Venous valve prostheses

Patent metadata

Field	Value
Publication number	US-11684476-B2
Application number	US-202117194973-A
Country	US
Kind code	B2
Filing date	Mar 8, 2021
Priority date	Dec 3, 2015
Publication date	Jun 27, 2023
Grant date	Jun 27, 2023

Abstract

A venous valve prosthesis includes a frame and a prosthetic valve coupled to the frame. With the venous valve prosthesis implanted in a vein, the prosthetic valve includes a closed configuration wherein an outer surface of the prosthetic valve is in contact with a wall of the vein around a circumference of the prosthetic valve to prevent blood from flowing past the prosthetic valve between the wall of the vein and the outer surface of the prosthetic valve. The prosthetic valve is configured to move to an open configuration such that at least a portion of an outer wall of the prosthetic valve partially collapses away from the wall of the vein in response to antegrade blood flow through the vein to enable blood flow between the outer surface of the prosthetic valve and the wall of the vein.

First claim

What is claimed is:

1. A venous valve prosthesis comprising:
a frame defining a longitudinal axis; and
a prosthetic valve coupled to the frame and disposed about an exterior of the frame, the prosthetic valve defining an outer surface and an inner surface and one or more slits extending from the outer surface to the inner surface, the prosthetic valve having a closed configuration wherein the one or more slits are closed and an open configuration wherein the one or more slits are open,
wherein, with the venous valve prosthesis implanted in a vein, the prosthetic valve in the closed configuration is configured to block blood from flowing past the prosthetic valve between a wall of the vein and the outer surface of the prosthetic valve, and
wherein, with the venous valve prosthesis implanted in the vein, the prosthetic valve is configured to move to the open configuration in response to antegrade blood flow through the vein to enable at least a portion of the antegrade blood flow to flow through the one or more slits and past the prosthetic valve.

2. The venous valve prosthesis of claim 1 , wherein, with the venous valve prosthesis implanted in the vein, the prosthetic valve is configured to move from the open configuration to the closed configuration in response to retrograde blood flow through the vein or absence of antegrade blood flow through the vein.

3. The venous valve prosthesis of claim 1 , wherein at least one slit of the one or more slits extends circumferentially around a portion of a circumference of the prosthetic valve.

4. The venous valve prosthesis of claim 1 , wherein the one or more slits comprise two slits, the two slits being diametrically opposed with respect to each other.

5. The venous valve prosthesis of claim 1 , wherein the prosthetic valve includes a tapered portion and a non-tapered portion.

6. The venous valve prosthesis of claim 5 , wherein the non-tapered portion includes a substantially cylindrical portion adjacent a larger end of the tapered portion.

7. The venous valve prosthesis of claim 5 , wherein at least one of the one or more slits extends through a portion of the tapered portion.

8. The venous valve prosthesis of claim 1 , wherein the prosthetic valve includes an upstream opening at an upstream end and a downstream opening at a downstream end, the prosthetic valve defining a prosthetic valve conduit between the upstream opening and the downstream opening, wherein the one or more slits are configured to enable fluid flow from the exterior of the frame to the prosthetic valve conduit.

9. The venous valve prosthesis of claim 8 , wherein the frame comprises a hub, the venous valve prosthesis further comprising a nose-piece configured to couple the prosthetic valve to the frame, wherein the nose-piece comprises a shaft configured to extend through the upstream opening of the prosthetic valve and engage the hub, the nose-piece defining a nose piece conduit in fluid communication with the prosthetic valve conduit.

10. The venous valve prosthesis of claim 8 , wherein the prosthetic valve is coupled to the frame by friction fit, a mechanical connection, or an adhesive connection.

11. The venous valve prosthesis of claim 1 , wherein the prosthetic valve comprises silicone or expanded polytetrafluoroethylene (ePTFE).

12. The venous valve prosthesis of claim 1 , wherein the frame is configured to expand radially outward from a radially compressed configuration to a radially expanded configuration.

13. The venous valve prosthesis of claim 1 , wherein the frame is a stent.

14. A venous valve prosthesis comprising:
a frame defining a longitudinal axis;
a prosthetic valve coupled to the frame and disposed about an exterior of the frame, the prosthetic valve defining a valve conduit extending from an upstream opening to a downstream opening, an outer surface, an inner surface, and one or more slits extending from the outer surface to the inner surface, the prosthetic valve having a closed configuration wherein the one or more slits are closed and an open configuration wherein the one or more slits are open; and
a nose-piece configured to couple the prosthetic valve to the frame, wherein the nose-piece defines a nose piece conduit in fluid communication with the valve conduit to enable fluid flow through the valve conduit when the one or more slits are in the closed configuration,
wherein, with the venous valve prosthesis implanted in a vein, the prosthetic valve in the closed configuration is configured to block blood from flowing past the prosthetic valve between a wall of the vein and the outer surface of the prosthetic valve, and
wherein, with the venous valve prosthesis implanted in the vein, the prosthetic valve is configured to move to the open configuration in response to antegrade blood flow through the vein to enable at least a portion of the antegrade blood flow to flow through the one or more slits, into the valve conduit, and past the prosthetic valve.

15. The venous valve prosthesis of claim 14 , wherein the at least one slit of the one or more slits extends circumferentially around a portion of a circumference of the prosthetic valve.

16. The venous valve prosthesis of claim 14 , wherein the one or more slits comprise two slits, the two slits being diametrically opposed with respect to each other.

17. The venous valve prosthesis of claim 14 , wherein the prosthetic valve includes a tapered portion and a non-tapered portion, wherein at least one of the one or more slits extends through a portion of the tapered portion.

18. The venous valve prosthesis of claim 14 , wherein, with the venous valve prosthesis implanted in the vein, the prosthetic valve is configured to move from the open configuration to the closed configuration in response to retrograde blood flow through the vein or absence of antegrade blood flow through the vein.

19. The venous valve prosthesis of claim 14 , wherein the prosthetic valve comprises silicone or expanded polytetrafluoroethylene (ePTFE).

20. The venous valve prosthesis of claim 14 , wherein the frame is a stent.

Assignees

• Medtronic Vascular Inc

Inventors

• Argentine Jeffery
• Malsbary Todd
• Perkins Keith
• Rowe Travis

Classifications

• A61F2/2433 Primary

  using balloon catheter · CPC title

• A61F2230/0067

  conical · CPC title

• A61F2/2436

  Deployment by retracting a sheath · CPC title

• A61F2230/001

  Figure-8-shaped, e.g. hourglass-shaped · CPC title

• A61F2/2475 Primary

  Venous valves · CPC title