Implantable blood pump assembly including pressure sensor and methods of assembling same

Patent metadata

Field	Value
Publication number	US-11684769-B2
Application number	US-201916721432-A
Country	US
Kind code	B2
Filing date	Dec 19, 2019
Priority date	Dec 21, 2018
Publication date	Jun 27, 2023
Grant date	Jun 27, 2023

Abstract

Disclosed herein is an implantable blood pump assembly that includes a housing defining an inlet, an outlet, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path. The blood pump assembly further includes a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet, a stator positioned within the internal compartment and operable to drive the rotor, and an inlet conduit connected to the housing inlet and having a downstream end that has a reduced cross-sectional area that produces a localized region of high velocity blood flow. The blood pump assembly further includes at least one pressure sensor positioned between the inlet and the outlet and configured to detect a pressure of blood flowing through the flow path. The pressure sensor is located adjacent the downstream end of the inlet conduit.

First claim

What is claimed is:

1. An implantable blood pump assembly comprising:
a housing defining an inlet, an outlet, a rotor chamber, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path;
a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet;
a stator positioned within the internal compartment and operable to drive the rotor;
an inlet conduit connected to the housing inlet, the inlet conduit having a downstream end having a reduced cross-sectional area that produces a localized region of high velocity blood flow, the downstream end terminating at an outlet of the inlet conduit; and
at least one pressure sensor positioned between the housing inlet and the housing outlet and configured to detect a pressure of blood flowing through the flow path, wherein the at least one pressure sensor is located adjacent the downstream end of the inlet conduit, and between the outlet of the inlet conduit and the rotor chamber.

2. The implantable blood pump assembly of claim 1 further comprising a sensor assembly, the sensor assembly comprising the at least one pressure sensor and a housing, the at least one pressure sensor positioned within the sensor assembly housing.

3. The implantable blood pump assembly of claim 2 , wherein the sensor assembly housing defines a sensor assembly flow path concentric with the downstream end of the inlet conduit, the sensor assembly housing further comprising a flexible membrane that transmits fluid pressure of blood flowing through the sensor assembly flow path to the at least one pressure sensor.

4. The implantable blood pump assembly of claim 2 , wherein the sensor assembly housing comprises a sleeve that extends upstream from the sensor assembly housing, wherein the downstream end of the inlet conduit is positioned within the sleeve.

5. The implantable blood pump assembly of claim 2 , wherein the at least one pressure sensor comprises a first pressure sensor and a second pressure sensor, wherein the first and second pressure sensors are positioned within the sensor assembly housing diametrically opposite one another.

6. The implantable blood pump assembly of claim 1 , wherein the at least one pressure sensor is positioned within the internal compartment.

7. The implantable blood pump assembly of claim 1 , wherein the at least one pressure sensor comprises a sensing element and a deflectable membrane positioned between the sensing element and the flow path.

8. The implantable blood pump assembly of claim 7 , wherein the sensing element comprises at least one of a capacitive pressure sensing element or a piezo-resistive pressure sensing element.

9. The implantable blood pump assembly of claim 1 further comprising a controller connected to the at least one pressure sensor and the stator and positioned within the internal compartment, wherein the controller is configured to control a rotational speed of the rotor based on the pressure detected by the at least one pressure sensor.

10. The implantable blood pump assembly of claim 9 , wherein the at least one pressure sensor is directly connected to the controller for receiving power therefrom and sending pressure measurement signals thereto.

11. The implantable blood pump assembly of claim 1 , wherein the implantable blood pump assembly is configured as a centrifugal pump.

12. The implantable blood pump assembly of claim 1 , wherein the rotor comprises a permanent magnet, and wherein the stator is operable to drive the rotor by generating an electromagnetic field that interacts with the permanent magnet of the rotor.

13. A circulatory support system comprising:
an implantable blood pump comprising:
a housing defining an inlet, an outlet, a rotor chamber, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path;
a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet;
a stator positioned within the internal compartment and operable to drive the rotor;
an inlet conduit connected to the housing inlet, the inlet conduit having a downstream end having a reduced cross-sectional area that produces a localized region of high velocity blood flow, the downstream end terminating at an outlet of the inlet conduit; and
at least one pressure sensor positioned between the housing inlet and the housing outlet and configured to detect a pressure of blood flowing through the flow path, wherein the at least one pressure sensor is located adjacent the downstream end of the inlet conduit, and between the outlet of the inlet conduit and the rotor chamber; and

a controller connected to the at least one pressure sensor and the stator and positioned within the internal compartment, wherein the controller is configured to control a rotational speed of the rotor based on the pressure detected by the at least one pressure sensor.

14. The circulatory support system of claim 13 , wherein the at least one pressure sensor is directly connected to the controller for receiving power therefrom and sending pressure measurement signals thereto.

15. The circulatory support system of claim 13 further comprising an external system controller operatively connected to the blood pump for receiving pressure measurement data therefrom, wherein the external system controller comprises an atmospheric pressure sensor for detecting an ambient pressure, wherein the external system controller is configured to determine a gauge pressure based on the pressure measurement data and the ambient pressure.

16. A method of assembling a blood pump assembly, the method comprising:
providing a blood pump housing defining an inlet, an outlet, a rotor chamber, a flow path extending from the inlet to the outlet, and an internal compartment;
positioning a rotor within the flow path such that the rotor is operable to pump blood from the inlet to the outlet;
positioning a stator within the internal compartment such that the stator is operable to drive the rotor;
connecting a downstream end of an inlet conduit to the housing inlet, the downstream end having a reduced cross-sectional area that produces a localized region of high velocity blood flow, the downstream end terminating at an outlet of the inlet conduit; and
positioning at least one pressure sensor between the housing inlet and the housing outlet, adjacent to the downstream end of the inlet conduit, and between the outlet of the inlet conduit and the rotor chamber such that the at least one pressure sensor is configured to detect a pressure of blood flowing through the flow path.

17. The method of claim 16 , wherein positioning at least one pressure sensor between the inlet and the outlet includes connecting a sensor assembly to the blood pump housing, the sensor assembly including a housing, wherein the at least one pressure sensor is positioned within the sensor assembly housing.

18. The method of claim 17 , wherein the sensor assembly housing includes a sleeve that extends upstream from the sensor assembly housing, wherein connecting a downstream end of an inlet conduit to the housing inlet includes positioning the downstream end of the inlet conduit within the sleeve.

Assignees

• Tc1 Llc

Inventors

• Harjes Daniel I
• Lee Eric
• Park Jin Woo

Classifications

• A61M60/148

  in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices · CPC title

• A61M2205/0294

  Piezoelectric materials · CPC title

• A61M60/816

  Sensors arranged on or in the housing, e.g. ultrasonic flow sensors · CPC title

• A61M2205/103

  rotating · CPC title

• A61M2205/3365

  Rotational speed · CPC title