Fluid delivery device having an insertable prefilled cartridge

Patent metadata

Field	Value
Publication number	US-12168114-B2
Application number	US-202318296162-A
Country	US
Kind code	B2
Filing date	Apr 5, 2023
Priority date	May 31, 2013
Publication date	Dec 17, 2024
Grant date	Dec 17, 2024

Abstract

A fluid delivery device includes a housing having a bottom surface configured to be coupled to the skin surface. The fluid delivery device includes a cartridge prefilled with a fluid and configured to be inserted into the housing. The cartridge has a septum configured to be generally perpendicular to the bottom surface when the cartridge is inserted in the housing. The fluid delivery device includes a needle assembly that has a needle that includes a fluid coupling end and a delivery end. The fluid coupling end of the needle is fluidly disengaged from the cartridge in an initial position. The delivery end of the needle extends past the plane of the bottom surface and the fluid coupling end of the needle extends through the septum in a deployed position.

First claim

We claim:

1. A fluid delivery device comprising:
a housing having a bottom surface configured to be coupled to a skin surface, the housing including a hydraulic fluid drive containing a hydraulic fluid, the hydraulic fluid drive including a first hydraulic chamber and a second hydraulic chamber, the first hydraulic chamber being fluidly coupled to the second hydraulic chamber by a flow restrictor;
a cartridge prefilled with a fluid and configured to be inserted into the housing, the cartridge having a septum; and
a needle assembly having a needle including a fluid coupling end and a delivery end, the fluid coupling end of the needle being fluidly disengaged from the cartridge in an initial position, the delivery end of the needle extending past a plane co-planar with the bottom surface in a deployed position and the fluid coupling end of the needle extending through the septum in the deployed position,
wherein the hydraulic fluid drive includes a port configured to couple with the cartridge, the port having a seal that is closed prior to inserting the cartridge into the housing and released when the cartridge is coupled with the port, the cartridge including a piston moveable by the hydraulic fluid when the needle is in the deployed position,
wherein the seal includes a slideable valve having one or more fluid passages configured to fluidly couple the hydraulic fluid drive and the piston.

2. The delivery device of claim 1 , wherein the one or more fluid passages are filled with a fluid prior to the cartridge being inserted into the housing.

3. The fluid delivery device of claim 1 , wherein the septum is generally perpendicular to the bottom surface when the cartridge is inserted in the housing.

4. A fluid delivery device comprising:
a housing having a bottom surface configured to be coupled to a skin surface, the housing including a hydraulic fluid drive containing a hydraulic fluid, the hydraulic fluid drive including a first hydraulic chamber and a second hydraulic chamber, the first hydraulic chamber being fluidly coupled to the second hydraulic chamber by a flow restrictor;
a cartridge prefilled with a fluid and configured to be inserted into the housing, the cartridge having a septum; and
a needle assembly having a needle including a fluid coupling end and a delivery end, the fluid coupling end of the needle being fluidly disengaged from the cartridge in an initial position, the delivery end of the needle extending past a plane co-planar with the bottom surface in a deployed position and the fluid coupling end of the needle extending through the septum in the deployed position,
wherein the hydraulic fluid drive includes a port configured to couple with the cartridge, the port having a seal that is closed prior to inserting the cartridge into the housing and released when the cartridge is coupled with the port, the cartridge including a piston moveable by the hydraulic fluid when the needle is in the deployed position,
wherein the hydraulic fluid drive is fluidly coupled to an accumulator configured to allow thermal expansion and contraction of the hydraulic fluid.

5. The fluid delivery device of claim 4 , wherein the accumulator is fluidly coupled to the hydraulic fluid drive when the seal is closed and fluidly disengaged from the hydraulic fluid drive when the seal is released.

6. A fluid delivery device comprising:
a housing having a bottom surface configured to be coupled to a skin surface, the housing including a hydraulic fluid drive containing a hydraulic fluid, the hydraulic fluid drive including a first hydraulic chamber and a second hydraulic chamber, the first hydraulic chamber being fluidly coupled to the second hydraulic chamber by a flow restrictor;
a cartridge prefilled with a fluid and configured to be inserted into the housing, the cartridge having a septum; and
a needle assembly having a needle including a fluid coupling end and a delivery end, the fluid coupling end of the needle being fluidly disengaged from the cartridge in an initial position, the delivery end of the needle extending past a plane co-planar with the bottom surface in a deployed position and the fluid coupling end of the needle extending through the septum in the deployed position,
wherein the hydraulic fluid drive includes a port configured to couple with the cartridge, the port having a seal that is closed prior to inserting the cartridge into the housing and released when the cartridge is coupled with the port, the cartridge including a piston moveable by the hydraulic fluid when the needle is in the deployed position,
wherein the port includes a ball joint receiver that is at an acute angle relative to the bottom surface of the housing until the cartridge is retained in place relative to the housing.

7. A fluid delivery device comprising:
a housing having a bottom surface configured to be coupled to a skin surface, the housing including a hydraulic fluid drive containing a hydraulic fluid, the hydraulic fluid drive including a first hydraulic chamber and a second hydraulic chamber, the first hydraulic chamber being fluidly coupled to the second hydraulic chamber by a flow restrictor;
a cartridge prefilled with a fluid and configured to be inserted into the housing, the cartridge having a septum; and
a needle assembly having a needle including a fluid coupling end and a delivery end, the fluid coupling end of the needle being fluidly disengaged from the cartridge in an initial position, the delivery end of the needle extending past a plane co-planar with the bottom surface in a deployed position and the fluid coupling end of the needle extending through the septum in the deployed position,
wherein the hydraulic fluid drive includes a port configured to couple with the cartridge, the port having a seal that is closed prior to inserting the cartridge into the housing and released when the cartridge is coupled with the port, the cartridge including a piston moveable by the hydraulic fluid when the needle is in the deployed position,
wherein the piston includes a spike configured to pierce the seal when the cartridge is coupled with the port.

Assignees

• Mannkind Corp

Inventors

• Gregory Christopher C
• Johnson Matthew P
• Standley Robert L

Classifications

• A61M5/14526 Primary

  the piston being actuated by fluid pressure · CPC title

• A61M5/1407

  Infusion of two or more substances · CPC title

• A61M5/288

  by piercing without internal pressure increase (A61M5/283 takes precedence) · CPC title

• A61M2005/1585

  Needle inserters · CPC title

• A61M5/162

  Needle sets, i.e. connections by puncture between reservoir and tube {; Connections between reservoir and tube (in jet-action syringes A61M5/30; connectors for tubes having sealed ends and a needle for piercing them A61M39/14)} · CPC title