Anti-inflammatory peptides and composition comprising the same

US11905536B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11905536-B2
Application numberUS-202117389671-A
CountryUS
Kind codeB2
Filing dateJul 30, 2021
Priority dateJul 20, 2012
Publication dateFeb 20, 2024
Grant dateFeb 20, 2024

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprising the above mentioned peptides. According to the present invention, a peptide that has at least one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161 has outstanding efficacy in both suppressing inflammation and in prophylactic means. Therefore, the composition comprising the peptides of this invention can be used as anti-inflammatory pharmaceutical compositions or as cosmetic compositions, in turn, treating and preventing a variety of different types of inflammatory diseases.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of treating or preventing inflammatory disease in a patient, comprising administering to the patient an isolated peptide having anti-inflammatory activity, wherein the peptide consists of the amino acid sequence of SEQ ID NO: 73 or SEQ ID NO: 130. 2. The method according to claim 1 , wherein the inflammatory disease is general or localized inflammatory disease; gastro-intestinal related diseases; dermal related diseases; vascular related disease; respiratory diseases; bone, joint, muscle, and connective tissue related diseases; urogenital disorders; central or peripheral nervous system related diseases; virus; or autoimmune diseases. 3. The method according to claim 1 , wherein the daily dose of the peptide is 0.1 μg/kg/day to 1 g/kg/day. 4. A method of treating or preventing skin inflammation comprising administering an isolated peptide having anti-inflammatory activity, wherein the peptide consists of the amino acid sequence of SEQ ID NO: 73 or SEQ ID NO: 130. 5. The method according to claim 4 , wherein the daily dose of the peptide is 0.1 μg/kg/day to 1 g/kg/day. 6. The method according to claim 2 , wherein the central or peripheral nervous system related disease is Alzheimer's disease; meningitis; encephalitis; multiple sclerosis; cerebral infarction; cerebral embolism; Guillain-Barre syndrome; neuritis; neuralgia; spinal cord injury; paralysis; or uveitis.

Assignees

Inventors

Classifications

  • C12N9/1276Primary

    RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase · CPC title

  • Peptides; Protein hydrolysates · CPC title

  • Transferases (2) · CPC title

  • Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

  • RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase · CPC title

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What does patent US11905536B2 cover?
The present invention relates to a peptide with anti-inflammatory activity, wherein the peptide comprises any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 161, the peptide has above 80% homology of amino acid sequence with above-mentioned sequences, or the peptide is the fragment of the above-mentioned peptides. The present invention also relates to an inflammatory composition comprisi…
Who is the assignee on this patent?
Gemvax & Kael Co Ltd, Kim Sang Jae
What technology area does this patent fall under?
Primary CPC classification C12N9/1276. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Feb 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).