Submicronic emulsion

Patent metadata

Field	Value
Publication number	US-11414604-B2
Application number	US-201816759940-A
Country	US
Kind code	B2
Filing date	Dec 21, 2018
Priority date	Dec 21, 2017
Publication date	Aug 16, 2022
Grant date	Aug 16, 2022

Abstract

The invention relates to a process for preparing a dispersion of a lipophilic compound in a continuous hydrophilic phase, the morphology of which is submicronic. During the preparation of this dispersion, there is applied, by means of a device which produces a shearing gradient less than 5000 s−1, a shear stress from 100 to 5000 Pa during the addition of the lipophilic compound in the continuous phase which comprises a rheology-modifying compound selected from anionic copolymers, preferably an anionic polymer, in particular an ASE polymer or a HASE polymer. The dispersed particles of the lipophilic compound are nanometric particles whose size is less than 1 μm. The dispersion, particularly in the form of an emulsion, can be used in numerous fields.

First claim

The invention claimed is:

1. A method of preparing a dispersion comprising a continuous hydrophilic phase and a lipophilic phase dispersed in the continuous hydrophilic phase in the form of nanometric particles, the method comprising:
preparing a mixture comprising a hydrophilic compound and a rheology-modifying compound of the hydrophilic compound, and
adding a lipophilic compound in the continuous hydrophilic phase by applying, using a device producing a shear gradient of less than 5,000 s −1 , a stress chosen among a shear stress ranging from 100 to 5,000 Pa and an extensional stress ranging from 100 to 5,000 Pa,
wherein the continuous hydrophilic phase comprises the hydrophilic compound and the rheology-modifying compound, and
the rheology-modifying compound is an anionic copolymer.

2. The method according to claim 1 , wherein:
the continuous hydrophilic phase has a viscosity ranging from 20 to 50,000 mPa·s;
the dispersion has a viscosity ranging from 20 to 50,000 mPa·s;
the dispersion is an emulsion; or
the dispersion comprises from 0.1 to 75% by weight of dispersed lipophilic phase relative to the total amount by weight of the continuous hydrophilic phase and of the dispersed lipophilic phase.

3. The method according to claim 1 , wherein the hydrophilic compound is chosen among water alone or in combination with at least one compound chosen among glycerol, polyglycerols, glycols, moistening compounds, sugar derivatives, and coalescing agents.

4. The method according to claim 1 ,
wherein the rheology-modifying compound has a pH greater than 5; or
the rheology-modifying compound is at least one selected from the group consisting
of an ASE copolymer and a HASE copolymer.

5. The method according to claim 1 , wherein the mixture also comprises a base; and
the mixture has a pH greater than 5.

6. The method according to claim 1 , wherein the mixture comprises from 0.5 to 15% by weight of a rheology modifier.

7. The method according to claim 1 , wherein:
the preparation temperature is lower than a boiling point of the continuous hydrophilic phase and lower than a boiling point of the lipophilic phase;
the preparation temperature is higher than a melting point of the continuous hydrophilic phase and higher than a melting point of the lipophilic phase; or
the preparation temperature is lower than the boiling point of the continuous hydrophilic phase and lower than the boiling point of the lipophilic phase while being higher than the melting point of the continuous hydrophilic phase and higher than the melting point of the lipophilic phase.

8. The method according to claim 1 , wherein the dispersion is an emulsion of a dispersed lipophilic phase in the continuous hydrophilic phase.

9. The method according to claim 1 , wherein the shear stress or the extensional stress ranges from 300 to 5,000 Pa;
the shear stress or the extensional stress is also applied when preparing the mixture; or
the stress is applied using a device that produces a shear gradient of less than 2,000 s −1 or using a device that produces a shear gradient ranging from 100 to 5,000 s −1 .

10. The method according to claim 1 ,
wherein a mean size (measured by light scattering) of dispersed particles of lipophilic phase is submicronic.

11. The method according to claim 1 , further comprising:
neutralisation of the dispersion; or
partial coacervation of the rheology-modifying compound.

12. A dispersion prepared by the method according to claim 1 .

13. A product comprising the dispersion according to claim 12 .

14. An article, comprising the dispersion according to claim 12 wherein the article is selected from the group consisting of cosmetics, paints, dyes, printing, inks, construction, fuels, lubricants, anti-foaming agents, metallurgy, fertilisers, pharmaceuticals, agro-chemicals, crop protection products, detergents, food, leather, and coating.

15. The method according to claim 5 , wherein the pH ranges from greater than 5 to 12.

16. The method according to claim 1 , wherein the mixture further comprises from 0.05 to 10% by weight of the mixture of a surface-active compound.

17. The method according to claim 1 , wherein the mixture does not comprise any surface-active compound.

Assignees

• Coatex Sas

Inventors

• Champagne Clementine
• Suau Jean-Marc

Classifications

• C08F290/046 Primary

  Polymers of unsaturated carboxylic acids or derivatives thereof · CPC title

• B01F23/4105 Primary

  Methods of emulsifying · CPC title

• C09K23/00 Primary

  Use of substances as emulsifying, wetting, dispersing, or foam-producing agents · CPC title

• B01F2215/0495

  Numerical values of viscosity of substances · CPC title

• C08F220/1802

  C2-(meth)acrylate, e.g. ethyl (meth)acrylate · CPC title