Drug reconstitution system

Patent metadata

Field	Value
Publication number	US-11833110-B2
Application number	US-202017114004-A
Country	US
Kind code	B2
Filing date	Dec 7, 2020
Priority date	Mar 8, 2012
Publication date	Dec 5, 2023
Grant date	Dec 5, 2023

Abstract

A system including an adapter for sequential engagement with a cartridge containing a first substance and a vial containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member engageable with a portion of the cartridge. A plunger rod includes a protrusion and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.

First claim

What is claimed is:

1. A system comprising:
a cartridge holder having a cartridge holder distal end, a cartridge holder proximal end, and a sidewall extending therebetween and defining a chamber having an interior adapted to receive a cartridge therein;
a stopper slidably disposed within the chamber; and
a latch member engageable with a portion of the cartridge holder and a portion of a plunger rod, wherein the latch member comprises an annular body and a rocker pivotally mounted to the annular body, the rocker comprising an upper arm engageable with the portion of the cartridge holder and a lower arm engageable with the portion of the plunger rod,
wherein the plunger rod is engageable with a portion of the stopper and adapted to communicate with the latch member, the plunger rod comprising a protrusion, and
wherein the plunger rod is transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge holder, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge holder and locked to the plunger rod.

2. The system of claim 1 , wherein the plunger rod further comprises a plunger rod distal end engageable with the portion of the stopper and a plunger rod proximal end, the protrusion extending from the plunger rod adjacent the plunger rod proximal end.

3. The system of claim 1 , wherein, with the plunger rod in the disengaged position, the latch member is locked to the cartridge holder proximal end.

4. The system of claim 3 , wherein the stopper is slidably disposed within the interior of the chamber between a first position adjacent the cartridge holder proximal end and a second position adjacent the cartridge holder distal end.

5. The system of claim 4 , wherein, with the stopper in the first position, the plunger rod is in the disengaged position.

6. The system of claim 4 , wherein, with the stopper in the second position, the plunger rod is in the engaged position.

7. The system of claim 1 , wherein a portion of the plunger rod is sized for movement within the interior of the chamber from the disengaged position to the engaged position.

8. The system of claim 1 , further comprising a first substance contained within the chamber of the cartridge holder.

9. The system of claim 1 , wherein movement of the plunger rod in a distal direction through the annular body of the latch member causes the plunger rod to transition from the disengaged position to the engaged position.

10. The system of claim 9 , wherein the movement of the plunger rod in the distal direction causes the rocker to pivot about a connection point with the annular body.

11. The system of claim 1 , wherein the annular body of the latch member is secured or locked to the cartridge holder by rotating the annular body of the latch member relative to the cartridge holder, which moves the upper arm of the rocker into a recess in the sidewall of the cartridge holder.

12. The system of claim 1 , wherein, in the disengaged position, the protrusion of the plunger rod is disengaged from the lower arm of the rocker and the upper arm of the rocker is locked to the cartridge holder, and, in the engaged position, the protrusion is engaged with the lower arm of the rocker and the upper arm of the rocker is unlocked from the cartridge holder and locked to the plunger rod.

13. The system of claim 12 , wherein, as the plunger rod transitions from the disengaged position to the engaged position, the rocker pivots relative to the annular body of the latch member to allow the protrusion to slide past the lower arm of the latch member, such that the latch member is unlocked from the cartridge holder and the lower arm locks to the protrusion of the plunger rod.

14. A system comprising:
a cartridge holder having a cartridge holder distal end, a cartridge holder proximal end, and a sidewall extending therebetween and defining a chamber having an interior adapted to receive a cartridge therein;
a stopper slidably disposed within the interior of the chamber of the cartridge holder;
a locking member connected to the cartridge holder and adapted to prevent the stopper from sliding out of the cartridge holder; and
a plunger rod having a plunger rod distal end engageable with a portion of the stopper, a plunger rod proximal end, and a deformable restraining member transitionable between a deformed position to an undeformed position, a portion of the plunger rod sized for movement within the interior of the chamber of the cartridge holder to actuate the stopper, wherein, with the plunger rod in an initial position, the locking member deforms the restraining member of the plunger rod so that the plunger rod is capable of actuating the stopper.

15. The system of claim 14 , wherein:
the stopper defines a stopper outer diameter; and
the locking member defines a locking member inner diameter, the locking member inner diameter is less than the stopper outer diameter, thereby the locking member provides a physical barrier preventing the stopper from sliding out of the cartridge holder.

16. The system of claim 14 , wherein the locking member is connected adjacent to the cartridge holder proximal end.

17. The system of claim 14 , wherein, after the plunger rod actuates the stopper, as the restraining member of the plunger rod is advanced beyond the locking member, the restraining member of the plunger rod moves to its undeformed position and locks to the locking member, thereby the locking member prevents the plunger rod from actuating the stopper again.

Assignees

• Becton Dickinson Co

Inventors

• Cronenberg Richard
• Wu Haiming

Classifications

• A61J1/2048 Primary

  Connecting means · CPC title

• A61J1/2013

  having two piercing ends · CPC title

• A61M5/19

  having more than one chamber {, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly (surgical glue applicators A61B17/00491)} · CPC title

• A61M5/24 Primary

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title

• A61M5/2448

  comprising means for injection of two or more media, e.g. by mixing · CPC title