Upstream direct x-ray detection

Patent metadata

Field	Value
Publication number	US-9517358-B2
Application number	US-201113996616-A
Country	US
Kind code	B2
Filing date	Dec 21, 2011
Priority date	Dec 22, 2010
Publication date	Dec 13, 2016
Grant date	Dec 13, 2016

Abstract

A radiation beam, for example a therapeutic radiation beam such as an IMRT or VMAT X-ray beam is monitored using a Monolithic Active Pixel Sensor (MAPS) detector. Photons of the radiation beam can interact with the MAPS detector, and the radiation beam configuration can be estimated from the determined positions of the interactions. The detector is made sufficiently thin that it interacts only very weakly with the X-ray photons. For example, less than 1 in 10 3 of the X-ray photons might interact with the detector. Hence, the disturbance to the X-ray beam is negligible.

First claim

The invention claimed is:

1. A method of monitoring an X-ray radiation beam for treatment of a patient, the method comprising:
placing in the radiation beam a monolithic active pixel sensor (MAPS) detector between the patient and an x-ray source;
exposing the MAPS detector to the radiation beam, such that photons of the radiation beam can interact with the MAPS detector wherein the MAPS detector has a thickness configured such that it interacts with a maximum of 1 in 10 3 photons of the X-ray beam incident on the detector;
determining a position of each identified interaction; and
estimating a configuration of the radiation beam delivered to the patient from the determined positions of the interactions.

2. A method as claimed in claim 1 , comprising:
exposing the MAPS detector to the radiation beam for a plurality of successive frames; and further comprising:
in each frame, identifying each interaction between a photon of the radiation beam and the MAPS detector;
determining a position of each identified interaction; and
estimating the radiation beam configuration from the determined positions of the interactions over the plurality of frames.

3. A method as claimed in claim 1 , further comprising:
distinguishing between interactions between incident photons of the radiation beam and the MAPS detector, and interactions between incident electrons and the MAPS detector.

4. A method as claimed in claim 3 , comprising:
identifying each interaction between a photon of the radiation beam and the MAPS detector, based on a shape of a cluster of detector pixels excited by the interaction.

5. A method as claimed in claim 4 , comprising:
identifying an interaction between a photon of the radiation beam and the MAPS detector, in the event that a cluster of detector pixels excited by the interaction comprises a tail extending linearly over at least three pixels.

6. A radiation detection treatment system, comprising: a radiation source for generating a beam of X-ray radiation; a first surface on which a patient can be positioned and a monolithic active pixel sensor (MAPS) detector, for exposure to a beam of X-ray radiation and configured so as to be located, in use, in the beam of X-ray radiation between the surface and the radiation source, wherein the MAPS detector has a thickness configured such that it interacts with a maximum of 1 in 10 3 photons of the X-ray beam incident on the detector; and a processing system, wherein the processing system is configured to identify interactions between photons of the radiation beam and the MAPS detector, to determine a position of each identified interaction, and to estimate the radiation beam configuration delivered to the patient from the determined positions of the interactions.

7. A radiation treatment system as claimed in claim 6 , wherein the processing system is configured to distinguish between interactions between incident photons of the radiation beam and the MAPS detector, and interactions between incident electrons and the MAPS detector.

8. A radiation treatment system as claimed in claim 7 , wherein the processing system is configured to identify each interaction between a photon of the radiation beam and the MAPS detector, based on a shape of a cluster of detector pixels excited by the interaction.

9. A radiation treatment system as claimed in claim 8 , wherein the processing system is configured to identify an interaction between a photon of the radiation beam and the MAPS detector, in the event that a cluster of detector pixels excited by the interaction comprises a tail extending linearly over at least three pixels.

10. A method for monitoring and/or signalling errors of a radiation therapy apparatus during delivery of X-ray radiation treatment to a patient, said radiation therapy apparatus being configured for Intensity Modulated Radiation Therapy, the method comprising the steps of: providing a monolithic active pixel sensor (MAPS) between a radiation source and said patient, capable of providing a measured detector response of radiation treatment, wherein the MAPS detector has a thickness configured such that it interacts with a maximum of 1 in 10 3 photons of the X-ray beam incident on the detector; determining a predicted MAPS detector response for each successive time of the radiation treatment; measuring a MAPS detector response for each successive time of the radiation treatment; performing a comparison between measured MAPS detector response and the corresponding predicted MAPS detector response; and signalling in a short reaction time an error when the comparison results in a difference which exceeds a given threshold.

Assignees

• Velthuis Jaap
• Hugtenburg Peter Richard
• Hall Catherine
• Page Ryan
• Stevens Paul
• Univ Bristol

Inventors

• Velthuis Jaap
• Hugtenburg Peter Richard
• Hall Catherine
• Page Ryan
• Stevens Paul

Classifications

• A61N5/1047

  with movement of the radiation head during application of radiation, e.g. for intensity modulated arc therapy or IMAT · CPC title

• A61N5/1075

  for testing, calibrating, or quality assurance of the radiation treatment apparatus · CPC title

• G01T1/24

  with semiconductor detectors · CPC title

• A61N5/1071 Primary

  for verifying the dose delivered by the treatment plan · CPC title

• A61N5/1065 Primary

  Beam adjustment · CPC title