Balloon expandable frame for transcatheter implantation of a cardiac valve prosthesis

Patent metadata

Field	Value
Publication number	US-11648109-B2
Application number	US-202016778688-A
Country	US
Kind code	B2
Filing date	Jan 31, 2020
Priority date	Feb 4, 2019
Publication date	May 16, 2023
Grant date	May 16, 2023

Abstract

A transcatheter valve prosthesis includes a balloon expandable stent and a prosthetic valve. An inflow portion of the stent includes a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts. Endmost inflow side openings and endmost inflow crowns are formed at the inflow end of the stent and the inflow end of the stent has a total of twelve endmost inflow crowns. An outflow portion of the stent includes a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts. Endmost outflow crowns are formed at the outflow end of the stent and the outflow end of the stent has a total of six endmost outflow crowns. The prosthetic valve is disposed within and secured to the stent.

First claim

What is claimed is:

1. A transcatheter valve prosthesis comprising:
a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, wherein the stent is balloon expandable, the stent including
an inflow portion formed proximate to an inflow end of the stent, the inflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, a plurality of side openings being defined by the plurality of crowns and the plurality of struts, wherein endmost inflow side openings and endmost inflow crowns are formed at the inflow end of the stent and the inflow end of the stent has a total of twelve endmost inflow crowns,
an outflow portion formed proximate to an outflow end of the stent, the outflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, wherein endmost outflow crowns are formed at the outflow end of the stent and the outflow end of the stent has a total of six endmost outflow crowns, and wherein a diameter of the inflow end of the stent is the same as a diameter of the outflow end of the stent, and
a transition portion extending between the inflow portion and the outflow portion, wherein the transition portion includes a total of six axial frame members and a total of six endmost outflow side openings are formed at the outflow end of the stent, each endmost outflow side opening being defined by two struts of the outflow portion, four struts of the inflow portion, and two axial frame members of the transition portion, and

a prosthetic valve disposed within and secured to at least the transition portion of the stent, the prosthetic valve being configured to block blood flow in one direction to regulate blood flow through a central lumen of the stent.

2. The transcatheter valve prosthesis of claim 1 , wherein the prosthetic valve includes three leaflets and three commissures, each commissure being formed by attached adjacent lateral ends of an adjoining pair of the three leaflets.

3. The transcatheter valve prosthesis of claim 2 , wherein each axial frame member extends between a crown of the outflow portion and a crown of the inflow portion and each axial frame member disposed approximately halfway between a pair of adjacent endmost outflow crowns, and wherein three of the six axial frame members are aligned with and attached to a respective commissure of the three leaflets of the prosthetic valve.

4. The transcatheter valve prosthesis of claim 2 , wherein the three leaflets are attached to the stent along a margin of attachment that follows struts and nodes of the inflow portion of the stent, a node being defined as a region where two crowns of the plurality of crowns within the inflow portion connect, wherein the margin of attachment has a smooth concave shape and wherein the two crowns that connect at each node overlap.

5. The transcatheter valve prosthesis of claim 2 , wherein struts adjacent to the six endmost outflow crowns are endmost struts and a plurality of holes are formed within the endmost struts, the plurality of holes configured to attach a respective commissure of the three leaflets of the prosthetic valve to the stent.

6. The transcatheter valve prosthesis of claim 5 , wherein the transition region is formed by a connection between abutting crowns of the outflow portion and crowns of the inflow portion, the connection having an increased width relative to the plurality of struts of the outflow portion.

7. The transcatheter valve prosthesis of claim 5 , wherein a generally triangular material flap is attached to the plurality of holes and the respective commissure of the three leaflets of the prosthetic valve is attached to the generally triangular material flap.

8. The transcatheter valve prosthesis of claim 1 , wherein each axial frame member is attached to a respective endmost outflow crown.

9. The transcatheter valve prosthesis of claim 1 , wherein at least one strut of the inflow portion is tapered and the thickness varies along a length thereof such that a middle portion is relatively thinner than opposing end portions of the strut.

10. A transcatheter valve prosthesis comprising:
a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, wherein the stent is balloon expandable, the stent including
a plurality of axial frame members, each axial frame member having an inflow end and an outflow end,
an inflow portion including at least three rows of struts and crowns formed between adjacent pairs of said struts, wherein the at least three rows of the inflow portion are formed between the inflow ends of the axial frame members and an inflow end of the stent, and
an outflow portion including a single row of struts and crowns formed between adjacent pair of said struts, the outflow portion being coupled to the outflow ends of the axial frame members, wherein exactly two struts of the plurality of struts of the outflow portion are disposed between adjacent axial frame members, and
wherein each of the axial frame members extends between the inflow portion and the outflow portion of the stent and at least one of the axial frame members is a commissure post.

11. The transcatheter valve prosthesis of claim 10 ,
wherein the plurality of axial frame members includes exactly six axial frame members,
wherein three of the six axial frame members are commissure posts and three of the six axial frame members are axial struts, and
wherein each of the axial struts is disposed between adjacent commissure posts.

12. The transcatheter valve prosthesis of claim 11 , further compering a prosthetic valve including three leaflets, wherein each commissure of the leaflets is coupled to a corresponding commissure post of the stent.

13. The transcatheter valve prosthesis of claim 10 , wherein one of the at least three rows of struts and crowns of the inflow portion includes crowns coupled to the inflow end of the axial frame member, wherein the one row includes exactly four struts between adjacent axial frame members.

Assignees

• Medtronic Inc

Inventors

• Peterson Justin
• Goshgarian Justin
• Kari Stuart
• Tien Tracey
• Krivoruchko Michael
• Neuberger Yas

Classifications

• A61F2/2433

  using balloon catheter · CPC title

• A61F2230/0006

  circular · CPC title

• A61F2/2418 Primary

  Scaffolds therefor, e.g. support stents · CPC title

• A61F2250/0036

  differing in thickness · CPC title

• A61F2/9522

  Means for mounting a stent or stent-graft onto or into a placement instrument · CPC title