Cardiac compression device having passive and active chambers

Patent metadata

Field	Value
Publication number	US-11511102-B2
Application number	US-201615365223-A
Country	US
Kind code	B2
Filing date	Nov 30, 2016
Priority date	Jun 17, 2004
Publication date	Nov 29, 2022
Grant date	Nov 29, 2022

Abstract

The present invention provides methods, systems, kits, and cardiac compression devices that have both passive chambers and active chambers to improve heart function.

First claim

What is claimed is:

1. A direct cardiac compression device adapted to surround a heart comprising
an inner passive chambers to provide adjustable passive support comprising:
an inner membrane adapted to at least partially surround the heart,
a connecting membrane in communication with the inner membrane to form inner passive chambers, and
a passive fluid deposited in the inner passive chambers, wherein the inner passive chambers conform to the shape of the heart and are adjustable to reduce the volume of the heart, without inverting the curvature of the heart;

an outer active chambers adapted to at least partially surround the inner passive chambers comprising:
an outer member in communication with the connecting membrane, to form outer active chambers, and
an active fluid disposed in the outer active chambers, wherein the active fluid increases in pressure and presses on the inner passive chambers which in turn compress the heart.

2. The device of claim 1 , further comprising one or more passive dividers located between the inner membrane and the connecting membrane to form passive chambers.

3. The device of claim 1 , further comprising one or more active dividers located between the outer membrane and the connecting membrane to form baffled chambers.

4. The device of claim 1 , wherein the outer membrane and the connecting membrane are the same membrane.

5. The device of claim 1 , wherein the inner membrane and the connecting membrane are sealed together; wherein the connecting membrane and the outer membrane are sealed together.

6. A direct cardiac compression device adapted to surround the heart comprising
an inner passive chambers to provide adjustable passive support comprising:
an inner membrane adapted to surround the heart,
a connecting membrane in communication with the inner membrane to form an inner passive chambers, and
a passive fluid deposited in the inner passive chambers, wherein the inner passive chamber conforms to the shape of the heart and are adjustable to reduce the volume of the heart, without inverting the curvature of the heart;

an outer active chambers comprising:
an outer member in communication with the connecting membrane to form an outer active chambers, and

an active fluid disposed in the outer active chambers, wherein the active fluid is adapted to press on the connecting membrane to compress the heart when the active fluid is increase in volume.

7. The device of claim 6 , further comprising a pneumatic driver operably linked to pressurize the outer active chambers to compress the heart and to depressurize the outer active chambers.

8. The device of claim 6 , wherein the passive fluid maintains a constant volume.

9. The device of claim 6 , wherein the passive fluid is a liquid, a gas, a gel, or a polymer.

10. The device of claim 6 , wherein the passive fluid is saline.

11. The device of claim 6 , wherein the active fluid is a gas.

12. The device of claim 6 , further comprising one or more inner passive dividers positioned between the inner passive membrane and the connecting membrane to form 2 or more passive chambers.

13. The device of claim 6 , further comprising one or more active dividers positioned between the outer member and the connecting membrane to form 2 or more active chambers.

14. The device of claim 6 , wherein the inner passive membrane is contoured to surround the heart operable to actively promote a contraction strain pattern characterized by non-inversion or lack of gross perturbation of the curvature on a diseased or damaged myocardium that promotes beneficial growth and remodeling of the myocardium.

15. The device of claim 6 , wherein and the device exerts a non-curvature-inverting contraction stain pattern when used on a heart, when the fluid is pressurized.

16. The device of claim 6 , further comprising a passive port in communication with the passive fluid to adjust a passive fluid volume.

17. The device of claim 6 , further comprising a shell surrounding the outer member.

18. The device of claim 6 , wherein the device applies varying pressure, uniform pressure or both to the surface of the heart to alter an end systolic configuration of the heart, an end diastolic configuration of the heart, or both.

19. The device of claim 6 , wherein the inner film, the outer film, or both are a biocompatible film that form one or more enclosures or bladders that are adapted to be filled with a fluid.

20. The device of claim 6 , further comprising one or more components designed to provide adjustable passive support, active assist, or a combination of active assist and passive support to a damaged or diseased heart.

21. The device of claim 6 , wherein the inner membrane is adapted to form a pneumatic lock with the heart surface.

22. The device of claim 6 , further comprising one or more structural elements disposed about the direct cardiac compression device.

23. A direct cardiac compression device adapted to surround a heart and comprising:
an inner passive chambers comprising:
an inner membrane adapted to surround the heart,
a connecting membrane in communication with the inner membrane,
one or more passive dividers located between the inner membrane and the connecting membrane to form inner passive chambers, and
a passive fluid deposited in the inner passive chambers, wherein the inner passive chambers conform to the shape of the heart and are adjustable to reduce the volume of the heart, without inverting the curvature of the heart;

an outer active chambers comprising:
an outer member in communication with the connecting membrane, one or more active dividers located between the outer member and the connecting membrane to form outer active chambers, and
an active fluid disposed in the outer active chambers;
an input connection in fluid communication with the outer active chambers to ingress the active fluid into the outer active chambers, and
an output connection in fluid communication with the outer active chambers to egress the fluid from the outer active chambers, wherein the active fluid presses on the inner passive chambers to compress the heart.

Assignees

• Texas A & M Univ Sys
• Corinnova Incorporated

Inventors

• Criscione John C
• Harrison Lewis D
• Moreno Michael R
• Bolch Christina M
• Robbins Dennis I
• Biswas Saurabh
• Leschinsky Boris

Classifications

• A61M60/468

  the force acting on the actuation means being hydraulic or pneumatic · CPC title

• A61M60/839

  of devices for mechanical circulatory actuation · CPC title

• A61M60/289

  Devices for mechanical circulatory actuation assisting the residual heart function by means mechanically acting upon the patient's native heart or blood vessel structure, e.g. direct cardiac compression [DCC] devices · CPC title

• A61M60/191

  mechanically acting upon the outside of the patient's native heart, e.g. compressive structures placed around the heart · CPC title

• A61M60/148

  in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices · CPC title