta-titanium alloy.

2. The medical lead of claim 1 , wherein the TiTaSn alloy includes about 46 wt % to about 54 wt % Ta and about 3.5 wt % to about 6.5 wt % Sn.

3. The medical lead of claim 2 , wherein a balance of the TiTaSn alloy is titanium.

4. The medical lead of claim 1 , wherein the electrode substrate and the contact substrate are each attached to the lead wire by at least one of laser welding or resistance welding.

5. The medical lead of claim 1 , further comprising a coating or a laser modified surface layer on an outer surface of the electrode substrate.

6. The medical lead of claim 1 , wherein the lead wire is coated with an electrical insulator, wherein the electrical insulator comprises an SI polyimide.

7. The medical lead of claim 1 , wherein the lead wire, the electrode substrate, and the contact substrate are formed of different compositions.

8. The medical lead of claim 1 , wherein the first beta titanium alloy and the second beta titanium alloy are different alloys.

9. The medical lead of claim 1 , wherein the first beta titanium alloy and the second beta titanium alloy are the same alloys.

10. The medical lead of claim 1 , wherein the electrode comprises a first electrode, the electrical contact comprises a first electrical contact, and the lead wire comprises a first lead wire, the medical lead further comprising a second electrode on the distal portion of the lead body, a second electrical contact on the proximal portion of the lead body, and a second lead wire, and wherein a second electrode substrate of the second electrode is electrically coupled to a second contact substrate of the second contact via the second lead wire, wherein the second electrode is positioned at a different axial position of the lead body than the first electrode, and wherein the second electrode substrate is formed of the first beta-titanium alloy and the second contact substrate is formed of the second beta-titanium alloy.

11. The medical lead of claim 1 , wherein the lead wire is formed of a third beta titanium alloy.

12. The medical lead of claim 11 , wherein the third beta titanium alloy is different than at least one of the first beta titanium alloy or the second beta titanium alloy.

13. A medical device comprising a medical lead, the medical lead comprising:
a lead body including an electrically conductive lead wire;
an electrical contact on a proximal portion of the lead body, the electrical contact comprising a contact substrate; and
an electrode on a distal portion of the lead body, the electrode comprising an electrode substrate,
wherein the electrode substrate is electrically coupled to the contact substrate via the electrically conductive lead wire,
wherein the lead wire is formed of a composition comprising titanium or titanium alloys,
wherein the electrode substrate is formed of a first beta-titanium alloy, wherein the contact substrate is formed of a second beta-titanium alloy, and
wherein the second beta alloy comprises a Ti-15Mo alloy.

14. The medical device of claim 13 , wherein the Ti-15Mo alloy comprises a Ti15Mo5Zr3Al alloy.

15. The medical device of claim 13 , further comprising a medical device including an electrical stimulation generator, wherein the medical lead is configured to be electrically coupled to the stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator to the electrode substrate via the lead wire and the contact substrate.

16. A medical device comprising a medical lead, the medical lead comprising:
a lead body including an electrically conductive lead wire;
an electrical contact on a proximal portion of the lead body, the electrical contact comprising a contact substrate; and
an electrode on a distal portion of the lead body, the electrode comprising an electrode substrate,
wherein the electrode substrate is electrically coupled to the contact substrate via the electrically conductive lead wire,
wherein the lead wire is formed of a composition comprising titanium or titanium alloys,
wherein the electrode substrate is formed of a first beta-titanium alloy,

wherein the contact substrate is formed of a second beta-titanium alloy, and
wherein the first beta Ti alloy has at least one of an ultimate tensile strength (UTS) of greater than about 110 kilopounds per square inch (ksi), an elongation of greater than about 12%, an elastic modulus of less than about 11000 ksi, an alpha phase volume fraction of less than about 4 percent, or a grain size of less than 20 micrometers.

17. The medical device of claim 16 , further comprising a medical device including an electrical stimulation generator, wherein the medical lead is configured to be electrically coupled to the stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator to the electrode substrate via the lead wire and the contact substrate.

18. A medical device comprising:
a medical lead comprising
a lead body including an electrically conductive lead wire;
an electrical contact on a proximal portion of the lead body, the electrical contact comprising a contact substrate; and
an electrode on a distal portion of the lead body, the electrode comprising an electrode substrate,
wherein the electrode substrate is electrically coupled to the contact substrate via the electrically conductive lead wire,
wherein the lead wire is formed of a composition comprising titanium or titanium alloys,
wherein the electrode substrate is formed of a first beta-titanium alloy, and
wherein the contact substrate is formed of a second beta-titanium alloy, wherein the lead wire, the electrode substrate, and the contact substrate are formed of different compositions; and

a medical device including an electrical stimulation generator, wherein the medical lead is configured to be electrically coupled to the stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator to the electrode substrate via the lead wire and the contact substrate.

Assignees

• Medtronic Inc

Inventors

• Li Bernard Q
• Stone Richard T
• Shi Alan
• Humphrys Seth M
• Tan Wen
• Stepka Nicholas D

Classifications

• C22F1/183

  of titanium or alloys based thereon · CPC title

• C22C14/00

  Alloys based on titanium · CPC title

• A61N1/0551

  Spinal or peripheral nerve electrodes · CPC title

• A61N1/36125

  Details of circuitry or electric components · CPC title

• A61N1/375 Primary

  Constructional arrangements, e.g. casings · CPC title