Modular dialysate regeneration assembly
US-10172991-B2 · Jan 8, 2019 · US
US11925739B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11925739-B2 |
| Application number | US-202017076610-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 21, 2020 |
| Priority date | Oct 23, 2019 |
| Publication date | Mar 12, 2024 |
| Grant date | Mar 12, 2024 |
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An implantable or wearable kidney enclosure that is cylindrical, ovoid, or otherwise non-angular e.g., not rectangular or cuboid), having a circular or oval hemofilter that provides a blood flow pattern from an internal, central artery source radially outwards. Due to the efficient flow of the circular filter design, the enclosure can be made in a cylindrical low profile shape, resulting in a compact enclosure highly suitable for implantable and wearable dialysis applications.
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What is claimed is: 1. An artificial kidney comprising: an annular hemofilter having a circular or oval shape, the hemofilter having a central axis; and an enclosure having a cross-sectional shape corresponding to the hemofilter taken orthogonal to the central axis, the enclosure further having: an interior volume for receiving the annular hemofilter therein, an inlet proximate the central axis fluidly connected to the interior volume to receive a flow of blood therein; an outlet proximate the central axis and fluidly connected to the interior volume to receive a flow of blood therefrom; and a second outlet fluidly connected to the interior volume to receive a flow of toxins therefrom, wherein the inlet is fluidly connected to a first chamber in the enclosure and the outlet is fluidly connected to a second chamber in the enclosure, the first and second chambers separated by the annular hemofilter. 2. The artificial kidney of claim 1 , wherein both the first chamber and the second chamber have a tapering height from the central axis to a periphery of the enclosure. 3. The artificial kidney of claim 2 , wherein the first chamber and the second chamber are symmetrical to each other. 4. The artificial kidney of claim 1 , wherein the enclosure is radially symmetrical about the central axis. 5. The artificial kidney of claim 1 further comprising a second inlet proximate the central axis fluidly connected to the interior volume to receive a flow of dialysate therein. 6. The artificial kidney of claim 5 , wherein the second outlet is proximate the central axis and fluidly connected to the second inlet. 7. The artificial kidney of claim 1 comprising a plurality of annular hemofilter pairs connected in series. 8. The artificial kidney of claim 1 comprising a plurality of annular hemofilter pairs connected in parallel. 9. An artificial kidney comprising: an annular hemofilter having a circular or oval shape, the annular hemofilter having an inner diameter and an outer diameter; and an enclosure having a shape corresponding to the hemofilter, the enclosure having a thickness, a diameter, and an interior volume for receiving and enclosing the hemofilter therein, with the enclosure thickness less than the enclosure diameter, the enclosure having a blood inlet, and a blood outlet proximate a central axis; the artificial kidney having a radial blood flow path across the annular hemofilter from the inner diameter to the outer diameter. 10. The artificial kidney of claim 9 further comprising a blood inlet centrally located in the enclosure and fluidly connected to the interior volume. 11. The artificial kidney of claim 10 further comprising a dialysate inlet centrally located in the enclosure and fluidly connected to the interior volume. 12. The artificial kidney of claim 10 wherein the blood inlet is fluidly connected to a first chamber in the enclosure and a blood outlet is fluidly connected to a second chamber in the enclosure, the first and second chambers separated by the annular hemofilter. 13. The artificial kidney of claim 12 , wherein both the first chamber and the second chamber have a tapering height from the inner diameter to the outer diameter. 14. The artificial kidney of claim 12 comprising a plurality of annular hemofilter pairs connected in series. 15. The artificial kidney of claim 12 comprising a plurality of annular hemofilter pairs connected in parallel.
characterised by the shape · CPC title
Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration · CPC title
having non-tubular membranes, e.g. sheets · CPC title
with more than one dialyser unit · CPC title
Dialysates therefor · CPC title
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