Mitral valve annular dilation devices and methods for use

Patent metadata

Field	Value
Publication number	US-12272264-B2
Application number	US-202217672606-A
Country	US
Kind code	B2
Filing date	Feb 15, 2022
Priority date	Aug 20, 2019
Publication date	Apr 8, 2025
Grant date	Apr 8, 2025

Abstract

A dilation device is provided for modeling mitral regurgitation in a mitral valve that includes an annular housing surrounding an aperture; a first anterior blade mounted to the housing and defining a substantially straight inner edge adjacent the aperture; and a plurality of posterior blades mounted to the housing and defining a curved inner edge adjacent the aperture, the posterior blades movable to dilate a valve mounted to the blades. An annulus of a valve may be sutured to the blades such that valve is disposed adjacent the aperture, and the dilation device may be actuated to cause the posterior blades to dilate a posterior region of the valve.

First claim

What is claimed is:

1. A dilation device for modeling mitral regurgitation in a mitral valve, comprising:
an annular housing surrounding an aperture;
an anterior blade mounted to the housing and defining an inner edge adjacent the aperture;
a plurality of posterior blades mounted to the housing and defining an inner edge adjacent the aperture, the posterior blades movable to dilate a valve mounted to the blades.

2. The dilation device of claim 1 , wherein the inner edge of the anterior blade is substantially straight, and the inner edge of the plurality of posterior blades defines a substantially circular curve.

3. The dilation device of claim 1 , further comprising a plurality of perforations along the respective inner edges of the anterior blade and the plurality of posterior blades for receiving sutures to secure a valve to the anterior blade and the posterior blades.

4. The dilation device of claim 1 , wherein the housing comprises a pivot plate movable relative to a base plate, and wherein each of the posterior blades comprises a first end coupled to the pivot plate such that movement of the pivot plate causes the posterior blades to move between a relaxed position and a dilating position.

5. The dilation device of claim 4 , wherein the base plate comprises a plurality of slots, and each of the posterior blades comprises a second end coupled to a respective slot in the base plate such that the second end moves radially inward and outward when the pivot plate moves.

6. The dilation device of claim 5 , wherein the pivot plate is rotatable relative to the base plate to cause the posterior blades to move radially outward to dilate an anterior annulus of a mitral valve mounted to the posterior blades.

7. The dilation device of claim 4 , further comprising a biasing mechanism coupled to the posterior blades which biases the posterior blades toward the dilating position.

8. The dilation device of claim 7 , wherein the biasing mechanism is a spring coupled to the pivot plate.

9. The dilation device of claim 1 , wherein the anterior blade and posterior blades are laterally flexible to allow the anterior blade and posterior blades to flex laterally to allow substantially natural motion of a mitral valve during a cardiac cycle of a mitral valve.

10. A system for modeling mitral regurgitation in a mitral valve, comprising:
a dilation device comprising an annular housing surrounding an aperture; a first anterior blade mounted to the housing and defining a substantially straight inner edge adjacent the aperture; and a plurality of posterior blades mounted to the housing and defining a curved inner edge adjacent the aperture, the posterior blades movable to dilate a valve mounted to the blades; and
a heart simulator comprising a housing for mounting the dilation device at a location corresponding to a mitral valve of a heart; and a pump for directing fluid through the housing such that the fluid passes through a valve mounted to the dilation device.

11. A method for modeling mitral regurgitation in a mitral valve, comprising:
providing a dilation device comprising an annular housing surrounding an aperture; a first anterior blade mounted to the housing and defining a substantially straight inner edge adjacent the aperture; and a plurality of posterior blades mounted to the housing and defining a curved inner edge adjacent the aperture, the posterior blades movable to dilate a valve mounted to the blades;
securing an annulus of a valve to the blades of the dilation device such that valve is disposed within the aperture; and
actuating the dilation device to cause the posterior blades to dilate a posterior region of the annulus.

12. The method of claim 11 , wherein securing the annulus comprises directing one or more sutures through perforations along the inner edge and the annulus.

13. The method of claim 11 , wherein, during actuation of the dilation device, an anterior region of the annulus does not dilate substantially.

14. The method of claim 11 , further comprising:
mounting the dilation device with the valve secured thereto within a heart simulator; and
directing fluid through the simulator such that the fluid passes through a valve mounted to the dilation device to simulate operation of the valve.

15. The method of claim 14 , wherein the dilation device is actuated to sequentially increase the amount of posterior dilation of the valve to analyze mitral regurgitation.

16. A dilation device for modeling mitral regurgitation in a mitral valve, comprising:
a base plate having a plate aperture and a recess surrounding the aperture;
a mounting ring having a ring aperture, the mounting ring mounted in the recess of the base plate with the ring aperture aligned with the plate aperture;
a plurality of adjustment pins mounted on the base plate spaced angularly around the mounting ring, each of the adjustment pins configured to receive a respective adjustment cord attachable to a valve mounted on the mounting ring and adjustable to selectably dilate the valve.

17. The dilation device of claim 16 , wherein the adjustment pins each comprise a tuning key, each tuning key having a rotatable knob coupled to a rotatable post via a gear set such that rotation of the knob rotates the post, the post for receiving a respective adjustment cord.

18. The dilation device of claim 17 , wherein the gear set comprises a worm gear and a mating pinion gear.

19. The dilation device of claim 16 , wherein the mounting ring is formed of a pliable, elastomeric material for receiving sutures to secure a valve to the mounting ring.

20. The dilation device of claim 16 , further comprising a plurality of biasing mechanisms, each of the biasing mechanisms coupled to a respective adjustment cord.

Assignees

• Univ Leland Stanford Junior

Inventors

• Woo Y Joseph
• Paulsen Michael John
• Paullin Cole C
• Imbrie-Moore Annabel M
• Bandy-Vizcaino Tabitha Marie

Classifications

• G09B23/303

  specially adapted to simulate circulation of bodily fluids · CPC title

• A61B2090/064

  for measuring force, pressure or mechanical tension · CPC title

• A61B2017/00725

  Calibration or performance testing · CPC title

• A61F2/2472

  Devices for testing · CPC title

• A61F2250/001

  for adjusting a diameter · CPC title