Excitonic quantum computing mediated by chromophore-embedded 1-, 2-, and 3-dimensional DNA scaffolds

Patent metadata

Field	Value
Publication number	US-12173027-B2
Application number	US-201816100052-A
Country	US
Kind code	B2
Filing date	Aug 9, 2018
Priority date	Aug 9, 2017
Publication date	Dec 24, 2024
Grant date	Dec 24, 2024

Abstract

Using nucleotide architectures to very closely and precisely placed chromophores that produce quantum coherent excitons, biexcitons, and triexcitons upon excitement to create excitonic quantum wires, switching, and gates that would then form the basis of quantum computation. Creating the various excitons and controlling the timing of the excitons would be performed using light of the corresponding wavelength and polarization to stimulate the corresponding chromophores.

First claim

What is claimed is:

1. A nucleotide brick molecular canvas used for quantum computing, comprising:
at least one nucleotide brick; and
at least two chromophores, wherein said at least two chromophores are bound to the at least one nucleotide brick, and wherein said at least two chromophores are nanospaced from each other;
wherein the at least two chromophores comprise at least two asymmetric molecules, each of the asymmetric molecules comprising a permanent electric dipole which changes sign when the each of the asymmetric molecules are excited from the ground state to the excited state.

2. The nucleotide brick molecular canvas of claim 1 , wherein the canvas comprises between 1 and about 5,000 bricks.

3. The nucleotide brick molecular canvas of claim 1 , wherein the at least one nucleotide brick comprises one or more of RNA, DNA, LNA, PNA, and/or UNA and is about 24 to about 42 nucleotides in length.

4. The nucleotide brick molecular canvas of claim 1 , wherein said at least one of the at least two chromophores is one or more of: 6-FAM, 6-FAM (Fluorescein), Fluorescein dT, Cy3, TAMRA, JOE, Cy5, MAX, TET, Cy5.5, ROX, TYE 563, Yakima Yellow, HEX, TEX 615, TYE 665, TYE 705, Alexa Fluor 488, 532, 546, 647, 660, 750, 5′ IRDye 700, 800, and 800CW, Rho101, 590, 633, 647N, Rhodamine Green-X, Rhodamine Red-X, and 5-TAMRA, WellRED D4, D3, and D2, 6-FAM, Fluorescein, Dy-530, -547, -547P1, -548, -549, -549P1, -550, -554, -555, -556, -560, -590, -591, -594, -605, -610, -615, -630, -631, -632, -633, -634, -635, -636, -647, -647P1, -648, -648P1, -649, -649P1, -650, -651, -652, -654, -675, -676, -677, -678, -679P1, -680, -681, -682, -700, -701, -703, -704, -705, 730, -731, -732, -734, -749, -749P1, -750, -751, -752, 754, -756, -757, -758, -780, -781, -782, -800, -831, -480XL, -481XL, -485XL, -510XL, -511XL, -520XL, -521XL, and/or -601XL.

5. The nucleotide brick molecular canvas of claim 1 , wherein, in addition to said at least two chromophores, the nucleotide brick molecular canvas further comprises at least one symmetric molecule.

6. The nucleotide brick molecular canvas of claim 1 , wherein said nucleotide brick molecular canvas further comprises one or more of one-, two-, and/or three-dimensional sections.

7. The nucleotide brick molecular canvas of claim 1 , wherein the at least two chromophores are covalently bound to the bricks.

8. The nucleotide brick molecular canvas of claim 1 , wherein at least one of the at least two chromophores is covalently bound to a linker nucleotide oligomer and wherein said linker nucleotide oligomer Watson-Crick pairs with a brick within the nucleotide brick molecular canvas.

9. The nucleotide brick molecular canvas of claim 1 , wherein said nucleotide brick molecular canvas further comprises exciton gates and/or exciton switches.

10. A complex quantum circuit for quantum computing, comprising:
at least two nucleotide brick molecular canvases of claim 1 , wherein a first nucleotide brick molecular canvas is aligned to a second nucleotide brick molecular canvas, and wherein an output chromophore of said first nucleotide brick molecular canvas is spaced close enough to an input chromophore of said second nucleotide brick molecular canvas such that the output chromophore can pass an exciton to the input chromophore.

11. The complex quantum circuit for quantum computing of claim 10 , wherein said at least two canvases each comprise between 1 and about 5,000 bricks.

12. The complex quantum circuit for quantum computing of claim 10 , wherein the bricks comprise one or more of RNA, DNA, LNA, PNA, and/or UNA and are about 24 to about 42 nucleotides in length.

