Medical leads and techniques for manufacturing the same

Patent metadata

Field	Value
Publication number	US-10406349-B2
Application number	US-201414206650-A
Country	US
Kind code	B2
Filing date	Mar 12, 2014
Priority date	Mar 15, 2013
Publication date	Sep 10, 2019
Grant date	Sep 10, 2019

Abstract

In some examples, the disclosure relates to a medical device comprising a lead including an electrically conductive lead wire; and an electrode electrically coupled to the lead wire, the electrode including a substrate and a coating on an outer surface of the substrate, wherein the lead wire is formed of a composition comprising titanium or titanium alloys, wherein the substrate is formed of a composition comprising one or more of titanium, tantalum, niobium, and alloys thereof, wherein the coating comprises at least one of Pt, TiN, IrOx, and poly(dioctyl-bithiophene) (PDOT). In some examples, the lead wire may be coupled to the lead wire via a weld, such as, e.g., a laser weld.

First claim

The invention claimed is:

1. A medical device comprising:
a lead including an electrically conductive lead wire; and
an electrode electrically coupled to the lead wire, the electrode including a substrate and a coating on an outer surface of the substrate, wherein the lead wire is formed of a composition comprising titanium or titanium alloy, wherein the substrate is formed of a composition comprising one or more of titanium, tantalum, niobium, or an alloy thereof, wherein the coating comprises at least one of Pt, TiN, IrOx, or poly(dioctyl-bithiophene) (PDOT).

2. The medical device of claim 1 , wherein the lead wire and substrate are formed of different compositions.

3. The medical device of claim 1 , wherein the coating defines a thickness of between approximately 0.5 micrometers and approximately 15 micrometers.

4. The medical device of claim 1 , wherein the composition of the lead wire comprises the titanium alloy, wherein the titanium alloy includes titanium and molybdenum.

5. The medical device of claim 1 , wherein the coating is deposited on the outer surface of the substrate via sputter depositing to increase the effective surface area of the outer surface of the substrate.

6. The medical device of claim 1 , wherein the electrode is one of a ring electrode or segmented electrode.

7. The medical device of claim 1 , wherein the electrode exhibits a charge storage capacity of greater than approximately 50 mC/cm 2 .

8. The medical device of claim 1 , wherein the lead wire and substrate are formed of substantially a same composition.

9. The medical device of claim 1 , wherein the lead wire and the substrate are coupled to each other via a laser weld or resistance weld.

10. The medical device of claim 1 , further comprising a medical device including an electrical stimulation generator, wherein the lead wire is configured to be electrically coupled to the stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator through the coating on the substrate via the lead wire.

11. A method for forming a medical device lead, the method comprising:
electrically coupling a lead including an electrically conductive lead wire to an electrode, the electrode comprising a substrate having an outer surface; and
depositing a coating on the outer surface of the substrate, wherein the lead wire is formed of a composition comprising titanium or titanium alloy, wherein the substrate is formed of a composition comprising one or more of titanium, tantalum, niobium, or an alloy thereof, wherein the coating comprises at least one of Pt, TiN, IrOx, or poly(dioctyl-bithiophene) (PDOT).

12. The method of claim 11 , wherein the lead wire and substrate are formed of different compositions.

13. The method of claim 11 , wherein the coating defines a thickness of between approximately 0.5 micrometers and approximately 15 micrometers.

14. The method of claim 11 , wherein the composition of the lead wire comprises the titanium alloy, wherein the titanium alloy comprises titanium and molybdenum.

15. The method of claim 11 , wherein the coating is deposited on the outer surface of the substrate via sputter depositing to increase the effective surface area of the outer surface of the substrate.

16. The method of claim 11 , wherein the electrode is one of a ring electrode or segmented electrode.

17. The method of claim 11 , wherein the electrode exhibits a charge storage capacity of greater than approximately 50 mC/cm 2 .

18. The method of claim 11 , wherein the lead wire and substrate are formed of substantially a same composition.

19. The method of claim 11 , wherein the lead wire and the substrate are coupled to each other via a laser weld or a resistance weld.

20. The method of claim 11 , further comprising a medical device including an electrical stimulation generator, wherein the lead wire is configured to be electrically coupled to the stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator through the coating on the substrate via the lead wire.

21. The medical device of claim 1 , wherein the coating comprises at least one of TiN, IrOx, or PDOT.

22. The medical device of claim 1 , wherein the lead wire extends distally within the lead from a proximal end of the lead to the electrode, and wherein the lead wire is configured to electrically couple the electrode to an electrical stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator through the coating on the substrate via the lead wire.

23. The medical device of claim 1 , wherein the electrode comprises a first electrode, the substrate comprises a first substrate, and the coating comprises a first coating, wherein the lead further includes a second electrically conductive lead wire electrically isolated from the first electrically conductive lead wire, the medical device further comprising a second electrode electrically coupled to the second electrically conductive lead wire, wherein the second electrode comprises a second substrate and a second coating on an outer surface of the second substrate, wherein the second electrically conductive lead wire is formed of a second composition comprising titanium or titanium alloy, wherein the second substrate is formed of a second composition comprising one or more of titanium, tantalum, niobium, or an alloy thereof, and wherein the second coating comprises at least one of Pt, TiN, IrOx, or poly(dioctyl-bithiophene) (PDOT).

24. The medical device of claim 23 , wherein the first substrate is disposed at a location on the lead distal to a location of the second substrate.

25. The medical device of claim 23 , wherein the first electrode and the second electrode each extend distally to substantially a same length from a proximal end of the lead.

26. The method of claim 11 , wherein the coating comprises at least one of TiN, IrOx, or PDOT.

27. The method of claim 11 , wherein the lead wire extends distally within the lead from a proximal end of the lead to the electrode, and wherein the lead wire is configured to electrically couple the electrode to an electrical stimulation generator such that electrical stimulation signals may be transmitted from the electrical stimulation generator through the coating on the substrate via the lead wire.

28. The method of claim 11 , wherein the electrode comprises a first electrode, the substrate comprises a first substrate, and the coating comprises a first coating, and wherein the second electrically conductive lead wire is electrically isolated from the first electrically conductive lead wire, the method further comprising:
electrically coupling the lead to a second electrode by coupling a second electrically conductive lead wire to the second electrode, the second electrode comprising a second substrate having an outer surface; and
depositing a second coating on the outer surface of the second substrate, wherein the second electrically conductive lead wire is formed of a composition comprising titanium or titanium alloy, wherein the second substrate is formed of a composition comprising one or more of titanium, tantalum, niobium, or an alloy thereof, and wherein the second coating comprises at least one of Pt, TiN, IrOx, or poly(dioctyl-bithiophene) (PDOT).

Assignees

• Medtronic Inc

Inventors

• Shi Alan
• Janzig Darren A
• Li Bernard Q
• Stone Richard T
• Seeley Dale F
• Cong Peng

Classifications

• A61N1/05 Primary

  for implantation or insertion into the body, e.g. heart electrode (A61N1/06 takes precedence) · CPC title

• A61N1/375

  Constructional arrangements, e.g. casings · CPC title