Simulated environment for transcatheter heart valve repair

Patent metadata

Field	Value
Publication number	US-9539094-B2
Application number	US-201414195231-A
Country	US
Kind code	B2
Filing date	Mar 3, 2014
Priority date	Mar 13, 2013
Publication date	Jan 10, 2017
Grant date	Jan 10, 2017

Abstract

An apparatus for applying liquid pressure to resected tissue may include a fixture, a papillary assembly coupled to the fixture and having first and second spaced apart papillary attachment elements, and a resected mitral valve attached to the fixture. The fixture may have a first chamber, a second chamber, and an internal panel extending between the first and second chambers. The resected mitral valve may be attached to the internal panel and may have a posterior leaflet, an anterior leaflet, and tendinae chordae. The tendinae chordae may each be attached at a first end to the posterior leaflet or the anterior leaflet and at a second end to one of the papillary attachment elements. A first group of the tendinae chordae may be attached to the first papillary attachment element, and a second group of the tendinae chordae may be attached to the second papillary attachment element.

First claim

The invention claimed is:

1. A simulation apparatus for mounting resected tissue, the apparatus comprising:
a fixture having a first chamber, a second chamber, and an internal panel extending between the first and second chambers, the fixture having at least one introducer configured to receive an elongated catheter assembly therethrough;
a papillary assembly coupled to the fixture and having first and second spaced apart papillary attachment elements, each papillary attachment element being movable relative to the internal panel in at least one degree of freedom; and
a resected mitral valve attached to the internal panel and having a posterior leaflet, an anterior leaflet, and tendinae chordae, the tendinae chordae each attached at a first end to the posterior leaflet or the anterior leaflet and at a second end to one of the papillary attachment elements,
wherein a first group of the tendinae chordae are attached to the first papillary attachment element, and a second group of the tendinae chordae are attached to the second papillary attachment element.

2. The apparatus as claimed in claim 1 , wherein each papillary attachment element is movable relative to the internal panel in six degrees of freedom.

3. The apparatus as claimed in claim 1 , wherein each papillary attachment element includes a suture plate, and wherein the tendinae chordae are each attached to the papillary attachment elements through a resected portion of a papillary muscle.

4. The apparatus as claimed in claim 1 , wherein the fixture further includes first and second side panels disposed at opposite sides of the internal panel, and wherein the first and second papillary attachment elements each have a control rod extending through the respective first and second side panels.

5. The apparatus as claimed in claim 1 , wherein the papillary attachment elements are each at least partially disposed inside the first chamber, and wherein a portion of the introducer is in fluid communication with the first chamber.

6. The apparatus as claimed in claim 1 , wherein the papillary attachment elements are each at least partially disposed inside the first chamber, and wherein a portion of the introducer is in fluid communication with the second chamber.

7. The apparatus as claimed in claim 1 , further comprising a pumping system configured to provide liquid flow through the resected mitral valve.

8. The apparatus as claimed in claim 7 , wherein the papillary attachment elements are each at least partially disposed inside the first chamber, and wherein the pumping system is configured to alternatingly provide high pressure liquid flow into the first chamber and low pressure liquid flow into the second chamber.

9. The apparatus as claimed in claim 8 , wherein the fixture includes an outlet port in fluid communication with the first chamber and the pumping system.

10. The apparatus as claimed in claim 9 , wherein the outlet port includes an artificial aortic valve.

11. A simulation apparatus for mounting resected tissue, the apparatus comprising:
a fixture having a first chamber, a second chamber, and an internal panel extending between the first and second chambers, the fixture having at least one introducer configured to receive an elongated catheter assembly therethrough, the internal panel having an opening extending therethrough between the first and second chambers, the internal panel being configured to receive a resected mitral valve attached thereto and in fluid communication with the opening; and
a papillary assembly coupled to the fixture and having first and second spaced apart papillary attachment elements, each papillary attachment element being movable relative to the internal panel in at least one degree of freedom, each papillary attachment element configured to have tendinae chordae of the resected mitral valve attached thereto.

12. The apparatus as claimed in claim 11 , wherein each papillary attachment element is movable relative to the internal panel in six degrees of freedom.

13. The apparatus as claimed in claim 11 , wherein each papillary attachment element includes a suture plate configured to have the tendinae chordae of the resected mitral valve attached thereto through a resected portion of a papillary muscle.

14. The apparatus as claimed in claim 11 , wherein the fixture further includes first and second side panels disposed at opposite sides of the internal panel, and wherein the first and second papillary attachment elements each have a control rod extending through the respective first and second side panels.

15. A method of mounting resected tissue to a simulation apparatus, the method comprising:
coupling a resected mitral valve to an internal panel extending between first and second chambers of a fixture, the resected mitral valve having a posterior leaflet, an anterior leaflet, and tendinae chordae each attached at a first end to the posterior leaflet or the anterior leaflet;
attaching a second end of each of the tendinae chordae to one of first and second spaced apart papillary attachment elements, such that a first group of the tendinae chordae are attached to the first papillary attachment element, and a second group of the tendinae chordae are attached to the second papillary attachment element;
moving at least one of the first and second papillary attachment elements relative to the internal panel in at least one degree of freedom;
inserting an elongated catheter assembly into at least one of the first and second chambers through an introducer.

16. The method as claimed in claim 15 , further comprising using the elongated catheter assembly to install a clip onto at least one of the posterior and anterior leaflets of the resected mitral valve.

17. The method as claimed in claim 16 , wherein the papillary attachment elements are each at least partially disposed inside the first chamber, and wherein the inserting step includes inserting the elongated catheter assembly into the first chamber through the introducer, such that the clip is delivered to the resected mitral valve through the first chamber.

18. The method as claimed in claim 16 , wherein the papillary attachment elements are each at least partially disposed inside the first chamber, and wherein the inserting step includes inserting the elongated catheter assembly into the second chamber through the introducer, such that the clip is delivered to the resected mitral valve through the second chamber.

19. The method as claimed in claim 15 , wherein the attaching step includes attaching each of the tendinae chordae to the papillary attachment elements through a resected portion of a papillary muscle.

20. The method as claimed in claim 15 , wherein the moving step includes moving first and second control rods of the respective first and second papillary attachment elements, the first and second control rods extending through respective first and second side panels of the fixture disposed at opposite sides of the internal panel.

21. The method as claimed in claim 15 , further comprising pumping liquid through the resected mitral valve.

22. The method as claimed in claim 21 , further comprising, during the pumping step, using the elongated catheter assembly to install a clip onto at least one of the posterior and anterior leaflets of the resected mitral valve.

23. The method as claimed in claim 21 , wherein the papillary attachment elements are each at least partially disposed inside the first chamber, and wherein the

Assignees

• St Jude Medical Cardiology Div Inc

Inventors

• Dale Theodore Paul
• Chalekian Aaron J
• Kurk James Leo

Classifications

• A61B17/00234

  for minimally invasive surgery (A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence) · CPC title

• A61B2017/00349

  Needle-like instruments having hook or barb-like gripping means, e.g. for grasping suture or tissue (A61B17/06066 takes precedence) · CPC title

• A61F2/2466

  Delivery devices therefor · CPC title

• A61F2/2472 Primary

  Devices for testing · CPC title

• A61B17/0644

  penetrating the tissue, deformable to closed position · CPC title