Transcutaneous sensor with dual electrodes and methods of detecting and compensating for withdrawal of a transcutaneous sensor from a patient

Patent metadata

Field	Value
Publication number	US-12268500-B2
Application number	US-202418429826-A
Country	US
Kind code	B2
Filing date	Feb 1, 2024
Priority date	Oct 30, 2017
Publication date	Apr 8, 2025
Grant date	Apr 8, 2025

Abstract

A transcutaneous sensor configured to measure one or more physiological conditions of a patient. The transcutaneous sensor includes a substrate and first and second working electrodes on the substrate. The first working electrode includes a first active sensing area and the second working electrode includes a second active sensing area. The first active sensing area of the first working electrode is longitudinally offset along the substrate from the second active sensing area of the second working electrode.

First claim

What is claimed is:

1. A method of detecting withdrawal of a transcutaneous sensor from a patient, the method comprising:
transducing, with a first working electrode having a first active sensing area and a second working electrode having a second active sensing area of the transcutaneous sensor, an analyte in the patient into a first current output and a second current output;
determining that the transcutaneous sensor has at least partially withdrawn from the patient based on a current ratio of the first current output to the second current output being different than a size ratio of a first size of the first active sensing area to a second size of the second active sensing area.

2. The method of claim 1 , further comprising compensating for a reduction in the current output from one of the first and second working electrodes due to the partial withdrawal of the transcutaneous sensor using a difference between the current ratio and the size ratio.

3. The method of claim 1 , wherein the first size of the first active sensing area is different than the second size of the second active sensing area.

4. The method of claim 1 , wherein the first size of the first active sensing area is substantially equal to the second size of the second active sensing area.

5. A transcutaneous sensing system, comprising:
a transcutaneous sensor comprising:
a substrate;
a first working electrode on the substrate, the first working electrode comprising a first active sensing area configured to transduce an analyte in a patient into a first current output; and
a second working electrode on the substrate, the second working electrode comprising a second active sensing area configured to transduce the analyte in the patient into a second current output; and

a processor configured to determine that the transcutaneous sensor has been at least partially withdrawn from the patient in response to a current ratio of the first current output to the second current output being different than a size ratio of a first size of the first active sensing area to a second size of the second active sensing area.

6. The system of claim 5 , wherein the data processing unit is further configured to compensate for a reduction in the first current output or the second current output due to the partial withdrawal of the transcutaneous sensor utilizing a difference between the current ratio and the size ratio.

7. The system of claim 5 , wherein the first size of the first active sensing area is different than the second size of the second active sensing area.

8. The system of claim 5 , wherein the first size of the first active sensing area and the second size of the second active sensing area are substantially equal in size.

9. The system of claim 5 , wherein the first active sensing area comprises a first plurality of sensing spots and wherein the second active sensing area comprises a second plurality of sensing spots.

10. The system of claim 9 , wherein a size of each sensing spot of the first plurality of sensing spots is substantially the same as a size of each sensing spot of the second plurality of sensing spots.

11. The system of claim 10 , wherein the first plurality of sensing spots comprises a greater number of sensing spots than the second plurality of sensing spots.

12. The system of claim 5 , wherein a proximalmost end of the first active sensing area is spaced apart from a distal end of the substrate by a first distance and a proximalmost end of the second active sensing area is spaced apart from the distal end of the substrate by a second distance different than the first distance.

13. The system of claim 5 , wherein a distalmost end of the first active sensing area is spaced apart from a distal end of the substrate by a first distance and a distalmost end of the second active sensing area is spaced apart from the distal end of the substrate by a second distance different than the first distance.

14. The system of claim 5 , wherein a longitudinally centered portion of the first active sensing area is offset from a longitudinally centered portion of the second active sensing area.

15. An analyte monitoring system comprising:
a transcutaneous sensor comprising:
a substrate;
a first working electrode on the substrate, the first working electrode comprising a first active sensing area configured to transduce an analyte in the patient into a first current output; and
a second working electrode on the substrate, the second working electrode comprising a second active sensing area configured to transduce the analyte in the patient into a second current output,
wherein the first active sensing area is longitudinally offset along the substrate from the second active sensing area; and

a data processing unit coupled to the transcutaneous sensor, wherein the data processing unit is configured to:
determine a current ratio of the first current output to the second current output;
compare the current ratio to a size ratio defined by a first size of the first active sensing area to a second size of the second active sensing area; and
determine that the transcutaneous sensor has been at least partially withdrawn from the patient in response to the current ratio being different than the size ratio; and

a primary receiver unit coupled to the data processing unit.

16. The analyte monitoring system of claim 15 , further comprising a secondary receiver unit coupled to the data processing unit.

17. The analyte monitoring system of claim 15 , further comprising a data processing terminal, wherein the primary receiver unit is configured to transmit data to the data processing terminal.

18. The analyte monitoring system of claim 15 , wherein the transcutaneous sensor further comprises a reference electrode on the substrate.

19. The analyte monitoring system of claim 18 , wherein the transcutaneous sensor further comprises a counter electrode on the substrate.

20. The analyte monitoring system of claim 19 , wherein the transcutaneous sensor further comprises a first dielectric insulator layer between the reference electrode and the substrate and a second dielectric insulator layer between the counter electrode and the substrate.

Assignees

• Abbott Diabetes Care Inc

Inventors

• Feldman Benjamin

Classifications

• A61B5/14532

  for measuring glucose, e.g. by tissue impedance measurement · CPC title

• A61B5/14865 Primary

  invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors · CPC title