Endovascular apparatus for perfusing organs in a body

Patent metadata

Field	Value
Publication number	US-11559055-B2
Application number	US-201916397704-A
Country	US
Kind code	B2
Filing date	Apr 29, 2019
Priority date	Feb 4, 2014
Publication date	Jan 24, 2023
Grant date	Jan 24, 2023

Abstract

In one representative embodiment, a method of perfusing organs in a patient's body is provided. The method comprises isolating the visceral arteries and the visceral veins from blood circulating through the patient's heart and perfusing the visceral arteries, the visceral veins, and the abdominal organs with a perfusion fluid that is fluidly separated from the blood circulating through the patient's heart. While the visceral arteries and the visceral veins are isolated, and the visceral arteries, the visceral veins, and the abdominal organs are being perfused, the patient's blood is allowed to continue to circulate through the heart.

First claim

We claim:

1. A perfusion stent implantable within a body lumen, the stent comprising:
a radially compressible and expandable, elongated body comprising first and second end portions and an intermediate portion extending from the first end portion to the second end portion;
the first and second end portions having an outer diameter greater than an outer diameter of the intermediate portion when the body is in a radially expanded state, thereby defining an annular perfusion space between the first and second end portions and around the intermediate portion, wherein the first and second end portions comprise a cylindrical first section and a tapered second section positioned proximal to the first section when in the radially expanded state;
a central lumen extending through the first end portion, the intermediate portion, and the second end portion; and
a perfusion lumen extending at least partially through the first end portion and having a distal opening in communication with the perfusion space;
wherein the elongated body comprises a self-expandable frame and when the elongated body is in the radially expanded state within the body lumen and the first and second end portions are engaged with an inner wall of the body lumen, the central lumen is fluidly separated from the perfusion space, and
wherein a proximal end of the self-expandable frame is connected to a recovery wire comprising a retractable sheath.

2. The perfusion stent of claim 1 , further comprising a perfusion conduit extending at least partially through the first end portion, the perfusion conduit defining the perfusion lumen.

3. The perfusion stent of claim 1 , wherein the body comprises an inlet and an outlet of the central lumen and a surface that is non-porous to blood surrounding the central lumen and extending longitudinally from the inlet to the outlet.

4. The perfusion stent of claim 1 , wherein the body comprises a liner attached to the self-expandable frame, the liner defining the surface that is non-porous to blood.

5. The perfusion stent of claim 4 , wherein the self-expandable frame comprises a micropatterned Nitinol film and the liner comprises polymeric film.

6. The perfusion stent of claim 4 , wherein the self-expandable frame of the first and second end portions comprises angled struts.

7. The perfusion stent of claim 4 , wherein the liner is secured to the self-expandable frame by an adhesive or suturing.

8. The perfusion stent of claim 4 , wherein the liner is located outside of the self-expandable frame, inside of the self-expandable frame, or on both the outside and inside of the self-expandable frame.

9. The perfusion stent of claim 1 , wherein the first and second end portions comprise a positioning marker.

10. The perfusion stent of claim 9 , wherein the positioning marker is a radiopaque marker.

11. The perfusion stent of claim 10 , wherein the positioning marker comprises a passive or active electromagnetic wave emitter.

Assignees

• Univ Of Pittsburgh—Of The Commonwealth System Of Higher Education

Inventors

• Tillman Bryan W
• Tevar Amit D
• Chun Youngjae

Classifications

• A01N1/0226

  Human Necessities · mapped topic

• A01N1/0247 Primary

  Human Necessities · mapped topic

• A61B2017/00969

  used for transplantation · CPC title

• A61M2025/1095

  with perfusion means for enabling blood circulation while the balloon is in an inflated state or in a deflated state, e.g. permanent by-pass within catheter shaft · CPC title

• A01N1/0242

  Human Necessities · mapped topic