Bioreactor with impeller assembly
US-10335751-B2 · Jul 2, 2019 · US
Methods for operating a bioreactor with impeller assembly and related bioreactors
US11654408B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11654408-B2 |
| Application number | US-201916421168-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 23, 2019 |
| Priority date | Mar 22, 2014 |
| Publication date | May 23, 2023 |
| Grant date | May 23, 2023 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector. Rotating the drive shaft so as to rotate the first tubular connector and the second tubular connector within the container.
First claim
Opening claim text (preview).
What is claimed is: 1. A bioreactor comprising: a flexible container; a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within the flexible container, the first tubular connector being more flexible than the second tubular connector, the first tubular connector having a length that comprises at least 20% of a combined length of the first tubular connector and the second tubular connector; at least one mixing element disposed on the second tubular connector; and a drive shaft disposed within the first tubular connector and the second tubular connector such that rotation of the drive shaft facilitates rotation of the first tubular connector and the second tubular connector within the flexible container. 2. The bioreactor as recited in claim 1 , wherein the length of the first tubular connector comprises at least 40% of the combined length of the first tubular connector and the second tubular connector. 3. The bioreactor as recited in claim 1 , wherein the at least one mixing element is removably disposed on the second tubular connector. 4. A bioreactor comprising: a flexible container; a tubular member that is at least partially disposed within the flexible container, the tubular member comprising a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector being more flexible than the second tubular connector, the first tubular connector having an interior surface that bounds a passage that extends through the first tubular connector; a first mixing element being disposed on the tubular member; and a drive shaft disposed within the first tubular connector and the second tubular connector of the tubular member such that rotation of the drive shaft facilitates rotation of the tubular member within the flexible container. 5. The bioreactor as recited in claim 4 , wherein the first mixing element is removably disposed on the tubular member. 6. The bioreactor as recited in claim 4 , wherein the first tubular connector has an exterior surface with a cylindrical configuration and the second tubular connector has an exterior surface with a polygonal transverse cross section. 7. The bioreactor as recited in claim 4 , further comprises a rotational assembly that includes: a casing mounted to the flexible container and having a passageway extending therethrough; and a hub rotatably mounted within the passageway of the casing, the hub having a passageway extending therethrough, the tubular member being coupled to the hub. 8. A bioreactor comprising: a flexible container; a tubular member that is at least partially disposed within the flexible container, the tubular member comprising a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector being more flexible than the second tubular connector, the first tubular connector having an exterior surface with a cylindrical configuration and the second tubular connector having an exterior surface with a polygonal transverse cross section; a first mixing element being disposed on the tubular member; and a drive shaft disposed within the first tubular connector and the second tubular connector of the tubular member such that rotation of the drive shaft facilitates rotation of the tubular member within the flexible container.
Assignees
Inventors
Classifications
rotatably mounted · CPC title
with agitation means; with heat exchange means · CPC title
- B01F27/80Primary
with stirrers rotating about a substantially vertical axis · CPC title
- B01F35/513Primary
Flexible receptacles, e.g. bags supported by rigid containers · CPC title
Flexible shafts · CPC title
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Frequently asked questions
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- What does patent US11654408B2 cover?
- A method for operating a bioreactor includes passing a drive shaft into a first tubular connector and a second tubular connector projecting from the first tubular connector, the first tubular connector and the second tubular connector being at least partially disposed within a container, the first tubular connector being more flexible than the second tubular connector, the second tubular connec…
- Who is the assignee on this patent?
- Life Technologies Corp
- What technology area does this patent fall under?
- Primary CPC classification B01F27/80. Mapped technology areas include Operations & Transport.
- When was this patent published?
- Publication date Tue May 23 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).