Bicyclic compound and use thereof for medical purposes
US-11617733-B2 · Apr 4, 2023 · US
US12201603B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12201603-B2 |
| Application number | US-202318169716-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 15, 2023 |
| Priority date | Jul 28, 2009 |
| Publication date | Jan 21, 2025 |
| Grant date | Jan 21, 2025 |
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Since a compound represented by the general formula (I) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.
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The invention claimed is: 1. A pharmaceutical composition comprising the compound of formula (I): wherein the composition is an eye drop formulation.
Eye, e.g. artificial tears · CPC title
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
linked by a chain containing hetero atoms as chain links · CPC title
directly linked by a ring-member-to-ring-member bond · CPC title
condensed with carbocyclic rings or ring systems · CPC title
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