Multi-stroke delivery pumping mechanism for a drug delivery device for high pressure injections
US-10258749-B2 · Apr 16, 2019 · US
US11980746B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11980746-B2 |
| Application number | US-201916382383-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 12, 2019 |
| Priority date | Apr 19, 2018 |
| Publication date | May 14, 2024 |
| Grant date | May 14, 2024 |
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A syringe is provided. The syringe includes a syringe barrel including an open proximal end, a closed distal end, and a sidewall extending therebetween. The syringe also includes: a plunger having an annular sidewall configured to seal against an interior surface of the sidewall of the syringe barrel, the plunger being configured to move through the syringe barrel in proximal and distal directions; a pump in fluid communication with an interior volume of the syringe barrel, the pump being configured to draw fluid from the syringe barrel; and a nozzle including a lumen in fluid communication with the pump and configured to receive fluid drawn from the syringe barrel by the pump and to expel the fluid through a distal end of the lumen. The pump can be a valve-less piston pump.
Opening claim text (preview).
The invention claimed is: 1. A syringe comprising: a syringe barrel comprising an open proximal end, a closed distal end, and a sidewall extending therebetween; a plunger having an annular sidewall configured to seal against an interior surface of the sidewall of the syringe barrel, the plunger being configured to move through the syringe barrel in proximal and distal directions; a rotary valve-less piston pump directly connected to and in fluid communication with an interior volume of the syringe barrel configured to draw fluid from the syringe barrel by rotation of a piston, the rotary valve-less piston pump comprising an annular body having an open proximal end and a closed distal end, which define a cavity, the cavity being in fluid communication with the interior volume of the syringe barrel and a lumen of a nozzle, wherein the annular body comprises at least one annular seal extending from an interior sidewall thereof, the seal being configured to prevent fluid from leaking from the open proximal end of the annular body; and the nozzle comprising the lumen aligned and directly connected with the nozzle and in fluid communication with the rotary valve-less piston pump configured to receive fluid drawn from the syringe barrel by the pump and to expel the fluid through a distal end of the lumen, such that the fluid flows from the syringe barrel to the rotary valve-less piston pump and then to a distal end of the nozzle, the rotary valve-less piston pump connected between the syringe barrel and the nozzle, a drive unit connected to the pump for actuating the pump to draw fluid from the interior volume of the syringe barrel, the drive unit comprising a motor, a rotating shaft, a track, a linear actuator, and a cam, wherein rotation of the cam by the shaft causes the piston to travel along the track, wherein the piston is slidably rotatably inserted in the cavity, wherein, when the piston is in a partially retracted position during use, fluid flow between the lumen of the nozzle and the interior volume of the syringe barrel through the cavity of the pump is permitted, such that the fluid comes in contact with a bottom surface of the piston, and wherein movement of the plunger in the distal direction allows the expel of the fluid through the distal end of the lumen and the nozzle, the lumen, and the direction of the movement of the plunger are coaxial. 2. The syringe of claim 1 , wherein, when the piston is in a partially retracted position, fluid flow through the open proximal end of the annular body is prevented. 3. The syringe of claim 2 , wherein movement of the piston in an axial direction into the cavity from the partially retracted position causes the piston to seal at least one of the lumen of the nozzle or the interior volume of the syringe barrel, such that fluid communication between the cavity and the nozzle and/or the syringe barrel is prevented. 4. The syringe of claim 1 , wherein, during a piston stroke, the piston rotates 360 degrees and moves axially through the cavity between a seated position, a suction position, and back to the seated position. 5. The syringe of claim 4 , wherein in the suction position, fluid is drawn from the interior of the syringe barrel into the cavity and, wherein, in the seated position, fluid is expelled from the cavity through the lumen of the nozzle. 6. The syringe of claim 1 , wherein the nozzle further comprises a male luer connector configured to connect to a female luer connector of another fluid delivery device to establish fluid communication between the syringe and the fluid delivery device. 7. The syringe of claim 1 , wherein the nozzle further comprises a threaded connector comprising an annular body having threads on an interior surface thereof. 8. The syringe of claim 1 , wherein the pump is integrally molded to the syringe barrel. 9. The syringe of claim 1 , wherein the pump is removably connected to the syringe barrel. 10. A syringe assembly for delivery of a fluid, comprising: a syringe comprising a syringe barrel comprising an open proximal end, a closed distal end, and a sidewall extending therebetween; a plunger disposed in the syringe barrel having an annular sidewall configured to seal an interior surface of the sidewall of the syringe barrel and configured to move through the syringe barrel in proximal and distal directions; and a nozzle extending from the distal end of the syringe barrel comprising a lumen in fluid communication with an interior volume of the syringe barrel; and a pump assembly removably and directly connected to the nozzle of the syringe barrel in fluid communication with the interior volume of the syringe barrel, the pump assembly comprising a rotary piston pump configured to draw fluid from the interior volume of the syringe barrel through an inflow port of the pump assembly and to expel the received fluid from an outflow port thereof by rotational movement of a piston, a drive unit connected to the pump for actuating the pump to draw fluid from the interior volume of the syringe barrel, the drive unit comprising a motor, a rotating shaft, a track, a linear actuator, and a cam, wherein rotation of the cam by the shaft causes the piston to travel along the track, wherein the rotary piston pump comprises a rotary valve-less piston pump comprising an annular body having an open proximal end and a closed distal end, which define a cavity, wherein the piston is slidably inserted into the cavity, wherein the fluid is drawn from the interior volume of the syringe barrel into the cavity through the inflow port and is expelled from the cavity through the outflow port into the nozzle, such that the fluid comes into contact with a bottom surface of the rotary piston pump in the cavity, after which the fluid is expelled through the outflow port, wherein to permit fluid flow between the lumen of the nozzle and the interior volume of the syringe barrel through the cavity of the pump during use to allow for fluid to be drawn with the plunger, the piston is in a partially retracted position such that the fluid comes in contact with a bottom surface of the piston, and wherein movement of the plunger in the distal direction allows the expel of the fluid through the distal end of the lumen and the inflow port, the outflow port, and the direction of the movement of the plunger are axially aligned. 11. The assembly of claim 10 , wherein, when the piston is in a partially retracted position, fluid flow through the open proximal end of the annular body is prevented. 12. The assembly of claim 11 , wherein movement of the piston in an axial direction from the partially retracted position into the cavity causes the piston to seal at least one of the inflow port or the outflow port, such that fluid communication between the cavity and the inflow port and/or the outflow port is prevented. 13. The assembly of claim 10 , wherein, during a piston stroke, the piston rotates 360 degrees and moves axially through the cavity between a seated position, a suction position, and back to the seated position. 14. A fluid delivery system, comprising: a syringe comprising: a syringe barrel comprising an open proximal end, a closed distal end, and a sidewall extending therebetween; a plunger comprising an annular sidewall configured to seal against an interior surface of the sidewall of the syringe barrel and configured to move through the syringe barrel in proximal and distal directions; a rotary valve-less piston pump directly connected to and in fluid communication with an interior volume of the syringe barrel configured to draw fluid from the syringe barrel by rotational movement of a pi
Piston or piston-rod constructions, e.g. connection of piston with piston-rod (A61M5/5066 takes precedence) · CPC title
Syringe barrels (A61M5/3205 and A61M5/50 take precedence) · CPC title
by means of rotational movements, e.g. screw-thread mechanisms · CPC title
Dosing mechanisms, i.e. setting a dose (administrating mechanisms A61M5/31565) · CPC title
Constructional features thereof, e.g. to improve manipulation or functioning · CPC title
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