Particle beam treatment system, particle beam treatment method, and computer program product

Patent metadata

Field	Value
Publication number	US-11413476-B2
Application number	US-201916413933-A
Country	US
Kind code	B2
Filing date	May 16, 2019
Priority date	Sep 19, 2014
Publication date	Aug 16, 2022
Grant date	Aug 16, 2022

Abstract

According to an embodiment, a particle beam treatment system includes a storage, an estimator, a target value generator, and a particle beam treatment device. The storage stores therein a respiratory movement model obtained by synchronizing amount of displacement of an affected area of a subject with a signal related to respiration of the subject and performing modeling. The estimator estimates, based on the measured signal related to respiration and the respiratory movement model, amount of displacement of the affected area corresponding to the measured signal. The target value generator generates a target value, which is used for performing movement control on a platform on which the subject is lying down, corresponding to the estimated amount of displacement of the affected area. The particle beam treatment device irradiates, with particle beams, the affected area of the subject on the platform subjected to movement control according to the target value.

First claim

What is claimed is:

1. A treatment apparatus comprising:
a memory configured to store therein a respiratory movement model representing positions of an affected area of a test subject, the positions synchronizing with respiration of the test subject; and
one or more hardware processors to which a monitor device and a respiration sensor configured for detecting respiration of the test subject are connected, the one or more hardware processors being configured to:
calculate a respiration signal representing a state of respiration of the test subject by using a sensor output from the respiration sensor;
estimate a current respiration phase of the respiration signal by comparing the respiration signal with the respiratory movement model;
estimate, from the respiratory movement model, a position of the affected area of the test subject corresponding to the estimated current respiration phase;
control the monitor device to display a waveform of the respiratory movement model and a waveform of the respiration signal whose phase synchronizes with a phase of the waveform of the respiratory movement model; and
control the monitor device to display a phase marker indicative of the estimated current respiration phase and the estimated position of the affected area of the test subject, the phase marker being displayed both on the waveform of the respiratory movement model and on the waveform of the respiration signal.

2. The apparatus according to claim 1 , wherein the one or more hardware processors are configured to:
calculate a respiratory movement signal indicative of one of the positions of the affected area attributed to respiration of the test subject, from a plurality of captured images in which a movement of the affected area is captured; and
generate the respiratory movement model by synchronizing the respiratory movement signal with the respiration signal and performing modeling.

3. The apparatus according to claim 1 , wherein an autoregressive model is used as the respiratory movement model.

4. The apparatus according to claim 1 , wherein the one or more hardware processors are configured to control the monitor device to move the phase marker in synchronization with a current value of the respiration signal.

5. A treatment method comprising:
storing, in a memory, a respiratory movement model representing positions of an affected area of a test subject, the positions synchronizing with respiration of the test subject;
calculating a respiration signal representing a state of respiration of the test subject by using a sensor output from a respiration sensor configured for detecting respiration of the test subject;
estimating a current respiration phase of the respiration signal by comparing the respiration signal with the respiratory movement model;
estimating, from the respiratory movement model, a position of the affected area of the test subject corresponding to the estimated current respiration phase;
controlling a monitor device to display a waveform of the respiratory movement model and a waveform of the respiration signal whose phase synchronizes with a phase of the waveform of the respiratory movement model; and
controlling the monitor device to display a phase marker indicative of the estimated current respiration phase and the estimated position of the affected area of the test subject, the phase marker being displayed both on the waveform of the respiratory movement model and on the waveform of the respiration signal.

6. The method according to claim 5 , further comprising controlling the monitor device to move the phase marker in synchronization with a current value of the respiration signal.

7. A computer program product comprising a non-transitory computer-readable medium including instructions, wherein the instructions, when executed by a computer, cause the computer to perform:
storing, in a memory, a respiratory movement model representing positions of an affected area of a test subject, the positions synchronizing with respiration of the test subject;
calculating a respiration signal representing a state of respiration of the test subject by using a sensor output from a respiration sensor configured for detecting respiration of the test subject;
estimating a current respiration phase of the respiration signal by comparing the respiration signal with the respiratory movement model;
estimating, from the respiratory movement model, a position of the affected area of the test subject corresponding to the estimated current respiration phase;
controlling a monitor device to display a waveform of the respiratory movement model and a waveform of the respiration signal whose phase synchronizes with a phase of the waveform of the respiratory movement model; and
controlling the monitor device to display a phase marker indicative of the estimated current respiration phase and the estimated position of the affected area of the test subject, the phase marker being displayed both on the waveform of the respiratory movement model and on the waveform of the respiration signal.

8. The computer program product according to claim 7 , wherein the instructions further cause the computer to perform controlling the monitor device to move the phase marker in synchronization with a current value of the respiration signal.

9. A treatment system comprising:
a memory configured to store therein a respiratory movement model representing positions of an affected area of a test subject, the positions synchronizing with respiration of the test subject;
one or more hardware processors to which a monitor device and a respiration sensor configured for detecting respiration of the test subject are connected, the one or more hardware processors being configured to:
calculate a respiration signal representing a state of respiration of the test subject by using a sensor output from the respiration sensor;
estimate a current respiration phase of the respiration signal by comparing the respiration signal with the respiratory movement model;
estimate, from the respiratory movement model, a position of the affected area of the test subject corresponding to the estimated current respiration phase;
control the monitor device to display a waveform of the respiratory movement model and a waveform of the respiration signal whose phase synchronizes with a phase of the waveform of the respiratory movement model;
control the monitor device to display a phase marker indicative of the estimated current respiration phase and the estimated position of the affected area of the test subject, the phase marker being displayed both on the waveform of the respiratory movement model and on the waveform of the respiration signal; and
generate a target value, which is used for performing movement control on a platform on which the test subject is lying down, on the basis of the estimated current position of the affected area; and

a particle beam treatment device configured to irradiate, with particle beams, the affected area of the test subject who is lying down on the platform which is subjected to movement control according to the target value.

10. The system according to claim 9 , wherein the one or more hardware processors are configured to control the monitor device to move the phase marker in synchronization with a current value of the respiration signal.

Assignees

• Toshiba Kk

Inventors

• Ooga Junichiro
• Ito Hideki
• Sugiyama Nobukatsu
• Oonishi Atsuro

Classifications

• A61N5/1078

  Fixed beam systems · CPC title

• A61N5/1049

  for verifying the position of the patient with respect to the radiation beam · CPC title

• A61N5/1037

  taking into account the movement of the target, e.g. 4D-image based planning · CPC title

• A61N5/107 Primary

  in real time, i.e. during treatment · CPC title

• A61N2005/1087

  Ions; Protons · CPC title