Biphasic and dynamic adjustable support devices and methods with assist and recoil capabilities for treatment of cardiac pathologies

Patent metadata

Field	Value
Publication number	US-9259520-B2
Application number	US-201414577218-A
Country	US
Kind code	B2
Filing date	Dec 19, 2014
Priority date	Jul 22, 2009
Publication date	Feb 16, 2016
Grant date	Feb 16, 2016

Abstract

The present invention provides a biphasic and dynamic direct cardiac contact device adapted to be implanted in a patient suffering from congestive heart failure and related cardiac pathologies, said cardiac device having means for providing ventricular assist, ventricular support and diastolic recoil, or for providing ventricular support and diastolic recoil only.

First claim

What is claimed:

1. A method of using a direct cardiac contact ventricular assist, ventricular support and diastolic recoil device or a direct cardiac contact ventricular support and diastolic recoil device only, comprising the steps of:
providing a biphasic direct cardiac contact device that can separately modulate an end systolic configuration and an end diastolic configuration of a heart comprising:
an adjustable passive support component in contact with an epicardial surface of the heart to continually apply support to the heart, wherein the adjustable passive support component constrains ventricle filling when the cardiac volume exceeds a target end diastolic volume and
an elastic memory component in contact with the adjustable passive support component wherein the elastic memory component creates a negative pressure that promotes ventricle filling when a cardiac volume is lower than a target end diastolic volume;

determining the target end diastolic volume for the heart;
determining a phase transitioning point from the target end diastolic volume; and
operating the biphasic direct cardiac contact device in a biphasic mode about the phase transition point, wherein the phase transition point is an adjustable phase transition point adjustable about the target end diastolic volume for the heart.

2. The method of claim 1 , further comprising the steps of:
enhancing filling in a filling enhancement phase when cardiac volumes are below the target end diastolic volume; and
impeding filling (i.e., “filling impediment” phase) when cardiac volumes above the target end diastolic volume.

3. The method of claim 2 , wherein the filling enhancement of the biphasic component enhances diastolic recoil when the elastic memory component is utilized when cardiac pressures are lower than the target end diastolic volume by creating a negative pressure that promotes ventricle filling and when cardiac pressure exceed the target end diastolic volume, filling and cardiac volume is constrained.

4. The method of claim 1 , comprising the step of using a dynamic adjustable support during the filling impediment of the biphasic component.

5. The method of claim 1 , comprising the step of continually applying support to the epicardial surface of the heart, thereby promoting reverse remodeling.

6. The method of claim 1 , wherein as the diseased heart begins to respond to the support by becoming smaller, adjusting the target end diastolic volume to provide the same amount of support as an initial treatment intervention.

7. A direct cardiac contact diastolic recoil device to improve diastolic recoil of a heart and reduce postoperative pericardial adhesion comprising:
a first biocompatible film for adhesion to the epicardial surface of the heart;
an elastic memory component in contact with the first biocompatible film wherein the elastic memory component creates a negative pressure on the heart to promote ventricle filling when a cardiac volume is lower than a target end diastolic volume;
a second biocompatible film for adhesion to the chest cavity; and
one or more fluid filled bladders that separate the first biocompatible film and the second biocompatible film to prevent adhesion between the epicardial surface of the heart and the chest wall.

Assignees

• Texas A & M Univ Sys
• Corlnnova Inc
• Corinnova Inc

Inventors

• Altman William C
• Biswas Saurabh
• Criscione John C
• Harrison Lewis D
• Moreno Michael R
• Robbins Dennis I

Classifications

• A61F2250/0003

  having an inflatable pocket filled with fluid, e.g. liquid or gas · CPC title

• A61F2/2481 Primary

  Devices outside the heart wall, e.g. bags, strips or bands · CPC title

• A61F2220/0008

  Fixation appliances for connecting prostheses to the body · CPC title

• A61M1/1068 Primary

  Human Necessities · mapped topic

• A61M1/122

  Human Necessities · mapped topic