13. The complex quantum circuit for quantum computing of claim 10 , wherein at least one of the at least two chromophores is one or more of: 6-FAM, 6-FAM (Fluorescein), Fluorescein dT, Cy3, TAMRA, JOE, Cy5, MAX, TET, Cy5.5, ROX, TYE 563, Yakima Yellow, HEX, TEX 615, TYE 665, TYE 705, Alexa Fluor 488, 532, 546, 647, 660, 750, 5′ IRDye 700, 800, and 800CW, Rho101, 590, 633, 647N, Rhodamine Green-X, Rhodamine Red-X, and 5-TAMRA, WellRED D4, D3, and D2, 6-FAM, Fluorescein, Dy-530, -547, -547P1, -548, -549, -549P1, -550, -554, -555, -556, -560, -590, -591, -594, -605, -610, -615, -630, -631, -632, -633, -634, -635, -636, -647, -647P1, -648, -648P1, -649, -649P1, -650, -651, -652, -654, -675, -676, -677, -678, -679P1, -680, -681, -682, -700, -701, -703, -704, -705, 730, -731, -732, -734, -749, -749P1, -750, -751, -752, 754, -756, -757, -758, -780, -781, -782, -800, -831, -480XL, -481XL, -485XL, -510XL, -511XL, -520XL, -521XL, and/or -601XL.

14. The complex quantum circuit for quantum computing of claim 10 , wherein at least one of the at least two chromophores is asymmetrical.

15. The complex quantum circuit for quantum computing of claim 10 , wherein said nucleotide brick molecular canvases further comprises one or more of one-, two-, and/or three-dimensional sections.

16. The complex quantum circuit for quantum computing of claim 10 , wherein at least one of the at least two chromophores is covalently bound to the bricks.

17. The complex quantum circuit for quantum computing of claim 10 , wherein at least one of the at least two chromophores is covalently bound to a linker nucleotide oligomer and wherein said linker nucleotide oligomer Watson-Crick pairs with a brick within the nucleotide brick molecular canvas.

18. The complex quantum circuit for quantum computing of claim 10 , wherein said nucleotide brick molecular canvases further comprises one or more of exciton wires, exciton gates, and/or exciton switches.

19. The complex quantum circuit for quantum computing of claim 10 , wherein:
the input chromophore is exposed to light, wherein said light comprises a wavelength and polarization within the absorbance range for said polarization of said input chromophore.

20. The complex quantum circuit for quantum computing of claim 19 , wherein said least two nucleotide brick molecular canvases comprise between 1 and about 5,000 bricks.

21. The complex quantum circuit for quantum computing of claim 19 , wherein the bricks comprise one or more of RNA, DNA, LNA, PNA, and/or UNA and are about 24 to about 42 nucleotides in length.

22. The complex quantum circuit for quantum computing of claim 19 , wherein at least one of the at least two chromophores is one or more of: 6-FAM, 6-FAM (Fluorescein), Fluorescein dT, Cy3, TAMRA, JOE, Cy5, MAX, TET, Cy5.5, ROX, TYE 563, Yakima Yellow, HEX, TEX 615, TYE 665, TYE 705, Alexa Fluor 488, 532, 546, 647, 660, 750, 5′ IRDye 700, 800, and 800CW, Rho101, 590, 633, 647N, Rhodamine Green-X, Rhodamine Red-X, and 5-TAMRA, WellRED D4, D3, and D2, 6-FAM, Fluorescein, Dy-530, -547, -547P1, -548, -549, -549P1, -550, -554, -555, -556, -560, -590, -591, -594, -605, -610, -615, -630, -631, -632, -633, -634, -635, -636, -647, -647P1, -648, -648P1, -649, -649P1, -650, -651, -652, -654, -675, -676, -677, -678, -679P1, -680, -681, -682, -700, -701, -703, -704, -705, 730, -731, -732, -734, -749, -749P1, -750, -751, -752, 754, -756, -757, -758, -780, -781, -782, -800, -831, -480XL, -481XL, -485XL, -510XL, -511XL, -520XL, -521XL, and/or -601XL.

23. The complex quantum circuit for quantum computing of claim 19 , wherein at least one of the at least two chromophores is asymmetrical.

24. The complex quantum circuit for quantum computing of claim 19 , wherein said nucleotide brick molecular canvases further comprises one or more of one-, two-, and/or three-dimensional sections.

Assignees

• Univ Boise State

Inventors

• Yurke Bernard

Classifications

• G06N10/00

  Quantum computing, i.e. information processing based on quantum-mechanical phenomena · CPC title

• G06N10/20

  Models of quantum computing, e.g. quantum circuits or universal quantum computers · CPC title

• G06N3/123

  DNA computing · CPC title

• C09B23/083

  five >CH- groups · CPC title

• C07H21/02

  with ribosyl as saccharide radical · CPC title