Cell-permeable peptide
US-9023987-B2 · May 5, 2015 · US
Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate
US9572900B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9572900-B2 |
| Application number | US-201314429644-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 17, 2013 |
| Priority date | Sep 19, 2012 |
| Publication date | Feb 21, 2017 |
| Grant date | Feb 21, 2017 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 2 to SEQ ID NO: 178, a fragment of any one sequence of SEQ ID NO: 2 to SEQ ID NO: 178, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.
First claim
Opening claim text (preview).
What is claimed is: 1. A conjugate comprising a cell penetrating carrier peptide and an active ingredient, wherein the carrier peptide is 12 amino acids in length and consists of the amino acid sequence of SEQ ID NO: 105. 2. The conjugate according to claim 1 , wherein the active ingredient is a protein, nucleic acid, peptide, lipid, mineral, sugar, nano-particle, contrast agent, or drug. 3. The conjugate according to claim 1 , wherein the carrier peptide is bonded to the active ingredient via a covalent bond and optionally mediated by a linker. 4. The conjugate according to claim 1 , wherein the carrier peptide is bonded to the active ingredient via a non-covalent bond. 5. The conjugate according to claim 2 , wherein the active ingredient is a protein or a peptide. 6. The conjugate according to claim 5 , wherein the active ingredient is a cytokine, antibody, fragment of antibody, therapeutic enzyme, soluble receptor or ligand. 7. The conjugate according to claim 2 , wherein the contrast agent is selected from the group consisting of radiopaque contrast agent, paramagnetic contrast agent, superparamagnetic contrast agent and computed tomography (CT) contrast agent. 8. The conjugate according, to claim 2 , wherein the contrast agent comprises iron. 9. The conjugate according to claim 8 , wherein the contrast agent is a ferrocene carboxylate. 10. A contrast agent comprising the conjugate of claim 1 . 11. A cell comprising the contrast agent according to claim 10 . 12. The cell according to claim 11 , wherein the cell is a stem cell. 13. A composition comprising the conjugate according to claim 1 as an active ingredient; wherein the composition is selected from a pharmaceutical composition, a cosmetic composition, and a health food composition. 14. The composition according to claim 13 , wherein the composition is a pharmaceutical composition. 15. The composition according to claim 13 , wherein the composition is a cosmetic composition. 16. The composition according to claim 13 , wherein the composition is a health food composition. 17. A cell penetrating carrier peptide that is 12 amino acids in length and consists of the amino acid sequence of SEQ ID NO: 105.
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Antineoplastic agents · CPC title
Immunomodulators · CPC title
specific for leukemia · CPC title
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9572900B2 cover?
- The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 2 to SEQ ID NO: 178, a fragment of any one sequence of SEQ ID NO: 2 to SEQ ID NO: 178, or a peptide having above 80% homology with the above-mentioned…
- Who is the assignee on this patent?
- Gemvax & Kael Co Ltd, Kim Sang Jae
- What technology area does this patent fall under?
- Primary CPC classification C12N9/1276. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 21 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).