Multi-stroke delivery pumping mechanism for a drug delivery device for high pressure injections

Patent metadata

Field	Value
Publication number	US-10258749-B2
Application number	US-201514962508-A
Country	US
Kind code	B2
Filing date	Dec 8, 2015
Priority date	Dec 9, 2008
Publication date	Apr 16, 2019
Grant date	Apr 16, 2019

Abstract

A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.

First claim

The invention claimed is:

1. A dual-chambered drug delivery device, comprising:
a cartridge having a first chamber for storing a medicament;
a second chamber in fluid communication with said first chamber;
a dose setting member for setting a medicament dose to be injected at an injection site;
a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site;
a ratchet linearly movable between a first ratchet position and a second ratchet position by rotation of said dose setting member, said second ratchet position corresponding to the medicament dose being set; and
a rack movable by said ratchet when said ratchet is moved from said second ratchet position to said first ratchet position.

2. The dual-chambered drug delivery device according to claim 1 , wherein
upward movement of the dose setting member moves said ratchet upwardly from said first ratchet position to said second ratchet position.

3. The dual-chambered drug delivery device according to claim 1 , wherein
said rack has a movable rack member and a carriage, said movable rack member having a first rack position and a second rack position, said movable rack member moving said carriage when said movable rack member is moving toward said second rack position.

4. The dual-chambered drug delivery device according to claim 3 , wherein
said movable rack member moves up a ramp to move from said first rack position to said second rack position.

5. The dual-chambered drug delivery device according to claim 1 , wherein
said rack is connected to a cam wheel, such that movement of said rack rotates said cam wheel.

6. The dual-chambered drug delivery device according to claim 5 , wherein said cam wheel is connected to a piston such that rotation of said cam wheel reciprocatingly moves said piston, an upward stroke of said piston draws a portion of the medicament dose into said second chamber from said first chamber and a downward stroke of said piston expels the portion of the medicament dose.

7. A dual-chambered drug delivery device, comprising:
a cartridge having a first chamber for storing a medicament;
a second chamber in fluid communication with said first chamber;
a dose setting member for setting a medicament dose to be injected at an injection site;
a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site;
a ratchet movable between a first ratchet position and a second ratchet position by rotation of said dose setting member, said second ratchet position corresponding to the medicament dose being set; and
a rack movable by said ratchet when said ratchet is moved from said second ratchet position to said first ratchet position; wherein
in said second ratchet position, said ratchet is accessible outside a remaining portion of said dual-chambered drug delivery device.

8. A dual-chambered drug delivery device, comprising:
a cartridge having a first chamber for storing a medicament;
a second chamber in fluid communication with said first chamber;
a dose setting member for setting a medicament dose to be injected at an injection site;
a needle communicating with said second chamber for sequentially infecting portions of the medicament dose into the injection site;
a ratchet movable between a first ratchet position and a second ratchet position by rotation of said dose setting member, said second ratchet position corresponding to the medicament dose being set; and
a rack movable by said ratchet when said ratchet is moved from said second ratchet position to said first ratchet position; wherein
said rack has a movable rack member and a carriage, said movable rack member having a first rack position and a second rack position, said movable rack member moving said carriage when said movable rack member is moving toward said second rack position; and
when said carriage engages teeth connected to said ratchet, further medicament doses are prevented from being set.

9. A dual-chambered drug delivery device, comprising:
a cartridge having a first chamber for storing a medicament;
a second chamber in fluid communication with said first chamber;
a dose setting member for setting a medicament dose to be injected at an injection site;
a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site;
a ratchet movable between a first ratchet position and a second ratchet position by rotation of said dose setting member, said second ratchet position corresponding to the medicament dose being set; and
a rack movable by said ratchet when said ratchet is moved from said second ratchet position to said first ratchet position; wherein
said rack has a movable rack member and a carriage, said movable rack member having a first rack position and a second rack position, said movable rack member moving said carriage when said movable rack member is moving toward said second rack position; and
said cartridge is pressurized by a compression spring engaging a stopper disposed in said cartridge.

10. The dual-chambered drug delivery device according to claim 9 , wherein
a force from said compression spring moves said cartridge to pierce a septum of the cartridge.

Assignees

• Becton Dickinson Co

Inventors

• Schoonmaker Ryan
• Bruehwiler Michel
• Spool Ira
• Rosen Melissa

Classifications

• A61M5/286

  upon internal pressure increase, e.g. pierced or burst (A61M5/283 takes precedence) · CPC title

• A61M5/204

  connected to external reservoirs for multiple refilling · CPC title

• A61M5/31553

  without axial movement of dose setting member · CPC title

• A61M5/3146

  Priming, e.g. purging, reducing backlash or clearance · CPC title

• A61M5/14216

  Reciprocating piston type · CPC title