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US-11118163-B2 · Sep 14, 2021 · US
Host-guest metal organic framework systems
US11840580B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11840580-B2 |
| Application number | US-202117165523-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 2, 2021 |
| Priority date | Jul 3, 2014 |
| Publication date | Dec 12, 2023 |
| Grant date | Dec 12, 2023 |
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- Title
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- Abstract
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Abstract
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A method for producing Metal Organic Framework (MOF) having a framework that encapsulates a bio-molecule, the method comprising combining in a solution the bio-molecule and MOF precursors, wherein the bio-molecule promotes formation of the encapsulating framework.
First claim
Opening claim text (preview).
The invention claimed is: 1. A crystalline Metal Organic framework (MOF) having a framework that defines intrinsic cavities and encapsulates a bio-molecule, wherein the framework-is formed around the bio-molecule, wherein the bio-molecule is a protein, a nucleic acid, an amino acid, or a combination thereof, wherein the biomolecule has a smallest dimension that is at least 1.5 times larger than the largest cavity diameter (LCD) of any intrinsic cavity of the framework, and wherein the bio-molecule sits within the MOF as a bioactive, heterogenous and discontinuous guest phase within a self-defined cavity. 2. The MOF according to claim 1 , wherein the bio-molecule is a protein which is an enzyme. 3. The MOF according to claim 1 , wherein the framework encapsulates from 1% wt to 32% wt bio-molecule relative to the weight of the MOF framework. 4. The MOF according to claim 1 , wherein the LCD is between 5 Å and 500 Å.
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Inventors
Classifications
- C07K17/04Primary
entrapped within the carrier, e.g. gel, hollow fibre · CPC title
- A61K9/501Primary
Inorganic compounds · CPC title
inclusion complexes, e.g. clathrates, cavitates or fullerenes · CPC title
Zinc compounds · CPC title
Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12 (esters with inorganic acids C07H11/00) · CPC title
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Frequently asked questions
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- What does patent US11840580B2 cover?
- A method for producing Metal Organic Framework (MOF) having a framework that encapsulates a bio-molecule, the method comprising combining in a solution the bio-molecule and MOF precursors, wherein the bio-molecule promotes formation of the encapsulating framework.
- Who is the assignee on this patent?
- Commw Scient Ind Res Org
- What technology area does this patent fall under?
- Primary CPC classification C07K17/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).