Methods for mixing a fluid with foldable impellers

Patent metadata

Field	Value
Publication number	US-12226743-B2
Application number	US-202218060728-A
Country	US
Kind code	B2
Filing date	Dec 1, 2022
Priority date	Apr 6, 2012
Publication date	Feb 18, 2025
Grant date	Feb 18, 2025

Abstract

A method of mixing a fluid includes at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line or drive shaft and an impeller secured to the drive line or drive shaft, the impeller including a plurality of impeller blades that are pivotable relative to the drive line or drive shaft, at least one of the plurality of impeller blades being in a collapsed position. A fluid is delivered into the compartment of the collapsible bag. The drive line or drive shaft is then rotated so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment.

First claim

What is claimed is:

1. A method of mixing a fluid, the method comprising:
at least partially unfolding a collapsible bag bounding a compartment, the collapsible bag containing in the compartment at least a portion of an elongated drive line and an impeller secured to the drive line, the impeller including a plurality of impeller blades that are pivotable relative to the drive line, at least one of the plurality of impeller blades being in a collapsed position, and at least a portion of the length of the drive line being flexible;
delivering a fluid into the compartment of the collapsible bag; and
rotating the drive line so as to rotate the impeller within the compartment and mix the fluid therein, the at least one of the plurality of impeller blades pivoting from the collapsed position to an expanded position as the impeller is rotated within the compartment,
wherein the drive line is at least partially disposed within the compartment of the collapsible bag, wherein at least 30% of the drive line within the compartment is sufficiently flexible that it can be twisted under torsion over an angle of at least 45° without plastic deformation, and the drive line is comprised of a flexible cable, cord or a single solid core line.

2. The method as recited in claim 1 , wherein the impeller comprises a hub secured to the drive line, each of the plurality of impeller blades being pivotably coupled to the hub.

3. The method as recited in claim 1 , wherein the impeller comprises a hub secured to the drive line and a flange radially outwardly projecting from the hub, the hub having a central longitudinal axis extending therethrough, each of the plurality of impeller blades being pivotably coupled to the flange.

4. The method as recited in claim 3 , further comprising a retainer at least partially encircling the hub and being secured to the flange, each of the plurality of impeller blades being pivotably secured between the flange and the retainer.

5. The method as recited in claim 4 , wherein the flange and the retainer both completely encircle the hub.

6. The method as recited in claim 3 , wherein each of the plurality of impeller blades comprise:
an elongated arm longitudinally extending between a first end and an opposing second end, the first end being pivotably coupled to the flange so that the elongated arm pivots about a rotational axis, the rotational axis being disposed parallel to the central longitudinal axis of the hub; and
an enlarged blade head disposed at the second end of the elongated arm.

7. The method as recited in claim 1 , wherein each of the plurality of impeller blades are pivotable between a collapsed position and an expanded position, each of the impeller blades having a terminal tip that is closer to the drive line when the impeller blades are in the collapsed position than when in the expanded position.

8. The method as recited in claim 7 , wherein each of the plurality of blades are mechanically stopped when moved to the collapsed position and the expanded position.

9. The method as recited in claim 1 , wherein the collapsible bag is comprised of one or more sheets of polymeric film.

10. The method as recited in claim 1 , further comprising coupling a drive shaft to the drive line such that rotation of the drive shaft outside of the collapsible bag facilitates rotation of the drive line within the collapsible bag.

11. The method as recited in claim 1 , wherein the drive line has a length extending between a first end rotatably connected to a first end of the collapsible bag and a second end rotatably connected to a second end of the collapsible bag.

12. The method as recited in claim 1 ,
wherein the elongated drive line is operationally coupled to a drive shaft, the drive shaft being at least partially disposed within the compartment of the collapsible bag; and
wherein a seal seals the drive shaft to the collapsible bag.

13. The method as recited in claim 1 , further comprising positioning the collapsible bag within a chamber of a support housing, the support housing having a floor and a sidewall upstanding from the floor.

14. The method as recited in claim 13 , further comprising securing the collapsible bag to the floor of the support housing.

15. The method of claim 1 ,
wherein the flexible cable is comprised of a plurality of strands.

Assignees

• Life Technologies Corp

Inventors

• Staheli Clinton C
• Knudsen Brandon M
• Williams Trevor G
• Kjar Steven R

Classifications

• B01F35/4121

  at the top and at the bottom of the receptacle, e.g. for performing a conical orbital movement about a vertical axis · CPC title

• B01F35/4111

  at the top of the receptacle · CPC title

• B01F35/513

  Flexible receptacles, e.g. bags supported by rigid containers · CPC title

• B01F35/41

  Mounting or supporting stirrer shafts or stirrer units on receptacles · CPC title

• B01F27/11253

  the blades extending oblique to the stirrer axis · CPC title