Methods for deploying a prosthetic mitral valve

Patent metadata

Field	Value
Publication number	US-11583394-B2
Application number	US-201916655656-A
Country	US
Kind code	B2
Filing date	Oct 17, 2019
Priority date	May 20, 2011
Publication date	Feb 21, 2023
Grant date	Feb 21, 2023

Abstract

According to an aspect of some embodiments of the invention, there is provided a method of deploying an expandable prosthetic mitral valve in a subject, the method comprising: deploying a first component of the prosthetic mitral valve in a left atrium; deploying a second component of the prosthetic mitral valve in a left ventricle; and approximating the first and the second components so that leaflets of a native mitral valve are trapped between the first and the second components.

First claim

What is claimed is:

1. A method comprising:
deploying an expandable prosthetic mitral valve device in a heart of a subject, by:
deploying a first component of the prosthetic mitral valve device in a left atrium of the subject, the first component including an annulus part that is deployed at least partially in a vicinity of a native mitral annulus of the subject;
deploying a second component of the prosthetic mitral valve in a left ventricle of the subject, the second component including a ventricular part,
deployment of the first component and the second component being performed such that there is a gap between the ventricular part and the annulus part, the gap being configured to accommodate one or more leaflets of the native mitral valve;

approximating the first and second components with respect to each other, such that, when the first and said second components are in an approximated configuration with respect to each other, the one or more leaflets of the native mitral valve are trapped within the gap between the ventricular part and the annulus part; and
securing the annulus part and the ventricular part in the approximated configuration.

2. The method according to claim 1 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other by pulling a wire connecting said first and second components.

3. The method according to claim 1 , further comprising piercing the leaflets of the native mitral valve by at least one of said first or said second components.

4. The method according to claim 1 , further comprising piercing tissue surrounding the leaflets of the native mitral valve by at least one of said first or said second components.

5. The method according to claim 1 , wherein approximating the first and second components with respect to each other comprises pulling the ventricular part toward the annulus part such that the ventricular part at least partially encircles both a portion of the annulus part and the one or more leaflets of the native mitral valve.

6. The method according to claim 1 , wherein deploying the expandable prosthetic mitral valve device in the subject's heart further comprises deploying the expandable prosthetic mitral valve device in the subject's heart using at least one of a transapical approach and a vascular approach.

7. The method according to claim 1 , wherein deploying the expandable prosthetic mitral valve device in the subject's heart further comprises deploying the expandable prosthetic mitral valve device in the subject's heart using a transseptal approach.

8. The method according to claim 1 , wherein the annulus part includes a valve mechanism suitable for functioning as a prosthetic mitral valve.

9. The method according to claim 1 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other using at least one elongated tether having a first end functionally associated with the annulus part and a second end configured for securing in proximity of an apex of the subject's heart, so that a force applied to said second end of said tether is at least partially transferred by said annulus part to an atrial surface in a vicinity of the subject's native mitral valve annulus.

10. The method according to claim 1 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other using at least one elongated tether having a first end functionally associated with said ventricular part and a second end configured for securing in proximity of an apex of said heart, wherein a portion of said tether passes through said annulus part so that force applied to the second end of the tether pulls the ventricular part towards said annulus part, and is at least partially transferred by the annulus part to an atrial surface in a vicinity of the subject's native mitral valve annulus.

11. The method according to claim 1 , wherein at least one of said annulus part and said ventricular part includes mating features, and wherein approximating the first and second components with respect to each other comprises bending the mating features.

12. The method according to claim 1 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other using a deployable tether.

13. The method according to claim 1 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other using a plurality of filaments each of which extends from the deployment device at one filament end to another filament end that is secured to the ventricular part, each of the filaments contacting a region of slidable association with the annulus part between the filament ends.

14. The method according to claim 13 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other using a plurality of filaments that are releasably secured to said ventricular part.

15. The method according to claim 13 , wherein approximating the first and second components with respect to each other comprises approximating the first and second components with respect to each other using a plurality of filaments that are fixedly secured to said ventricular part.

Assignees

• Tel Hashomer Medical Res Infrastructure & Services Ltd
• Tel Hashomer Med Rsch Infra And Services Ltd

Inventors

• Orlov Boris
• Raanani Ehud

Classifications

• A61F2250/006

  modular · CPC title

• A61F2/2427

  Devices for manipulating or deploying heart valves during implantation · CPC title

• A61F2/2436 Primary

  Deployment by retracting a sheath · CPC title

• A61F2230/0054

  V-shaped · CPC title

• A61F2/95

  Instruments specially adapted for placement or removal of stents or stent-grafts · CPC title