Vital signs monitor

Patent metadata

Field	Value
Publication number	US-11864872-B2
Application number	US-202117156235-A
Country	US
Kind code	B2
Filing date	Jan 22, 2021
Priority date	Mar 31, 2016
Publication date	Jan 9, 2024
Grant date	Jan 9, 2024

Abstract

A method of estimating a continuous blood pressure waveform or a continuous blood pressure in a subject including: measuring an arterial blood pressure waveform or an arterial blood pressure with a sensor supported by a supporting structure comprising a polymeric substrate and connected to a processor and a transmitter, wherein the supporting structure is configured to press the sensor against a skin surface of a subject, wherein the sensor is configured to detect a biological metric of the subject, and wherein the processor is configured to quantify one or more signal(s) corresponding to the biological metric and the transmitter is configured to transmit the one or more signals to an external user system, and transforming the arterial blood pressure waveform or the arterial blood pressure to the continuous blood pressure waveform or the continuous blood pressure using a transfer function.

First claim

What is claimed is:

1. A method of estimating a continuous blood pressure waveform in a subject comprising:
measuring an arterial blood pressure waveform with a sensor supported by a supporting structure comprising a polymeric substrate and connected to a processor and a transmitter, wherein the supporting structure is configured to press the sensor against a skin surface of a subject, wherein the sensor is configured to detect a biological metric of the subject, and wherein the processor is configured to quantify one or more signal(s) corresponding to the biological metric and the transmitter is configured to transmit the one or more signals to an external user system, and
transforming the arterial blood pressure waveform to the continuous blood pressure waveform using a transfer function.

2. The method of claim 1 , wherein the sensor is a capacitive sensor.

3. The method of claim 1 , wherein the arterial pressure is transformed to a blood pressure of a different site using the transfer function.

4. The method of claim 1 , wherein a radial arterial pressure is transformed to a central aortic blood pressure, a brachial blood pressure.

5. The method according to claim 1 , wherein the transfer function describes the properties of a system on the basis of its immediate past input and output data.

6. The method according to claim 5 , wherein the transfer function uses the relation:
T ( t )=− a 1 T ( t− 1)− a 2 T ( t− 2)− . . . − anaT ( T ( t−na )+ b 1 P ( t− 1)+ . . . + bnbP ( t−nb )  (1)

where T(t) and T(t−I) [I=1, 2 . . . na] are present and are previous output (radial tonometer) discrete measurements, respectively, and P(t−I) are previous input (aortic pressure) discrete measurements, a1, a2, ana and bnb are parameters of the model, and na and nb represent a number of previous input-output values used to describe the present output.

7. The method according to claim 1 , wherein the wearable device further comprises:
memory, and
a battery.

8. The method according to claim 7 , wherein the processor, memory, battery and transmitter are comprised within a housing disposed on an inner or an outer side of the supporting structure.

9. The method according to claim 7 , wherein the transfer function describes the properties of a system on the basis of its immediate past input and output data.

10. The method according to claim 9 , wherein the transfer function uses the relation:
T ( t )=− a 1 T ( t− 1)− a 2 T ( t− 2)− . . . − anaT ( T ( t−na )+ b 1 P ( t− 1)+ . . . + bnbP ( t−nb )  (1)

where T(t) and T(t−I) [I=1, 2 . . . na] are present and are previous output (radial tonometer) discrete measurements, respectively, and P(t−I) are previous input (aortic pressure) discrete measurements, a1, a2, ana and bnb are parameters of the model, and na and nb represent a number of previous input-output values used to describe the present output.

11. The method of claim 1 , wherein the continuous blood pressure waveform comprises a systolic blood pressure waveform.

12. The method of claim 1 , wherein the continuous blood pressure waveform comprises a diastolic blood pressure waveform.

Assignees

• Univ California

Inventors

• Khine Michelle
• Eckmann Nicole
• Veliz Kimberly
• Pegan Jonathan
• Kim Joshua
• Park Sun-Jun

Classifications

• A61B5/02055 Primary

  Simultaneously evaluating both cardiovascular condition and temperature · CPC title

• A61B5/6824

  Arm or wrist · CPC title

• A61B5/021

  Measuring pressure in heart or blood vessels · CPC title

• A61B5/024

  Measuring pulse rate or heart rate · CPC title

• A61B5/0816

  Measuring devices for examining respiratory frequency (measuring frequency of electric signals G01R23/00) · CPC title