Drug reconstitution system

Patent metadata

Field	Value
Publication number	US-9950119-B2
Application number	US-201314377585-A
Country	US
Kind code	B2
Filing date	Mar 8, 2013
Priority date	Mar 8, 2012
Publication date	Apr 24, 2018
Grant date	Apr 24, 2018

Abstract

A system including an adapter ( 14 ) for sequential engagement with a cartridge ( 18 ) containing a first substance and a vial ( 16 ) containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member ( 150 ) engageable with a portion of the cartridge. A plunger rod ( 44 ) includes a protrusion ( 50 ) and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.

First claim

What is claimed is:

1. A system comprising:
a cartridge holder having a cartridge holder distal end, a cartridge holder proximal end, and a sidewall extending therebetween and defining an interior adapted to receive a cartridge defining a cartridge chamber;
a first substance contained within the cartridge chamber;
a stopper slidably disposed within the cartridge chamber;
a latch member engageable with a portion of the cartridge holder and a first portion of a plunger rod, wherein the plunger rod is engageable with a portion of the stopper and adapted to communicate with the latch member, the plunger rod comprising a protrusion, wherein the plunger rod is transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge holder, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge holder and locked to the plunger rod;
a vial defining a vial chamber;
a second substance contained within the vial chamber; and
an adapter having a first end adapted to engage the vial and a second end adapted to engage the cartridge holder after engagement with the vial.

2. The system of claim 1 ,
wherein the plunger rod is transitionable from the disengaged position to the engaged position upon distal movement of the plunger rod.

3. The system of claim 1 , wherein the plunger rod further comprises a plunger rod distal end engageable with the portion of the stopper and a plunger rod proximal end, the protrusion extending from the plunger rod adjacent the plunger rod proximal end.

4. The system of claim 1 , wherein with the plunger rod in the disengaged position, the latch member is locked to the cartridge holder proximal end.

5. The system of claim 4 , wherein the stopper is transitionable between a first position adjacent the cartridge holder proximal end and a second position adjacent the cartridge holder distal end.

6. The system of claim 5 , wherein with the stopper in the first position the plunger rod is in the disengaged position.

7. The system of claim 5 , wherein with the stopper in the second position the plunger rod is in the engaged position.

8. The system of claim 5 , wherein actuation of the stopper from the first position to the second position by the plunger rod expels the first substance from the cartridge chamber to the vial chamber via the adapter.

9. The system of claim 1 , wherein a second portion of the plunger rod is sized for movement within an interior of the cartridge from the disengaged position to the engaged position.

10. The system of claim 1 , wherein the adapter is adapted to engage with the vial and the cartridge holder prior to establishment of fluid communication with the vial or with the cartridge.

11. The system of claim 1 , wherein with the vial engaged with the adapter, the adapter is adapted to engage with the cartridge holder such that the cartridge chamber is in fluid communication with the vial chamber via the adapter.

12. The system of claim 11 , wherein the stopper is adapted to expel the first substance from the cartridge chamber to the vial chamber via the adapter.

13. The system of claim 1 , wherein the first substance comprises a diluent.

14. The system of claim 1 , wherein the second substance comprises a powder.

Assignees

• Becton Dickinson Co

Inventors

• Cronenberg Richard
• Wu Haiming

Classifications

• A61J1/2048 Primary

  Connecting means · CPC title

• A61M2005/31508

  provided on the piston-rod · CPC title

• A61M5/24 Primary

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title

• A61M5/2448

  comprising means for injection of two or more media, e.g. by mixing · CPC title

• A61M5/31505 Primary

  Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit · CPC title