Plasma treatment apparatus for producing coatings

Patent metadata

Field	Value
Publication number	US-11772128-B2
Application number	US-202016854523-A
Country	US
Kind code	B2
Filing date	Apr 21, 2020
Priority date	Jan 20, 2011
Publication date	Oct 3, 2023
Grant date	Oct 3, 2023

Abstract

An apparatus and to a method for treating layers using a plasma zone sealed from the outer atmospheric pressure are provided. The apparatus and method include a plasma reactor including a substrate carrier in form of a container receiving means, and a closing element that is joined with the substrate carrier by means of a lifting device.

First claim

The invention claimed is:

1. A pharmaceutical container, comprising:
a wall having an inner surface;
an intermediate layer on the inner surface;
a lubricating layer that a cross-linked organic film and is silicone free on the intermediate layer, the intermediate layer adhering the lubricating layer on the inner surface; and
a stopper in contact with the lubricating layer,
wherein the stopper has an initial breakaway force with respect to the lubricating layer that is in a range from 9 N to 10 N,
wherein the stopper has a sliding force with respect to the lubricating layer from 1 N to 4 N and the sliding force is stable within 7 days of storage at 40° while the pharmaceutical container is filled with water.

2. The pharmaceutical container of claim 1 , wherein the sliding force is stable within 28 days of storage at 40° while the pharmaceutical container is filled with water.

3. The pharmaceutical container of claim 1 , wherein the sliding force does not vary more than 50% before and after storage.

4. The pharmaceutical container of claim 1 , wherein the wall comprises a material selected from a group consisting of glass, cycloolefin copolymers (COC), cyclo-olefin polymers (COP), HDPE, MDPE, LDPE, polypropylene, and borosilicate glass.

5. The pharmaceutical container of claim 1 , wherein the stopper has a breakaway force with respect to the lubricating layer that is, after storage for 7 days at 40° C. while the pharmaceutical container is filled with water, greater than 0 N and at most 15 N.

6. The pharmaceutical container of claim 1 , wherein the stopper has a breakaway force with respect to the lubricating layer that is, after storage for 28 days at 40° while the pharmaceutical container is filled with water, greater than 0N and at most 17N.

7. The pharmaceutical container of claim 1 , wherein the intermediate layer is a crosslinked organic film.

8. The pharmaceutical container of claim 7 , wherein the crosslinked organic film comprises a material selected from a group consisting of perfluoropolyether (PFPE), perfluorosiloxane, PTFE particles, mineral oil, vegetable oil, animal based oil, synthetic fluid hydrocarbons, fluid fluorinated or chlorinated hydrocarbons, organic esters, fatty acid esters, polyphenylethers, phosphoric acid esters, polyethylene glycol, polyalkylene glycols, polyalphaolefin, polyaromatic hydrocarbon, alkylbenzenes, polyurethanes, squalene, and combinations thereof.

9. A pharmaceutical container, comprising:
a wall with an inner surface coated with an intermediate layer and a lubricating layer that is silicone free on the intermediate layer, the intermediate layer adhering the lubricating layer to the inner surface; and
a stopper in contact with the lubricating layer;
an initial breakaway force of the stopper with respect to the lubricating layer that is in a range from 9 N to 10 N; and
a sliding force of the stopper with respect to the lubricating layer, wherein the sliding force is less than 5N.

10. The pharmaceutical container of claim 9 , wherein the sliding force is stable within 7 days of storage at 40° C. while the pharmaceutical container is filled with water.

11. The pharmaceutical container of claim 9 , wherein the sliding force is stable within 28 days of storage at 40° C. while the pharmaceutical container is filled with water.

12. The pharmaceutical container of claim 9 , wherein the stopper has a breakaway force with respect to the lubricating layer, wherein the breakaway force does not increase more than 100% within 7 days of storage at 40° C. while the pharmaceutical container is filled with water.

13. The pharmaceutical container of claim 9 , wherein the stopper has a breakaway force with respect to the lubricating layer, wherein the breakaway force does not increase more than 100% within 28 days of storage at 40° C. while the pharmaceutical container is filled with water.

14. Pharmaceutical packaging, comprising a plurality of a pharmaceutical containers, each of the plurality of a pharmaceutical containers comprising:
a wall with an inner surface coated with an intermediate layer and a lubricating layer that is silicone free on the intermediate layer, the intermediate layer adhering the lubricating layer to the inner surface; and
a stopper in contact with the lubricating layer; and
a sliding force of the stopper with respect to the lubricating layer,
wherein the sliding force of each of the plurality of pharmaceutical containers is less than 5 N, and
wherein the stopper has an initial breakaway force with respect to the lubricating layer that is in a range from 9 N to 10 N.

15. The pharmaceutical packaging of claim 14 , wherein the sliding force of each of the plurality of pharmaceutical containers is stable within 7 days of storage at 40° C. while the pharmaceutical container is filled with water.

16. The pharmaceutical packaging of claim 14 , wherein the sliding force of each of the plurality of pharmaceutical containers is stable within 28 days of storage at 40° C. while the pharmaceutical container is filled with water.

17. The pharmaceutical packaging of claim 14 , wherein the plurality of pharmaceutical containers comprise four pharmaceutical containers.

Assignees

• Schott Ag

Inventors

• Bicker Matthias
• Lohmeyer Manfred
• Bauch Hartmut

Classifications

• B05D3/147 Primary

  Curing · CPC title

• A61M5/3129

  Syringe barrels (A61M5/3205 and A61M5/50 take precedence) · CPC title

• B05D1/62 Primary

  Plasma-deposition of organic layers (plasma deposition in general C23C14/00, C23C16/00) · CPC title

• B05D7/22

  to internal surfaces, e.g. of tubes · CPC title

• C03C17/004

  Coating the inside · CPC title