Electrical stimulation with thermal treatment or thermal monitoring

Patent metadata

Field	Value
Publication number	US-11712561-B2
Application number	US-202016855448-A
Country	US
Kind code	B2
Filing date	Apr 22, 2020
Priority date	Apr 23, 2019
Publication date	Aug 1, 2023
Grant date	Aug 1, 2023

Abstract

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit configured to generate one or more electric fields and a control circuit in communication with the electric field generating circuit. The control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit. The system can include two or more electrodes to deliver the electric fields to a site of a cancerous tumor within a patient and a temperature sensor to measure the temperature of tissue at the site of the cancerous tumor. The control circuit can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.

First claim

The invention claimed is:

1. A medical device system comprising:
an electric field generating circuit configured to generate one or more electric fields; and
a control circuit in communication with the electric field generating circuit, the control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit;
two or more electrodes forming at least one electrode pair to deliver the one or more electric fields to a site of a cancerous tumor within a patient; and
wherein the control circuit causes the electric field generating circuit to generate the one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz, wherein the one or more electric fields are effective to disrupt cellular mitosis in a cancerous cell;
wherein the control circuit calculates a power output of the one or more electric fields and estimates a temperature of tissue within the one or more electric fields based on the power output and a distance between the two or more electrodes of the at least one electrode pair;
wherein the temperature of the tissue is estimated by dividing an average power output by the product of the distance between the two or more electrodes and a specific heat capacity of the tissue.

2. The medical device system of claim 1 , wherein the medical device system is configured to receive data regarding the distance between the two or more electrodes of the at least one electrode pair.

3. The medical device system of claim 1 , wherein the medical device system is configured to estimate the distance between the two or more electrodes of the at least one electrode pair based on impedance data.

4. The medical device system of claim 2 , wherein the medical device system receives the data regarding the distance between the two more electrodes from a user.

5. The medical device system of claim 4 , wherein the user determines the distance between the two or more electrodes using equipment selected from the group consisting of an imaging device, a fluoroscope, and an ultrasound imaging device.

Assignees

• Boston Scient Scimed Inc

Inventors

• Schmidt Brian L
• Stein Benjamin Keith
• Maile Keith R
• Linder William J
• Kharam Aleksandra

Classifications

• A61N1/36002 Primary

  Cancer treatment, e.g. tumour · CPC title

• A61F7/007

  characterised by electric heating · CPC title

• A61F2007/0073

  thermistor · CPC title

• A61F2007/0096

  with a thermometer · CPC title

• A61N1/06

  for high-frequency therapy · CPC title