Balloon expandable stent with lengthened commissure posts for transcatheter implantation of a cardiac valve prosthesis

Patent metadata

Field	Value
Publication number	US-12011349-B2
Application number	US-202117186485-A
Country	US
Kind code	B2
Filing date	Feb 26, 2021
Priority date	Mar 4, 2020
Publication date	Jun 18, 2024
Grant date	Jun 18, 2024

Abstract

A transcatheter valve prosthesis includes a stent and a prosthetic valve. The stent includes an inflow portion, an outflow portion, and a transition portion extending between the inflow portion and the outflow portion. The transition portion includes a plurality of axial frame members, and three of the plurality of the axial frame members are commissure posts. At least two of the plurality of the axial frame members are commissure posts having a first end connected to a crown of the inflow portion and an unattached second end disposed within the outflow portion such that a pair of struts of the outflow portion intersect each commissure post at a mid-portion thereof. The prosthetic valve is configured to substantially block blood flow in one direction to regulate blood flow through a central lumen of the stent.

First claim

What is claimed is:

1. A transcatheter valve prosthesis comprising:
a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, the stent including
an inflow portion formed proximate to an inflow end of the stent, the inflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, a plurality of side openings being defined by the plurality of crowns and the plurality of struts, wherein endmost inflow side openings and endmost inflow crowns are formed at the inflow end of the stent,
an outflow portion formed proximate to an outflow end of the stent, the outflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, wherein endmost outflow crowns are formed at the outflow end of the stent, and wherein a total of the endmost inflow crowns are greater than a total of the endmost outflow crowns,
a transition portion extending between the inflow portion and the outflow portion, the transition portion including a plurality of axial frame members, wherein at least two axial frame members of the plurality of axial frame members are commissure posts having a first end connected to a single crown at an outflow end of the inflow portion and an unattached second end disposed within the outflow portion such that a pair of struts of the outflow portion intersect each commissure post at a mid-portion thereof, and

a prosthetic valve disposed within and secured to at least the transition portion of the stent, the prosthetic valve being configured to substantially block blood flow in one direction to regulate blood flow through a central lumen of the stent.

2. The transcatheter valve prosthesis of claim 1 , wherein the prosthetic valve includes three leaflets, and wherein the transition portion includes a total of six axial frame members, with three of the six axial frame members being commissure posts, each axial frame member disposed approximately halfway between a pair of adjacent endmost outflow crowns, and wherein the commissure posts are aligned with and attached to a respective commissure of the three leaflets of the prosthetic valve.

3. The transcatheter valve prosthesis of claim 1 , wherein the transition portion includes a total of six axial frame members and a total of six endmost outflow side openings are formed at the outflow end of the stent, each endmost outflow side opening being defined by two struts of the outflow portion, four struts of the inflow portion, and two axial frame members of the transition portion.

4. The transcatheter valve prosthesis of claim 1 , wherein the unattached second end of each commissure post does not extend beyond the endmost outflow crowns of the outflow portion.

5. The transcatheter valve prosthesis of claim 1 , wherein each commissure post extends substantially parallel to a central longitudinal axis of the stent.

6. The transcatheter valve prosthesis of claim 1 , wherein a directional marker is formed on at least one commissure post, the directional marker being an axially non-symmetrical element or opening.

7. The transcatheter valve prosthesis of claim 1 , wherein the total of the endmost inflow crowns is twice the total of the endmost outflow crowns.

8. The transcatheter valve prosthesis of claim 1 , further comprising:
a plurality of radiopaque inflow markers disposed on the inflow portion of the stent, wherein the radiopaque inflow markers are circumferentially aligned with each other around a circumference of the stent; and
a first outflow marker and a second outflow marker, wherein the first outflow marker is disposed on a first commissure post of the commissure posts of the stent and the second outflow marker is positioned on a first axial frame member of the axial frame members of the stent, the first axial frame member being directly adjacent to the first commissure post.

9. The transcatheter valve prosthesis of claim 8 , wherein one of the first outflow marker and the second outflow marker is positioned closer to an outflow end of the stent relative to the other of the first outflow marker and the second outflow marker.

10. The transcatheter valve prosthesis of claim 8 , wherein only the first commissure post of the commissure posts includes a marker disposed thereon and only the first axial frame member of the axial frame members includes a marker disposed thereon.

11. The transcatheter valve prosthesis of claim 8 , wherein the plurality of radiopaque inflow markers comprises six plurality of radiopaque inflow markers positioned at distinct locations around the circumference of the stent.

12. A transcatheter valve prosthesis comprising:
a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, the stent including
an inflow portion including at least three rows of struts and crowns formed between adjacent pairs of said struts,
an outflow portion including a single row of struts and crowns formed between adjacent pair of said struts, and
a plurality of axial frame members, wherein the at least three rows of the inflow portion are formed between an inflow end of the axial frame members and an inflow end of the stent, and wherein the outflow portion is coupled to an outflow end of the axial frame members, wherein exactly two struts of the plurality of struts of the outflow portion are disposed between adjacent axial frame members, at least two axial frame members of the plurality of axial frame members being commissure posts having a first end connected to a single crown at an outflow end of the inflow portion and an unattached second end disposed within the outflow portion such that a pair of struts of the outflow portion intersect each commissure post at a mid-portion thereof, wherein a directional marker is formed on at least one commissure post, the directional marker being an axially non-symmetrical element or opening.

13. The transcatheter valve prosthesis of claim 12 ,
wherein the plurality of axial frame members includes exactly six axial frame members,
wherein three of the six axial frame members are commissure posts and three of the six axial frame members are axial struts, and
wherein each of the axial struts is disposed between adjacent commissure posts.

14. The transcatheter valve prosthesis of claim 13 , wherein one of the at least three rows of struts and crowns of the inflow portion includes crowns coupled to inflow end of the axial frame member, wherein the one row includes at least four struts between adjacent axial frame members.

15. The transcatheter valve prosthesis of claim 12 , wherein the plurality of axial frame members includes a plurality of axial struts and a plurality of commissure posts, wherein there are the same number of axial struts and commissure posts, wherein each of the axial struts is disposed between adjacent commissure posts.

16. The transcatheter valve prosthesis of claim 12 , wherein the unattached second end of each commissure post does not extend beyond endmost outflow crowns of the outflow portion.

17. A transcatheter valve prosthesis comprising:
a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, the stent including
an inflow portion including at least three rows of struts and crowns formed between adjacent pairs of said struts,
an outflow portion including a single row of st

Assignees

• Medtronic Inc

Inventors

• Peterson Justin
• Kari Stuart
• Javani Shahnaz
• Farrar Genevieve
• Askari Syed
• Kibria Alkindi
• Olney Karl
• Garde Kshitija
• Goshgarian Justin
• Tien Tracey
• Korngold Ethan
• Casley Mark

Classifications

• A61F2/9522

  Means for mounting a stent or stent-graft onto or into a placement instrument · CPC title

• A61F2/2433

  using balloon catheter · CPC title

• A61F2250/001

  for adjusting a diameter · CPC title

• A61F2250/0036

  differing in thickness · CPC title

• A61F2250/0098

  radio-opaque, e.g. radio-opaque markers · CPC title