Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation including mixing and heating therefore

Patent metadata

Field	Value
Publication number	US-11939251-B2
Application number	US-202017061068-A
Country	US
Kind code	B2
Filing date	Oct 1, 2020
Priority date	May 6, 2016
Publication date	Mar 26, 2024
Grant date	Mar 26, 2024

Abstract

A peritoneal dialysis system includes a cycler including a pump actuator, a heater and a heating pan operable with the heater, and a disposable set operable with the cycler. The heating pan includes a sidewall forming a slot. The disposable set includes a pumping cassette and a heater/mixing container. The pumping cassette includes a pump chamber configured to be actuated by the pump actuator. Additionally, the heater/mixing container is in fluid communication with the pumping cassette and is sized to be received at the heating pan. The heater/mixing container includes a port configured such that when the port is slid into the slot of the heater pan sidewall, the port is prevented from rotating about an axis transverse to a direction of flow through the port.

First claim

The invention claimed is:

1. A peritoneal dialysis system comprising:
a cycler including a control unit and a pump actuator under control of the control unit; and
a disposable set operable with the cycler, the disposable set including
a pumping cassette having a pump chamber configured to be actuated by the pump actuator, and
a mixing container in fluid communication with the pumping cassette,

wherein the control unit is programmed to promote mixing of at least two fluids by (i) causing the pump actuator to operate the pump chamber to pull the at least two fluids from the mixing container into the pump chamber, (ii) thereafter causing the pump actuator to operate the pump chamber to push the at least two fluids from the pump chamber to the mixing container, and (iii) repeating (i) and (ii) at least one time, and
wherein the mixed at least two fluids form a volume and in (iii), (i) and (ii) are repeated until a certain percentage of the volume is pulled and pushed by the pump chamber.

2. The peritoneal dialysis system of claim 1 , wherein the control unit is configured such that after (i), (ii), and (iii) are performed, a sample of the mixed at least two fluids is caused to undergo a test using a sensor, and wherein at least one of prior to or after the test the sensor is bypassed or used for a different purpose.

3. The peritoneal dialysis system of claim 1 , wherein after (i), (ii), and (iii) are performed, the control unit is configured to cause a sample of the mixed at least two fluids to undergo a test and to cause (i), (ii), and (iii) to be performed at least one additional time when the sample does not pass the test.

4. The peritoneal dialysis system of claim 3 , wherein the test includes comparing a measured property of the sample to a setpoint for the property.

5. The peritoneal dialysis system of claim 1 , wherein the certain percentage of the volume is greater than 100 percent.

6. The peritoneal dialysis system of claim 1 , wherein the pump actuator is a first pump actuator and the pump chamber is a first pump chamber, wherein the cycler includes a second pump actuator under control of the control unit, wherein the pumping cassette has a second pump chamber configured to be actuated by the second pump actuator, and wherein the control unit is programmed to promote mixing of the at least two fluids by (i) causing the first and second pump actuators to simultaneously operate the first and second pump chambers to pull the at least two fluids from the mixing container into the first and second pump chambers, and (ii) thereafter causing the first and second pump actuators to operate the first and second pump chambers to push the at least two fluids from the first and second pump chambers to the mixing container.

7. The peritoneal dialysis system of claim 1 , wherein the mixing container is a heater/mixing bag.

8. A peritoneal dialysis system comprising:
a source of water made suitable for peritoneal dialysis (“WFPD”);
a sensor located at the source of water;
at least one source of concentrate;
a cycler including a control unit and a pump actuator under control of the control unit; and
a disposable set operable with the cycler and in fluid communication with the source of water and the at least one source of concentrate, the disposable set including
a pumping cassette including a pump chamber configured to be actuated by the pump actuator, and
a mixing container in fluid communication with the pumping cassette,

wherein the control unit is programmed to:
mix the WFPD and the at least one concentrate by causing (i) the pump actuator to operate the pump chamber to pump a first amount of the WFPD to the mixing container, (ii) the pump actuator to operate the pump chamber to pump a prescribed amount of the at least one concentrate from the at least one concentrate source to the mixing container, and (iii) the pump actuator to operate the pump chamber to pump a second amount of the WFPD to the mixing container, and
cause a sample of the mixed WFPD and the at least one concentrate to undergo a test using the sensor, wherein the sensor is bypassed or used for a different purpose at least one of prior to or after the test.

9. The peritoneal dialysis system of claim 8 , which includes plural sources of concentrate, and wherein in (ii) the pump actuator operates the pump chamber to pump prescribed amounts of each concentrate from its concentrate source to the mixing container.

10. The peritoneal dialysis system of claim 8 , wherein the prescribed amount of the at least one concentrate is a total amount needed for the at least one concentrate.

11. The peritoneal dialysis system of claim 8 , wherein the first and second amounts of the WFPD add to a total amount needed for the WFPD.

12. The peritoneal dialysis system according to any of claim 8 , wherein the water is made suitable for peritoneal dialysis, at least in part, at the source of water.

Assignees

• Gambro Lundia Ab

Inventors

• Fitzgerald Jane E
• Marry Ryan P
• Norman John S
• Ascenzo James D
• Chen Meng-Yang
• Wellings Anders
• Szpara Edward S
• Jansson Olof

Classifications

• A61M2205/276

  preventing unwanted use · CPC title

• C02F9/00 Primary

  Multistage treatment of water, waste water or sewage · CPC title

• A61M1/1524

  the interface providing means for actuating on functional elements of the cassette, e.g. plungers · CPC title

• A61M1/155

  with treatment-fluid pumping means or components thereof · CPC title

• A61M1/1561

  at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil · CPC title