Radiation treatment planning for delivering high dose rates to spots in a target

Patent metadata

Field	Value
Publication number	US-11986672-B2
Application number	US-202217681612-A
Country	US
Kind code	B2
Filing date	Feb 25, 2022
Priority date	Oct 3, 2019
Publication date	May 21, 2024
Grant date	May 21, 2024

Abstract

Information that describes a target inside a patient to be treated with radiation is accessed from computer system memory. An arrangement of spots inside the target is determined. Each the spots corresponds to a location inside the target where a respective beam of radiation is to be directed during radiation treatment of the patient. A dose rate for each of the beams is determined. The dose rate for each beam is a dose delivered in less than one second to a spot corresponding to that beam. For example, each beam can deliver at least four grays (GY) in less than one second, and may deliver as much as 20 Gy to 50 Gy or 100 Gy or more in less than one second. A radiation treatment plan, that includes the arrangement of the spots and the dose rate for each of the beams, is stored in computer system memory.

First claim

What is claimed is:

1. A computer system, comprising:
a processor; and
memory coupled to the processor and comprising instructions that, when executed, cause the processor to execute operations to generate a radiation treatment plan, the operations comprising:
accessing, from the memory, a minimum prescribed dose rate to be delivered by beams into spots in a target in a patient;
determining a number of the spots and an arrangement of the spots in the target; and
determining a beam energy for each beam of the beams, wherein the beam energy for said each beam of the beams is determined such that each spot of the spots receives the minimum prescribed dose rate.

2. The computer system of claim 1 , wherein the minimum prescribed dose rate is four Grays per second.

3. The computer system of claim 1 , wherein the minimum prescribed dose rate is 20 Grays per second.

4. The computer system of claim 1 , wherein a ratio of dose rate inside a spot to a dose rate outside a spot is at least 1.5.

5. The computer system of claim 1 , wherein the beams comprise a type of beam selected from the group consisting of: proton; electron; photon; atom nuclei; and ion.

6. The computer system of claim 1 , wherein the beam energy for said each beam of the beams is determined using parameters comprising a number of irradiations for a respective spot corresponding to said each beam, a duration of each irradiation of the irradiations for the respective spot, and a dose deposited in each irradiation of the irradiations for the respective spot.

7. The computer system of claim 6 , wherein the parameters further comprise: a period of time during which the irradiations are applied, and an interval of time between each period of irradiations.

8. The computer system of claim 1 , wherein the operations further comprise determining a dose rate for said each beam of the beams.

9. The computer system of claim 8 , wherein the dose rate for said each beam is a dose delivered in less than one second to a respective spot corresponding to said each beam.

10. The computer system of claim 1 , wherein the operations further comprise storing, to the memory, the radiation treatment plan, wherein the radiation treatment plan comprises the arrangement of the spots and the beam energy for said each beam of the beams.

11. A computer-implemented method of radiation treatment planning, the method comprising:
accessing, from memory of a computer system, a minimum prescribed dose rate to be delivered by beams into spots in a target in a patient;
determining a number of the spots and an arrangement of the spots in the target; and
determining a beam energy for each beam of the beams, wherein the beam energy for said each beam of the beams is determined such that each spot of the spots receives the minimum prescribed dose rate.

12. The method of claim 11 , wherein the minimum prescribed dose rate is four Grays per second.

13. The method of claim 11 , wherein the minimum prescribed dose rate is 20 Grays per second.

14. The method of claim 11 , wherein a ratio of dose rate inside a spot to a dose rate outside a spot is at least 1.5.

15. The method of claim 11 , wherein the beams comprise a type of beam selected from the group consisting of: proton; electron; photon; atom nuclei; and ion.

16. The method of claim 11 , wherein the beam energy for said each beam of the beams is determined using parameters comprising a number of irradiations for a respective spot corresponding to said each beam, a duration of each irradiation of the irradiations for the respective spot, and a dose deposited in each irradiation of the irradiations for the respective spot.

17. The method of claim 16 , wherein the parameters further comprise: a period of time during which the irradiations are applied, and an interval of time between each period of irradiations.

18. The method of claim 11 , further comprising determining a dose rate for said each beam of the beams.

19. The method of claim 18 , wherein the dose rate for said each beam is a dose delivered in less than one second to a respective spot corresponding to said each beam.

20. The method of claim 11 , further comprising storing, to memory of a computer system, a radiation treatment plan comprising the arrangement of the spots and the beam energy for said each beam of the beams.

Assignees

• Varian Med Sys Inc
• Siemens Healthineers Int Ag

Inventors

• Abel Eric
• Katsis Alexander

Classifications

• A61N5/1038 Primary

  taking into account previously administered plans applied to the same patient, i.e. adaptive radiotherapy · CPC title

• A61N5/103 Primary

  Treatment planning systems · CPC title

• A61N2005/1087

  Ions; Protons · CPC title

• A61N2005/1089

  Electrons · CPC title

• A61N2005/109

  Neutrons · CPC title